Search results for "gut"

Beyond Physical Exercise: The Role of Nutrition, Gut Microbiota and Nutraceutical Supplementation in Reducing Age-related Sarcopenia

2021

Sarcopenia is a commonly prevalent geriatric condition mainly characterized by progressive loss of the skeletal muscle mass that results in noticeably reduced muscle strength and quality. Most of the geriatric population above 60 years of age are overweight, leading to the accumulation of fat in the muscles resulting in abated muscle function. The increased loss of muscle mass is associated with high rates of disability, poor motility, frailty and mortality. The excessive degeneration of muscles is now also being observed in middle-aged people. Therefore, geriatrics has recently started shifting towards the identification of early stages of the disability in order to expand the life span o…

High scale mixing relations as a natural explanation for large neutrino mixing

2015

The origin of small mixing among the quarks and a large mixing among the neutrinos has been an open question in particle physics. In order to answer this question, we postulate general relations among the quarks and the leptonic mixing angles at a high scale, which could be the scale of Grand Unified Theories. The central idea of these relations is that the quark and the leptonic mixing angles can be unified at some high scale either due to some quark-lepton symmetry or some other underlying mechanism and as a consequence, the mixing angles of the leptonic sector are proportional to that of the quark sector. We investigate the phenomenology of the possible relations where the leptonic mixin…

Renato Guttuso Celebrazioni per il centenario dalla nascita 1911-2011

2011

Il volume raccoglie alcuni saggi dedicati al pittore Renato Guttuso (1911-2011) nel centenario dalla nascita. In particolare Rosario Scaduto nei suoi due saggi fa conoscere, per tutelare e conservare, la casa natale e la casa d'infanzia con il primo studio di pittura di Guttuso a Bagheria, in Provincia di Palermo. Oltre a detti saggi, nel volume sono anche inserite alcune testimonianze di Dora Favatella Lo Cascio (direttore del Museo Guttuso di Bagheria), Fabio Carapezza Guttuso (presidente degli Archivi Guttuso di Roma e componente del direttivo del Museo Guttuso di Bagheria), di Goacchino Guttuso Fasulo (padre di Renato Guttuso) e dello stesso Renato Guttuso. In tutti gli interventi emerg…

Impact of probiotic Saccharomyces boulardii on the gut microbiome composition in HIV-treated patients: A double-blind, randomised, placebo-controlled…

2017

Dysbalance in gut microbiota has been linked to increased microbial translocation, leading to chronic inflammation in HIV-patients, even under effective HAART. Moreover, microbial translocation is associated with insufficient reconstitution of CD4+T cells, and contributes to the pathogenesis of immunologic non-response. In a double-blind, randomised, placebo-controlled trial, we recently showed that, compared to placebo, 12 weeks treatment with probiotic Saccharomyces boulardii significantly reduced plasma levels of bacterial translocation (Lipopolysaccharide-binding protein or LBP) and systemic inflammation (IL-6) in 44 HIV virologically suppressed patients, half of whom (n = 22) had immun…

Òliba, Lechuza común (VER0000120)

Altres noms vulgars: Barn owl guttata (Anglès), Effraie des clochers guttata (Francès), Schleiereule-guttata (Alemany) Gabinet de Vertebrats (Departament de Zoologia), Facultat de Ciències Biològiques (Campus de Burjassot), C/ Doctor Moliner, s/n, Bloque B. 5é plant, Burjassot (Valencia). Armari: 2-2 Valencia

Rafael l. Ninyoles: Recorregut biogràfic i intel·lectual

2020

This article presents the biography and intellectual legacy of Valencian sociologist Rafael L. Ninyoles (1943- 2019). It reviews his formative itinerary, his early contributions to the field of the sociology of language, his latest contributions to the sociology of cities and cultural spaces, and his key involvement in the promoti-on and consolidation of the sociological study of Valencian society. The article includes a note on public acknowledgements to the author, plus an annex with a selective bibliography aimed at serving the interested reader and the posthumous diffusion of Ninyoles? oeuvre.

2021

Four drugs are currently approved for the treatment of Alzheimer’s disease (AD) by the FDA. Three of these drugs—donepezil, rivastigmine, and galantamine—belong to the class of acetylcholine esterase inhibitors. Memantine, a NMDA receptor antagonist, represents the fourth and a combination of donepezil and memantine the fifth treatment option. Recently, the gut and its habitants, its microbiome, came into focus of AD research and added another important factor to therapeutic considerations. While the first data provide evidence that AD patients might carry an altered microbiome, the influence of administered drugs on gut properties and commensals have been largely ignored so far. However, t…

Comparison of the intestinal microbiome of italian patients with multiple sclerosis and their household relatives

2021

Multiple sclerosis (MS) is a chronic immune-mediated disease of the central nervous system, caused by a combination of genetic and environmental factors. In recent years, a role in MS pathogenesis was assigned to the gut microbiota. However, different signatures of gut dysbiosis have been shown to depend on environmental factors, like diet and lifestyle. In this study, we compared the gut microbiome in MS patients and their household healthy relatives sharing lifestyle and environmental factors. Faecal metagenomic DNA was extracted and the V3–V4 regions of the conserved bacterial 16S ribosomal RNA gene were amplified and sequenced. While overall bacterial communities were similar, specific …

Evolved high aerobic capacity has context-specific effects on gut microbiota

2022

Publisher Copyright: Copyright © 2022 Hanhimäki, Watts, Koskela, Koteja, Mappes and Hämäläinen. Gut microbiota is expected to coevolve with the host's physiology and may play a role in adjusting the host's energy metabolism to suit the host's environment. To evaluate the effects of both evolved host metabolism and the environmental context in shaping the gut microbiota, we used a unique combination of (1) experimental evolution to create selection lines for a fast metabolism and (2) a laboratory-to-field translocation study. Mature bank voles Myodes glareolus from lines selected for high aerobic capacity (A lines) and from unselected control (C lines) were released into large (0.2 ha) outdo…

Diversity and composition of the microbiome associated with eggs of the Southern green stinkbug, Nezara viridula (Hemiptera: Pentatomidae).

2022

Although microbial communities of insects from larval to adult stage have been increasingly investigated in recent years, little is still known about the diversity and composition of egg-associated microbiomes. In this study, we used high-throughput amplicon sequencing and quantitative PCR to get a better understanding of the microbiome of insect eggs and how they are established using the Southern green stinkbug Nezara viridula (L.) (Hemiptera: Pentatomidae) as a study object. First, to determine the bacterial community composition, egg masses from two natural populations in Belgium and Italy were examined. Subsequently, microbial community establishment was assessed by studying stinkbug e…