Search results for "hair"
showing 10 items of 348 documents
Fine structure of sensilla during moulting inNeomysis integer (Leach) (Crustacea, Mysidacea)
1980
During the moulting cycle the sensory cells and the newly formed hair shaft remain connected to the old cuticular receptive apparatus of the sensillum by the elongated outer segments of the dendrites, which run through the exuvial space. A surface coat covering the outer dendritic segments protects them against the chemical influences of the exuvial fluid. The findings suggest that the receptors remain functional until ecdysis. This moulting type is considered to be a transitional form between the moulting types so far known.
Efficacy of three drugs for protecting against gentamicin-induced hair cell and hearing losses
2012
BACKGROUND AND PURPOSE Exposure to an ototoxic level of an aminoglycoside can result in hearing loss. In this we study investigated the otoprotective efficacy of dexamethasone (DXM), melatonin (MLT) and tacrolimus (TCR) in gentamicin (GM)-treated animals and cultures. EXPERIMENTAL APPROACH Wistar rats were divided into controls (treated with saline); exposed to GM only (GM); and three GM-exposed groups treated with either DXM, MLT or TCR. Auditory function and cochlear surface preparations were studied. In vitro studies of oxidative stress, pro-inflammatory cytokine mRNA levels, the MAPK pathway and caspase-3 activation were performed in organ of Corti explants from 3-day-old rats. KEY RESU…
Evidences of adaptive traits to rocky substrates undermine paradigm of habitat preference of the Mediterranean seagrass Posidonia oceanica
2015
AbstractPosidonia oceanica meadows are acknowledged as one of the most valuable ecosystems of the Mediterranean Sea. P. oceanica has been historically described as a species typically growing on mobile substrates whose development requires precursor communities. Here we document for the first time the extensive presence of sticky hairs covering P. oceanica seedling roots. Adhesive root hairs allow the seedlings to firmly anchor to rocky substrates with anchorage strength values up to 5.23 N, regardless of the presence of algal cover and to colonise bare rock without the need for precursor assemblages to facilitate settlement. Adhesive root hairs are a morphological trait common on plants li…
Cricket combined mechanoreceptors and kicking response
1977
1. Only those filiform hairs on the cerci ofGryllus, which are coupled with campaniform sensilla, show a) a thickening of the hair shaft at the height of the upper ring lamella of their sockets and b) a thin cuticular membrane, which surrounds their sockets. While thefiliform hairs themselves are deflected either parallel to the long axis of the cerci or perpendicular to it, thesockets of the filiform hairs may be deflected preferentially in the proximal and distal direction. 2. Spike potentials can be recorded from the sensory cells of the filiform hairs as long as these are deflected in a weak air current, but not during permanent deflection in strong air streams when they touch the inner…
Mosses as biomonitor of air pollution with analytes originating from tobacco smoke
2018
The aim of the carried out research was the assessment of the possibility to use a popular bioindicator - Pleurozium schreberi mosses as a biosensor of the air pollution in living quarters with the analytes originating from tobacco smoke. The moss bag method of active biomonitoring, popular in environmental studies, was applied; the method is based on exposing mosses collected in clean areas in the locations polluted with, for example, heavy metals. However, this experiment involved exposing mosses in living quarters, in which approximately 10 cigarettes were smoked daily (first room - kitchen). For the purpose of comparison, moss samples were also placed in another room (bedroom), which wa…
Choice and Practical Reasoning in Ancient Philosophy
2013
Ancient thinkers acknowledged that we are the sort of creatures that want things to be a certain way and can make efforts for them to become that way. In that sense, the ancients had a notion of volition. But it is not clear how they conceived of volition. The problem is partly historical. Some late ancient, notably Christian thinkers came to regard volition in a different way than earlier thinkers had done, seeing reason as a less powerful ability than Socrates did, and instead placing their hopes on the will, which they regarded as a separate and sovereign part of the soul. About these historical developments there is much debate and little agreement. The problem is also partly conceptual…
Dexamethasone treatment of naïve organ of Corti explants alters the expression pattern of apoptosis-related genes.
2009
Dexamethasone treatment of organ of Corti explants challenged with an ototoxic level of an inflammatory cytokine modulates NFkappaB signaling and the expression levels of both pro-and anti-apoptosis-related genes. It is not known if naïve organ of Corti explants will respond in a similar manner to treatment with a corticosteroid. This study examines the response of naïve organ of Corti explants to treatment with dexamethasone.Three-day-old rat organ of Corti explants were cultured for 1, 2, or 4 days. Four-day in vitro cultures were fixed, stained with FITC-phalloidin and hair cells were counted. ELISA was performed on 2-day cultures to determine the levels of phosphorylated nuclear factor …
Immuno-electron microscopic localization of the alpha(1) and beta(1)-subunits of soluble guanylyl cyclase in the guinea pig organ of corti.
2000
Guanylyl cyclases (GC) catalyze the formation of the intracellular signal molecule cyclic GMP from GTP. For some years it has been known that the heme-containing soluble guanylyl cyclase (sGC) is stimulated by NO and NO-containing compounds. The sGC enzyme consists of two subunits (alpha(1) and beta(1)). In the present study, the alpha(1) and beta(1)-subunits were identified in the guinea pig cochlea at the electron microscopic level using a post-embedding immuno-labeling procedure. Ultrathin sections of LR White embedded specimens were incubated with various concentrations of two rabbit polyclonal antibodies to the alpha(1)- and beta(1)-subunit, respectively. The immunoreactivity was visua…
Real-time detection of BRAF V600E mutation from archival hairy cell leukemia FFPE tissue by nanopore sequencing
2018
The MinION is a miniaturized high-throughput next generation sequencing platform of novel conception. The use of nucleic acids derived from formalin-fixed paraffin-embedded samples is highly desirable, but their adoption for molecular assays is hurdled by the high degree of fragmentation and by the chemical-induced mutations stemming from the fixation protocols. In order to investigate the suitability of MinION sequencing on formalin-fixed paraffin-embedded samples, the presence and frequency of BRAF c.1799T > A mutation was investigated in two archival tissue specimens of Hairy cell leukemia and Hairy cell leukemia Variant. Despite the poor quality of the starting DNA, BRAF mutation was su…