Search results for "hantavirukset"
showing 3 items of 3 documents
The impact of wildlife and environmental factors on hantavirus infection in the host and its translation into human risk
2023
Identifying factors that drive infection dynamics in reservoir host populations is essential in understanding human risk from wildlife-originated zoonoses. We studied zoonotic Puumala orthohantavirus (PUUV) in the host, the bank vole ( Myodes glareolus ), populations in relation to the host population, rodent and predator community and environment-related factors and whether these processes are translated into human infection incidence. We used 5-year rodent trapping and bank vole PUUV serology data collected from 30 sites located in 24 municipalities in Finland. We found that PUUV seroprevalence in the host was negatively associated with the abundance of red foxes, but this process did no…
Experimental ecology on the interaction between the Puumala hantavirus and its host, the bank vole
2006
Eva Kallio tutki väitöskirjatyössään ihmisissä myyräkuumetta aiheuttavan, Hantaviruksiin kuuluvan Puumala-viruksen ja sen isäntälajin metsämyyrän välistä vuorovaikutussuhdetta. Tutkimuksessa selvisi viruksen säilyvän infektiokykyisenä pitkään isännän ulkopuolellakin ja voivan tarttua myyrästä toiseen tai myyrästä ihmiseen ilman suoraa kontaktia. Kallio osoitti myös ensimmäisen kerran hantaviruksen olevan haitallinen isäntälajilleen.Kallion osoittaman Puumala-viruksen ja metsämyyrän välisen vuorovaikutussuhteen piirteet voivat osaltaan vaikuttaa ihmisten myyräkuume-epidemioiden ilmentymiseen. Uuden tiedon avulla pystytään myös yhä luotettavammin mallintamaan ja ennustamaan epidemioiden esiin…
Eco-epidemiology of tick- and rodent-borne pathogens in boreal forests
2017
Infectious diseases are amongst the ten major causes of human mortality worldwide, 60% of them being animal-borne. Variations of abiotic and biotic conditions are likely to modify the transmission of parasites and pathogens within reservoir species, and, as a consequence, alter the zoonotic risk for human. My thesis aims at elucidating the dynamics and mechanisms of the maintenance of ticks, tick-borne pathogens (TBPs) and the Puumala hantavirus (PUUV) in the reservoir host, the bank vole (Myodes glareolus, BV). In Northern Europe, tick-borne diseases are growing in importance to human because of the latitudinal expansion of the tick Ixodes ricinus. Field monitoring revealed that I. ricinus…