Search results for "harm avoidance"

showing 3 items of 13 documents

Replication of the association between CHRNA4 rs1044396 and harm avoidance in a large population-based sample.

2015

Harm avoidance is a personality trait characterized by excessive worrying and fear of uncertainty, which has repeatedly been related to anxiety disorders. Converging lines of research in rodents and humans point towards an involvement of the nicotinic cholinergic system in the modulation of anxiety. Most notably, the rs1044396 polymorphism in the CHRNA4 gene, which codes for the α4 subunit of the nicotinic acetylcholine receptor, has been linked to negative emotionality traits including harm avoidance in a recent study. Against this background, we investigated the association between harm avoidance and the rs1044396 polymorphism using data from N=1673 healthy subjects, which were collected …

genetics [Receptors Nicotinic]0301 basic medicineAdultMalemedicine.medical_specialtymedia_common.quotation_subjectContext (language use)Receptors NicotinicPolymorphism Single NucleotideNicotine03 medical and health sciences0302 clinical medicineHarm ReductionGermanymedicinePersonalityHumansPharmacology (medical)ddc:610PsychiatryBiological PsychiatryGenetic Association Studiesmedia_commonPharmacologybusiness.industrySmokinggenetics [Smoking]medicine.diseasePsychiatry and Mental healthNicotinic acetylcholine receptor030104 developmental biologyNicotinic agonistNeurologygenetics [Personality]AnxietyHarm avoidanceCholinergicFemaleNeurology (clinical)medicine.symptombusinessnicotinic acetylcholine receptor alpha4 subunit030217 neurology & neurosurgerymedicine.drugPersonalityEuropean neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology
researchProduct

Analysis of DRD2 Gene Polymorphism in the Context of Personality Traits in a Group of Athletes

2021

The presented study showed the relationship between dopamine receptor gene polymorphism and personality traits in athletes training in martial arts. Behavioral modulation resulting from a balance of the neurotransmitters dopamine and norepinephrine to inactivation of the dorsolateral prefrontal cortex and dysregulation of various pathways involved in attention and impulse control processes

media_common.quotation_subjectQH426-470ArticleReward systemDorsolateral Prefrontal CortexmedicineHumansPsychological testinggeneticsGenetics (clinical)media_commonPsychological TestsMartial artsPolymorphism GeneticbiologyAthletesReceptors Dopamine D2AddictionDopaminergicmedicine.diseasebiology.organism_classificationD2 receptorathletesReward dependencepersonality traitsHarm avoidancedopaminePsychologyClinical psychologyPersonalityGenes
researchProduct

A meta-analysis of temperament and character dimensions in patients with mood disorders: Comparison to healthy controls and unaffected siblings

2016

Background Cloninger's psychobiological model of personality has been extensively applied to subjects affected by mood disorders (MOOD). However, most studies are widely heterogeneous in terms of sample size, methods of assessment, and selection of participants. Methods We conducted a systematic review of literature and a random effects meta-analysis of studies comparing at least two of the following groups: (a) adults with a primary MOOD diagnosis (Bipolar Disorder (BP) or major depressive disorder (MDD)), (b) their unaffected siblings (SIB) or (c) healthy subjects (HS), and reporting quantitative results from the Tridimensional Personality Questionnaire (TPQ) or the Temperament and Charac…

medicine.medical_specialtyCharacterBipolar DisorderPersonality InventoryTraitTridimensional Personality QuestionnaireNO03 medical and health sciences0302 clinical medicineHarm ReductionmedicineHumansPsychiatryTemperamentDepressive Disorder MajorDepressionMood DisordersSiblingsCooperativenessNovelty seekingmedicine.diseaseTemperament Character Depression Mood disorders Bipolar Disorder Trait State030227 psychiatryClinical PsychologyMoodReward dependenceMood disordersPsychiatry and Mental HealthCase-Control StudiesHarm avoidanceRegression AnalysisTemperament and Character InventoryPsychologyBipolar Disorder; Character; Depression; Mood disorders; State; Temperament; Trait; Psychiatry and Mental Health; Clinical Psychology030217 neurology & neurosurgeryStateClinical psychology
researchProduct