Search results for "hazard"
showing 10 items of 1517 documents
Mapping and assessing coastal resilience in the Caribbean region
2015
Assessing the vulnerability and resilience to coastal hazards is a critical worldwide issue, especially for hurricane-prone coastal regions such as the Caribbean. However, the development of a useful metric for vulnerability and resilience assessment has a lot of challenges. Cartography and GIS analysis can contribute effectively to the solution of the issue by integrating natural and human data layers for assessment, mapping, and visualization. This paper uses the new Resilience Inference Measurement (RIM) model to assess the resilience of 25 countries in the Caribbean region to hurricanes. The RIM indices of the countries were computed using three variables representing three dimensions: …
A Nomogram-Based Prognostic Model for Advanced Hepatocellular Carcinoma Patients Treated with Sorafenib: A Multicenter Study
2021
Simple Summary Accurate prognostic systems capable of predicting the survival of patients with advanced hepatocellular carcinoma undergoing Sorafenib therapy are still lacking. The search for the ideal predictive tool for survival and drug response is justified by the recent availability of several other drugs effective for these patients, licensed as first- and second-line treatment, other than reducing adverse events and costs. In this study, we aimed to identify simple demographic and clinical parameters able to predict survival and Sorafenib response in a large multicenter cohort. In this study, we showed that patient’s general status, liver function and damage laboratory parameters and…
The multidimensional prognostic index (MPI) for the prognostic stratification of older inpatients with COVID-19: A multicenter prospective observatio…
2021
Background: The topic of prognosis in COVID-19 research may be important in adopting appropriate clinical decisions. Multidimensional prognostic index (MPI) is a frailty assessment tool widely used for stratifying prognosis in older people, but data regarding inpatients, affected by COVID-19, are not available. Objectives: To evaluate whether MPI can predict in-hospital mortality and the admission to intensive care unit (ICU) in older inpatients hospitalized for COVID-19 infection. Methods: In this longitudinal, Italian, multi-center study, older patients with COVID-19 were included. MPI was calculated using eight different domains typical of comprehensive geriatric assessment and categoriz…
Computational issues in fitting joint frailty models for recurrent events with an associated terminal event.
2020
Abstract Background and objective: Joint frailty regression models are intended for the analysis of recurrent event times in the presence of informative drop-outs. They have been proposed for clinical trials to estimate the effect of some treatment on the rate of recurrent heart failure hospitalisations in the presence of drop-outs due to cardiovascular death. Whereas a R-software-package for fitting joint frailty models is available, some technical issues have to be solved in order to use SASⓇ 1 software, which is required in the regulatory environment of clinical trials. Methods: First, we demonstrate how to solve these issues by deriving proper likelihood-decompositions, in particular fo…
Probabilistic characterization of flood hazard using bivariate analysis based on copulas
2014
This study presents an innovative approach to obtain flood hazard maps where hydrological input (synthetic flood design event) to a 2D hydraulic model has been defined by generating flood peak discharges and volumes from a bivariate statistical analysis, through the use of copulas. Synthetic hydrographs were generated by means two different approaches: an indirect one, where rainfall were generated by a stochastic bivariate rainfall generator to be entered a distributed conceptual rainfall-runoff model that consisted of a soil moisture routine and a flow routing routine; and a direct one, where stochastic generation of flood peaks and flow volumes have been obtained via copulas, which descr…
Key EU DEMO plant and building layout criteria
2021
Abstract An early attention to the layout of both plant site and its buildings is essential in a complex plant under preliminary design as DEMO in order to meet the assigned targets, namely i) the licensing requirements ii) a good availability in delivery electricity to the grid. The layout definition has to follow several criteria that become more complex and stringent for nuclear buildings, e.g. functional, maintenance, fire protection, safety, human factors, shielding, and remote handling. The criterion As Low As Reasonable Achievable, with respect to the dose to the staff, has to be applied in design, operation, maintenance and decommissioning phases. The tokamak building, where several…
A New Aid Modality for Africa: Old Age Cash Transfers
2010
This paper examines the issue of foreign aid and cash transfers to individuals in low-income economies typically found in Africa. Old-age conditional cash transfers and new mobile banking technology can cope with the well-documented problems related to moral hazard and high transaction costs with such policy interactions. Cash transfers can stimulate old and retired individuals’ demand for the consumption goods and services, and thereby affect product prices and wages. Developing economies being characterised by underemployment and gross substitution between consumption and leisure, these transfers can stimulate the labour supply and increase capacity utilisation and the production of labou…
Food choices and environmental responsibility – protect the Baltic Sea
2012
‘The Baltic environment, food and health: from habits to awareness – FOODWEB’ is a project that aims to raise public awareness about the links between food quality and its origin, focusing on the Baltic Sea and its surroundings. Cultivation of food for humans and related production activities can impact negatively on the Baltic Sea, and aquatic food products from the Baltic Sea may cause problems to humans as a result of toxins in the marine environment. This is a circular problem in the Baltic ecosystem. The project is a part of Central Baltic IVA Programme 2007- 2013. Finland, Estonia and Latvia take part in the Foodweb-project. The population is projected to grow in Finland and decrease …
Rationale, design and methods of CTCA-PRORECAD (Computed Tomography Coronary Angiography Prognostic Registry for Coronary Artery Disease): a multicen…
2013
PURPOSE: This study was done to assess the prognostic value of computed tomography coronary angiography (CTCA) in a large multicentre population of patients with suspected coronary artery disease (CAD) and, in particular, its incremental value compared with traditional methods for risk stratification. MATERIALS AND METHODS: This is a retrospective observational study that began in January 2003 conducted on patients with suspected CAD assessed with CTCA on the basis of symptoms (chest pain, dyspnoea) and/or abnormal or equivocal stress test and/or a high cardiovascular risk profile. The participating centres will provide data obtained with CTCA performed with 16-slice or higher equipment. Ex…
Investor Protection and Business Creation
2003
We study the effects of investor protection on the availability of external finance, entrepreneurship, and creation of new firms in an equilibrium search model of private capital markets. In addition to search frictions, we examine contract frictions, specifically interim and ex post moral hazard problems stemming from entrepreneurs' possibilities to expropriate financiers. In our model, the government chooses the level of investor protection that determines the transferability of match surplus between entrepreneurs and financiers. The results indicate that anything that increases (decreases) entrepreneurship also increases (decreases) the creation of start-ups. The effect of investor prote…