Search results for "heme"
showing 10 items of 1104 documents
Calf Blood Compound (CFC) and Homeopathic Drug Induce Differentiation of Primary Human Skeletal Muscle Cells.
2019
AbstractThe use of injections to treat structural muscle injuries is controversially discussed. In our controlled in vitro study, we investigated the biological impact of Actovegin and Traumeel alone and in combination on primary human skeletal muscle cells. Cells were characterized by immunofluorescence staining for myogenic factor 5 (Myf5) and MyoD, and cultured with or without Actovegin and / or Traumeel. The effects of these agents were assayed by cell viability and gene expression of the specific markers MyoD, Myf5, neural adhesion molecule (NCAM), and CD31. Myotube formation was determined by myosin staining. Neither Actovegin nor Traumeel showed toxic effects or influenced cell viabi…
Syntax and conversation in aphasia. A strategic restrictive use of Spanish and Catalan connector QUE by aphasic speakers.
2009
Oral conversational data are deemed to be a relevant empirical source when it comes to formulating and supporting hypotheses about cognitive processes involved in aphasic linguistic production. With this assumption in mind, free conversational uses of the Spanish and Catalan connector QUE by fluent and non-fluent aphasic speakers are examined by contrasting them with normal speakers' (i.e. conversational partners') productions. Strictly ungrammatical uses in aphasic speakers are practically non-existent in free conversation. Nevertheless, this data permits one to characterize the aphasic production of the morpheme QUE as restrictive--to different degrees--with respect to normal production. …
Brief depression among patients in general practice
1994
Depression with substantial psychosocial impairment, but not qualifying as depressive disorder according to the standard diagnostic manuals, is frequent among primary care patients. Recurrent brief depression (RBD) is a diagnostic category intended to identify a major proportion of this group of patients. The WHO study on "Psychological Problems in Primary Health Care" was used as a vehicle to estimate the proportion of patients with this diagnosis and to evaluate the validity of this diagnosis as well as of alternative concepts of brief depression with multiple episodes. This study applies a two-stage sampling scheme; 300 patients also underwent an additional interview tailored for variant…
Immediate transfer of synesthesia to a novel inducer.
2009
In synesthesia, a certain stimulus (e.g. grapheme) is associated automatically and consistently with a stable perceptual-like experience (e.g. color). These associations are acquired in early childhood and remain robust throughout the lifetime. Synesthetic associations can transfer to novel inducers in adulthood as one learns a second language that uses another writing system. However, it is not known how long this transfer takes. We found that grapheme-color associations can transfer to novel graphemes after only a 10-minute writing exercise. Most subjects experienced synesthetic associations immediately after learning a new Glagolitic grapheme. Using a Stroop task, we provide objective ev…
Liraglutide Reduces Oxidative Stress And Restores Heme Oxygenase-1 and Ghrelin Levels in Patients with Type 2 Diabetes: A Prospective Pilot Study
2014
Abstract Context: Liraglutide is a glucagon-like peptide-1 analog and glucose-lowering agent whose effects on cardiovascular risk markers have not been fully elucidated. Objective: We evaluated the effect of liraglutide on markers of oxidative stress, heme oxygenase-1 (HO-1), and plasma ghrelin levels in patients with type-2 diabetes mellitus (T2DM). Design and Setting: A prospective pilot study of 2 months' duration has been performed at the Unit of Diabetes and Cardiovascular Prevention at University of Palermo, Italy. Patients and Intervention(s): Twenty subjects with T2DM (10 men and 10 women; mean age: 57 ± 13 y) were treated with liraglutide sc (0.6 mg/d for 2 wk, followed by 1.2 mg/d…
On the complementarity of holistic and analytic approaches to performance assessment scoring.
2019
BACKGROUND A holistic approach to performance assessment recognizes the theoretical complexity of multifaceted critical thinking (CT), a key objective of higher education. However, issues related to reliability, interpretation, and use arise with this approach. AIMS AND METHOD Therefore, we take an analytic approach to scoring students' written responses on a performance assessment. We focus on the complementarity of holistic and analytic approaches and on whether theoretically developed analytical scoring rubrics can produce sub-scores that may measure the 'whole' performance in a holistic assessment. SAMPLE We use data from the Wind Turbines performance assessment, developed in the iPAL p…
European perspective on the 2015 American Thyroid Association Management Guidelines for Adult Patients with Thyroid Nodules and Differentiated Thyroi…
2018
The American Thyroid Association (ATA) management guidelines for patients with thyroid nodules and differentiated thyroid cancer (DTC) are highly influential practice recommendations. The latest revision appeared in 2015 ("ATA 2015"). These guidelines were developed predominantly by North American experts. European experts frequently have different perspectives, given epidemiological, technological/methodological, practice organization, and medicolegal differences between the respective regions.Divergent viewpoints were the focus of an invited symposium organized by the European Association of Nuclear Medicine involving 17 European thyroidologists, four ATA Guidelines Taskforce members, and…
A comprehensive classification of craniofacial fractures: postmortem and clinical studies with two- and three-dimensional computed tomography.
2002
Abstract A comprehensive classification of midfacial/craniofacial fractures, based on two- and three-dimensional computed tomography (2D and 3D-CT) is presented. We performed a postmortem analysis of 24 patients who had died from trauma with signs of craniofacial fractures, based on 2D and 3D-CT studies with pathoanatomical findings. In addition, CT findings for 100 patients with craniofacial injuries requiring an emergency CT were correlated with surgical findings and follow-up results. On the basis of the analysis of a total of 377 fractures a classification system is proposed. The system is based on the use of the AO/ASIF (Arbeitsgemeinschaft fur Osteosynthesefragen/Association for the S…
Editorial Comment—Is Heme Oxygenase-1 a Causal Player for Plaque Stability?
2005
Inflammatory mechanisms play an important role in all stages of the atherosclerotic process.1 Various studies implicate that certain infectious agents represent candidates that trigger these inflammatory responses.2 An association of viral infection with atherosclerosis was first reported in the 1970s, when experimental infection of germ-free chickens with an avian herpes virus was found to produce arterial disease.3 Although several infectious pathogens have been detected within the atherosclerotic plaque, including Chlamydia pneumoniae , Cytomegalovirus, and Helicobacter pylori , the precise role of these pathogens in causing atherosclerosis or in aggravating the atherosclerotic process r…
Reklāma kā tēma kulturoloģijā
2019
Diplomdarba tēma - Reklāma kā tēma kulturoloģijā. Pētījuma ievadā pamatota temata izvēle un aktualitāte, kas balstās uz jauniešu izglītošanu par reklāmas būtību un tās lomu sabiedrības vērtību sistēmas ietekmēšanā, uzskatu veidošanā. Darbā izpētīta teorētiskā informācijas bāze par reklāmu. Izpētītas un sistematizētas reklāmas definīcijas, mērķi, veidi un uzdevumi, aplūkota reklāmas vēsturiskā attīstība no pirmsākumiem līdz tās jaunajai realitātei digitālajā laikmetā, sniegts ieskats reklāmas ētikā, aplūkojot tās lomu mūsdienu patērējtājsabiedrībā, apskatīti svarīgākie reklāmas psiholoģijas aspekti un to ietekme uz sabiedrības un indivīda apziņu. Pētījumā apzināti reklāmas izpētes un veidoša…