Search results for "hemorrhage"
showing 3 items of 503 documents
Pharmacokinetics of new oral anticoagulants: implications for use in routine care
2018
Introduction: Since 2008, new oral anticoagulants (NOACs) have been approved for the prevention of venous thromboembolism (VTE) in patients receiving hip or knee replacement surgery, prevention of stroke and systemic embolism in patients with non-valvular atrial fibrillation (NVAF), treatment of deep vein thrombosis (DVT), and pulmonary embolism (PE). Premarketing randomized clinical trials (RCTs) of NOACs demonstrated their non-inferiority in terms of efficacy vs. warfarin (traditional oral anticoagulant–TOA), with lower risk of serious adverse drug reactions, especially cerebral hemorrhages. In clinical practice, pharmacokinetic aspects of NOACs have to be carefully taken into account to …
La influencia de la técnica quirúrgica en la hemorragia postamigdalectomía
2022
La complicación más frecuente de la amigdalectomía extracapsular (AE) es la hemorragia postamigdalectomía (HPA). Los factores relacionados con esta son diversos, entre los que se encuentra la técnica quirúrgica con la que se lleva a cabo. Se distinguen las técnicas frías y calientes. Entre sus indicaciones se encuentran las infecciones amigdalares de repetición, las complicaciones derivadas de estas amigdalitis y pacientes pediátricos con trastornos respiratorios del sueño (TRS). En este último grupo, una alternativa terapéutica es la amigdalectomía intracapsular (AI). Se distinguen dos tipos de HPA: primaria, que ocurre durante las primeras 24 horas, y secundaria (HPAt), que ocurre tras la…
Intracranial Venous Alteration in Patients With Aneurysmal Subarachnoid Hemorrhage: Protocol for the Prospective and Observational SAH Multicenter St…
2022
BackgroundArterial vasospasm has been ascribed as the responsible etiology of delayed cerebral infarction in patients with aneurysmal subarachnoid hemorrhage (aSAH), but other neurovascular structures may be involved. We present the protocol for a multicenter, prospective, observational study focused on analyzing morphological changes in cerebral veins of patients with aSAH.Methods and AnalysisIn a retrospective arm, we will collect head arterial and venous CT angiograms (CTA) of 50 patients with aSAH and 50 matching healthy controls at days 0–2 and 7–10, comparing morphological venous changes. A multicenter prospective observational study will follow. Patients aged ≥18 years of any gender …