Search results for "heptacosane"
showing 3 items of 3 documents
Volatile components from aerial parts of centaurea spinosociliata seenus ssp. Cristata (Bartl.) Dostál and centaurea spinosociliata seenus ssp. spino…
2010
The paper reports on the volatile components oil from aerial parts of two Asteraceae growing wild in Croatia: Centaurea spinosociliata ssp. cristata (syn. Centaurea cristata Bartl. subsp. rabenhorstiana (Sch.Bip.) Nyman) (CSC) and C. spinosociliata ssp. spinosociliata (CSS). The volatile components were obtained by hydrodistillation from selected plants and were determined by the GC-MS system on two fused-silica capillary columns of different polarity. The oil content was 0.08 % (CSC) and 0.07 % (CSS) on a dry weight basis. Altogether 73 compounds were identified accounting for 90.8 % (CSC) and 92.8 % (CSS) of the total oil, that were characterized mainly by hydrocarbons (37.9 %; 30.4 %), s…
Volatile components from flowers of Centaurea nicaeensis All., C. parlatoris Helder, C. solstitialis L., ssp. schouwii (DC.) Dostàl wild growing in S…
2008
The volatile constituents of the flowerheads of Centaurea nicaeensis All., C. parlatoris Helder and C. solstitialis L. ssp. schouwii (DC.) Dostal were extracted by hydrodistillation and analysed by GC and GC-MS. Altogether 113 components were identified. Fatty acids and hydrocarbons were the most abundant components in the oils. Caryophyllene and caryophyllene oxide were the main compounds of the sesquiterpene fraction. The study on the biological activity of the oils shows no significant activity.
Phytol and Heptacosane Are Possible Tools to Overcome Multidrug Resistance in an In Vitro Model of Acute Myeloid Leukemia
2022
Drug resistance is the ability of cancer cells to gain resistance to both conventional and novel chemotherapy agents, and remains a major problem in cancer therapy. Resistance mechanisms are multifactorial and involve more strictly pharmacological factors, such as P-glycoprotein (P-gp) and biological factors such as inhibitor of apoptosis proteins (IAPs) and the nuclear factor-kappa B (NF-κB) pathway. Possible therapeutic strategies for the treatment of acute myeloid leukemia (AML) have increased in recent years; however, drug resistance remains a problem for most pa-tients. Phytol and heptacosane are the major compounds of Euphorbia intisy essential oil (EO) which were demonstrated to inhi…