Search results for "heroin"
showing 10 items of 41 documents
Exercise as an Adjuvant Intervention in Opiate Dependence
2013
We read with interest the article by Weinstock et al. in whichthe authors propose exercise as an adjuvant intervention inopiate agonist treatment based on current research findings(1).The use of an opiate agonist, such as buprenorphine, butmainly, methadone, for the treatment of opiate dependenceis currently an effective therapy for this type of addiction.The main benefits of this treatment occur through a relieffrom craving narcotic drugs, a temporally suppression ofwithdrawal symptoms, and by blocking the euphoric effectsof opiates (2). Unfortunately, patients needing treatment foropiatedependenceoftenfaceavarietyofco-occurringissues,suchashepatitisBandCvirusesorhumanimmunodeficiencyvirus (H…
Piccole città per quarantenni. Sul senso di sé nella scrittura storiografica, in margine a un libro di Vanessa Roghi
2019
Starting from an analysis of Vanessa Roghi's recent book, Piccole città, we focus on the link between historiographic writing and autobiography. In particular, it analyzes the way this link changed at the end of the twentieth century, when political categories that had determined identities, even of historians, for more than a century, have finished. Since then, issues considered "private" have emerged in the public debate and in the historiographic debate, as happened for example with drug addiction, at the centre of Roghi's book.
Italian Heroines: Literature, Gender, and the Construction of the Nation
2019
Scholarship on Italian nationhood has historically focused on heroes rather than on heroines, in line with the established gendered dialectical relationship between the female nation (who nurtures those who fight for her), and the male patriot, who both adores and possesses her. However, it is argued that Italian literary heroines prove at least as productive as heroes, if not more, when it comes to generating alternative views on the nation. This essay offers an introduction to a themed issue that aims to fill this scholarly gap in relation to ideas about the Italian nation and nationhood.
Saliva testing after single and chronic administration of dihydrocodeine.
2001
In the present study, concentrations of dihydrocodeine and its metabolites in saliva and serum were compared after single low-dose and chronic high-dosage administration of the drug. In the first investigation, blood and saliva were collected periodically from six subjects after oral administration of 60 mg dihydrocodeine. In the second study, 20 subjects on oral dihydrocodeine maintenance provided single samples of blood and saliva simultaneously. Serum protein binding of salivary analytes and their recovery from the adsorbing material of the collection device as well as pH values of saliva samples were determined. The fluids were analyzed for dihydrocodeine and the major metabolites by hi…
Preliminary Practical Findings on Drug Monitoring by a Transcutaneous Collection Device
1996
A noninvasive and nonocclusive skin patch (Sudormed™) was investigated for the systematic collection of drugs of abuse over a period of several days. First, the applicability and user friendliness were tested by volunteers. The permeability of the polyurethane dressing from the outside to the inside for an aqueous solution was shown by incubating the outside layer with Rhodamine B. No fluorescence could be detected in the cotton pad beneath. A single dose experiment using theophylline as a model compound showed that there was a delay in time before the substance could be determined in the pad. The drug content decreased with increasing time of patch application. When eight volunteers partic…
From political controversy to a technical problem? Fifteen years of opioid substitution treatment in Finland
2013
Abstract Background The aim of the article is to analyze changes in opioid substitution treatments (OST) in Finland. OST spread in Finland in the late 1990s and early 2000s (Phase 1). Since then, OST has become an integrated part of Finnish drug policy and is provided in various substance abuse treatment units as well as in municipal health centers (Phase 2). Methods The paper analyses the policy around the implementation of opioid substitution treatment in Finland, focusing on identifying the key factors and the relations between them that have contributed to the implementation of OST in Finland. Results OST has become accepted in Finland during the past ten years as a crucial element of a…
Occurrence and removal of drugs of abuse in Wastewater Treatment Plants of Valencia (Spain)
2014
The occurrence of 8 drugs of abuse and metabolites in the influent and effluent of the 3 Wastewater Treatment Plants (WWTP) that treat wastewater from Valencia was studied in 2011, 2012 and 2013. Target drugs except 6-monoacetylmorphine (6-ACMOR) were detected in 100% of the influents. The WWTPs eliminate cocaine (COC), amphetamine (AMP), methamphetamine (MAMP) and 11-nor-9-carboxy-Δ9-tetrahydrocannabinol (THC-COOH). Benzoylecgonine (BECG) was also efficiently eliminated (93-98%), whereas 3,4-methylenedioxymethamphetamine (MDMA) presented removal rates of 32-57% and ketamine (KET) was not eliminated. The most consumed illicit drugs, according to the estimated concentrations of each compound…
Patrones de consumo y variables de personalidad en drogodependientes a tratamiento
2012
El objetivo de este trabajo es analizar la relación entre factores de personalidad y consumo de sustancias. Específi camente se busca analizar la impulsividad y la búsqueda de sensaciones como variables de personalidad derivadas de modelos psicobiológicos de personalidad, así como el autocontrol, para examinar su relación con los patrones de consumo de drogas. En el trabajo se exploran las características diferenciales en términos de personalidad en pacientes adictos a heroína y en pacientes adictos a cocaína, así como en otro grupo de consumidores que puede merecer especial atención, como es el caso de los antiguos consumidores de heroína que ahora son adictos a la cocaína. La muestra está…
Loss of spatial learning in a patient with topographical disorientation in new environments
2003
The case is described of a patient who, following cerebral hypoxia, developed severe difficulty in orienting himself in new environments in the context of a mild global amnesic syndrome. Some episodes he related suggested that his main difficulty was remembering the spatial/directional value of landmarks he recognised. A neuroradiological examination documented severe bilateral atrophy of the hippocampi associated with atrophic changes in the cerebral hemispheres, most marked in the dorsal regions. Neuropsychological and experimental evaluation showed a severe deficit of spatial learning with substantially preserved ability to learn verbal and visual-object information. He was also virtuall…
Effect of adolescent exposure to MDMA and cocaine on acquisition and reinstatement of morphine-induce CPP
2007
It is well known that an elevated percentage of ecstasy users also consume cocaine. Recently, it has been reported that a high frequency of heroin smokers first consumed heroin under the effects of ecstasy with the hope of reducing the stimulant effects of the latter drug. The aim of the present study was to evaluate the effect of exposure to MDMA and cocaine during adolescence on morphine-induced conditioned place preference (CPP) and reinstatement in adulthood. In the first experiment, adolescent mice were exposed to six injections of MDMA and three weeks later their response to the reinforcing properties of 40 mg/kg of morphine was evaluated using the CPP paradigm. All the treatment grou…