Search results for "high-intensity"

showing 10 items of 63 documents

High-Intensity Focused Ultrasound- and Radiation Therapy-Induced Immuno-modulation: Comparison and Potential Opportunities

2017

In recent years, high-intensity focused ultrasound (HIFU) has emerged as a new and promising non-invasive and non-ionizing ablative technique for the treatment of localized solid tumors. Extensive pre-clinical and clinical studies have evidenced that, in addition to direct destruction of the primary tumor, HIFU-thermoablation may elicit long-term systemic host anti-tumor immunity. In particular, an important consequence of HIFU treatment includes the release of tumor-associated antigens (TAAs), the secretion of immuno-suppressing factors by cancer cells and the induction of cytotoxic T lymphocyte (CTL) activity. Radiation therapy (RT) is the main treatment modality used for many types of tu…

0301 basic medicinePathologymedicine.medical_specialtyRadiology Nuclear Medicine and ImagingAcoustics and Ultrasonicsmedicine.medical_treatmentBiophysicsImmunomodulation03 medical and health sciences0302 clinical medicineImmune systemNeoplasmsmedicineBystander effectHumansCancerChemotherapyRadiological and Ultrasound Technologybusiness.industryCancermedicine.diseasePrimary tumorThermal ablationHigh-intensity focused ultrasoundRadiation therapyImmuno-therapyRadiation therapyTumor vaccine030104 developmental biologyBiophysicHigh-intensity focused ultrasound030220 oncology & carcinogenesisCancer cellCancer researchHigh-Intensity Focused Ultrasound AblationAnti-tumor immunitybusinessAnti-tumor immunity; Cancer; High-intensity focused ultrasound; Immuno-therapy; Radiation therapy; Thermal ablation; Tumor vaccine
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Impact of a 4-Week Intensified Endurance Training Intervention on Markers of Relative Energy Deficiency in Sport (RED-S) and Performance Among Well-T…

2020

Cyclists often apply block periodization to high training volumes in meso- and macrocycles to optimize training adaptation and to prepare for competition. Body mass influences performance in many sports, including endurance disciplines, and conditions related to the syndrome Relative Energy Deficiency in Sports (RED-S) such as metabolic adaptations and premature osteoporosis have also been reported in male cyclists. This study aimed to determine how a 4-week mesocycle of intensified endurance training designed to increase performance, would affect markers of RED-S in well-trained male cyclists. Twenty-two participants (age: 33.5 ± 6.6 years, height: 181.4 ± 5.2 cm, weight: 76.5 ± 7.4 kg, pe…

AdultMale0301 basic medicineVDP::Medisinske Fag: 700::Idrettsmedisinske fag: 850::Treningslære: 851Endocrinology Diabetes and Metabolismmale cyclistsOsteoporosisenergy availability030209 endocrinology & metabolismAthletic PerformanceHigh-Intensity Interval Traininglcsh:Diseases of the endocrine glands. Clinical endocrinologyhormonal responseInterval training03 medical and health sciencesEndocrinology0302 clinical medicineAnimal scienceEndurance trainingHumansRelative Energy Deficiency in SportMedicineProspective Studiesresting metabolic rateTestosteroneOriginal Researchlcsh:RC648-665Triiodothyroninebusiness.industryendurance athletesVO2 maxVDP::Medisinske Fag: 700::Idrettsmedisinske fag: 850medicine.diseaseEndurance Training030104 developmental biologytestosteroneBasal metabolic ratetraining interventionBasal MetabolismbusinessBiomarkersRelative energyFrontiers in Endocrinology
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Predicting the Unknown and the Unknowable. Are Anthropometric Measures and Fitness Profile Associated with the Outcome of a Simulated CrossFit® Compe…

2021

The main objective of this research was to find associations between the outcome of a simulated CrossFit® competition, anthropometric measures, and standardized fitness tests. Ten experienced male CrossFit® athletes (age 28.8 ± 3.5 years

AdultMaleFunctional trainingHealth Toxicology and MutagenesisPhysical fitnesslcsh:MedicineSquatBivariate analysisBench pressArticlehigh-intensity functional training03 medical and health sciences0302 clinical medicineStatisticsHumanscross-trainingMuscle Strength030212 general & internal medicineExerciseMathematicsCross-trainingbusiness.industrylcsh:RPublic Health Environmental and Occupational Health030229 sport sciencesAnthropometryTest (assessment)functional fitnessAthletesPhysical FitnessExercise TestathletebusinessperformanceInternational Journal of Environmental Research and Public Health
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Effects of Combined Strength and Sprint Training on Lean Mass, Strength, Power and Sprint Performance in Masters Road Cyclists

2017

Del Vecchio, L, Stanton, R, Reaburn, P, Macgregor, C, Meerkin, J, Villegas, J, and Korhonen, MT. Effects of combined strength and sprint training on lean mass, strength, power, and sprint performance in masters road cyclists. J Strength Cond Res 33(1): 66-79, 2019-Strength and sprint-training exercises are integral part of training in many younger endurance cyclists to improve cycling efficiency and sprinting ability. This study was undertaken to examine whether muscle and performance characteristics could be improved in endurance-trained masters cyclist by adding strength and sprint-training stimuli into their training regimen. Twenty-five masters road cyclists were assigned to a combined …

AdultMaleexplosive strengthmedicine.medical_specialtycyclists (athletes)educationIsometric torqueHamstring Muscles030209 endocrinology & metabolismPhysical Therapy Sports Therapy and RehabilitationAthletic PerformanceHigh-Intensity Interval TrainingveteraaniurheiluQuadriceps Muscle03 medical and health sciences0302 clinical medicineTime trialkilpapyöräilijätstrength trainingHumansMedicineOrthopedics and Sports MedicineMuscle Strengthta315business.industrynopeusvoimaWork (physics)Resistance Training030229 sport sciencesGeneral MedicineMiddle AgedBicyclingSprint trainingTorqueSprintlihasmassamuscle massBody CompositionLean body massPhysical therapyveteran sportsaikuisurheiluvoimaharjoittelubusinessCyclingHigh-intensity interval traininghuman activities
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Six Sessions of Sprint Interval Training Improves Running Performance in Trained Athletes

2017

Abstract Koral, J, Oranchuk, DJ, Herrera, R, and Millet, GY. Six sessions of sprint interval training improves running performance in trained athletes. J Strength Cond Res 32(3): 617–623, 2018—Sprint interval training (SIT) is gaining popularity with endurance athletes. Various studies have shown that SIT allows for similar or greater endurance, strength, and power performance improvements than traditional endurance training but demands less time and volume. One of the main limitations in SIT research is that most studies were performed in a laboratory using expensive treadmills or ergometers. The aim of this study was to assess the performance effects of a novel short-term and highly acces…

AdultMalemedicine.medical_specialtyAdolescentErgometry030209 endocrinology & metabolismPhysical Therapy Sports Therapy and RehabilitationAthletic PerformanceHigh-Intensity Interval TrainingInterval trainingRunningpower03 medical and health sciencesYoung Adult0302 clinical medicineTime trialPaired samplesEndurance trainingMedicinerepeated sprintsHumansOrthopedics and Sports MedicineFatigueTime to exhaustionOriginal Researchendurancebiologybusiness.industryAthletescapacityPower performance030229 sport sciencesGeneral Medicinebiology.organism_classificationfieldSprintAthletesPhysical therapyExercise TestPhysical EnduranceFemalebusinessmetabolismJournal of Strength and Conditioning Research
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Leisure-time cross-country skiing is associated with lower incidence of type 2 diabetes:A prospective cohort study

2019

Background Cross-country skiing is associated with reduction in risk of adverse vascular outcomes, but its association with type 2 diabetes is uncertain. We aimed to assess the associations between leisure-time cross-country skiing habits and incident type 2 diabetes. Methods We analysed the data of 2483 middle-aged men with no history of diabetes at baseline in the Kuopio Ischemic Heart Disease prospective study. The frequency, average duration, and intensity of leisure cross-country skiing were assessed at baseline using a 12-month physical activity questionnaire. Hazard ratios (HRs) (95% CIs) for type 2 diabetes were estimated. Results During a median follow-up of 21.6 years, 539 men dev…

AdultMalemedicine.medical_specialtyEndocrinology Diabetes and Metabolismphysical activity030209 endocrinology & metabolismType 2 diabetes030204 cardiovascular system & hematologyMetabolic equivalent03 medical and health sciencesLeisure Activities0302 clinical medicineEndocrinologySkiingInternal medicineDiabetes mellitusEpidemiologyInternal MedicineHumansMedicineProspective StudiesProspective cohort studyExerciseFinlandbusiness.industryIncidenceHazard ratioMiddle AgedPrognosismedicine.diseaseDiabetes Mellitus Type 2high-intensity exercise trainingFemaletype 2 diabetesbusinessRisk assessmenthuman activitiescross-country skiingFollow-Up StudiesCohort study
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Effects of HRV-Guided vs. Predetermined Block Training on Performance, HRV and Serum Hormones

2017

AbstractThe aim of this study was to compare heart rate variability -guided (HRVG) and predetermined (PD) block periodization of high intensity aerobic training (HIT). Endurance performance, neuromuscular performance, heart rate variability (HRV) and serum hormone concentrations were measured before, in the middle and after the 8-week training period in 24 endurance trained males. Both groups improved significantly maximal treadmill velocity (Vmax) (p<0.001) and 3000 m running performance (HRVG; p<0.001 and PD; p=0.001). The relative changes in Vmax and countermovement jump were significantly greater in HRVG (p<0.05). Nocturnal heart rate decreased in both groups (p<0.01), but H…

AdultMalemedicine.medical_specialtyHydrocortisoneblock periodizationPhysical Therapy Sports Therapy and RehabilitationAthletic PerformanceHigh-Intensity Interval Training030204 cardiovascular system & hematologyInterval trainingYoung Adult03 medical and health sciences0302 clinical medicineHeart RateInternal medicineautonominen hermostoHeart ratemedicineHumansAerobic exerciseHeart rate variabilityTestosteroneOrthopedics and Sports MedicineMuscle StrengthTreadmillMuscle SkeletalHydrocortisoneAnthropometrybusiness.industryheart rate variability030229 sport sciencesintervalliharjoitteluAutonomic nervous systemrunning performancePhysical EnduranceCardiologyPhysical therapybusinessVO2maxHigh-intensity interval trainingmedicine.drugInternational Journal of Sports Medicine
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Intraoperative imaging findings in transcranial MR imaging-guided focused ultrasound treatment at 1.5T may accurately detect typical lesional finding…

2020

To assess the intraoperative neuroimaging findings in patients treated with transcranial MR-guided focused ultrasound (tcMRgFUS) thalamotomy using 1.5T equipment in comparison with the 48-h follow-up.Fifty prospectively enrolled patients undergoing unilateral tcMRgFUS thalamotomy for either medication-refractory essential tremor (n = 39) or Parkinson tremor (n = 11) were included. Two radiologists evaluated the presence and size of concentric lesional zones (zone I, zone II, and zone III) on 2D T2-weighted sequences acquired intraoperatively after the last high-energy sonication and at 48 h. Sonication parameters including number of sonications, delivered energy, and treatment temperatures …

AdultMalemedicine.medical_specialtyessential tremor; high-intensity focused ultrasound ablation; interventional magnetic resonance imaging; Parkinson disease; stereotaxic techniqueshigh-intensity focused ultrasound ablationInterventional magnetic resonance imagingmedicine.medical_treatmentStereotaxic techniqueSonicationThalamusmedicineHumansRadiology Nuclear Medicine and imagingessential tremorNeuroradiologyAgedUltrasonographyAged 80 and overIntraoperative Caremedicine.diagnostic_testEssential tremorThalamotomybusiness.industryUltrasoundinterventional magnetic resonance imagingSettore MED/37 - NeuroradiologiaInterventional radiologyGeneral Medicinestereotaxic techniquesMiddle Agedmedicine.diseaseMagnetic Resonance ImagingParkinson diseaseCoagulative necrosisSurgery Computer-AssistedStereotaxic techniqueSettore MED/26 - NeurologiaFemaleRadiologySettore MED/36 - Diagnostica Per Immagini E Radioterapiabusiness
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Neuromuscular Adaptations to Short-Term High-Intensity Interval Training in Female Ice-Hockey Players

2019

Kinnunen, J-V, Piitulainen, H, and Piirainen, JM. Neuromuscular adaptations to short-term high-intensity interval training in female ice-hockey players. J Strength Cond Res 33(2): 479-485, 2019-High-intensity interval training (HIIT)-related neuromuscular adaptations, changes in force production, and on-ice performance were investigated in female ice-hockey players during preseason. Fourteen Finnish championship level ice-hockey players (average age 22 ± 3 years) participated in 2½-week HIIT. Both spinal (H-reflex) and supraspinal (V-wave) neuromuscular responses of the soleus muscle were recorded before and after the training period. Static jump (SJ) and countermovement jump heights, plant…

Adultelectromyographynaisetmedicine.medical_specialtyAdolescentAcceleration030209 endocrinology & metabolismPhysical Therapy Sports Therapy and RehabilitationElectromyographyAthletic PerformanceHigh-Intensity Interval Trainingta3112Interval trainingYoung Adult03 medical and health sciencesIce hockey0302 clinical medicinePhysical medicine and rehabilitationTibialis anterior musclemedicineHumansOrthopedics and Sports MedicineMuscle Skeletalta315Training periodco-activationSoleus musclemedicine.diagnostic_testbusiness.industry030229 sport sciencesGeneral MedicineAdaptation PhysiologicalCoactivationintermittent trainingelektromyografiaHockeyAthletesSkatingHoffmann ReflexPhysical therapyFemalewomenbusinesshuman activitiesHigh-intensity interval trainingJournal of Strength and Conditioning Research
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Changes in inflammation markers after a 10-week high-intensity combined strength and endurance training block in women: The effect of hormonal contra…

2019

Abstract Objectives The influence of hormonal contraceptives (HC) on inflammation and body composition after high-intensity combined strength and endurance training was investigated. Design Active healthy women formed two training groups: HC users (HCU, n = 9) and those who had never used HC (NHC, n = 9). Training included two strength training sessions and two high-intensity interval training sessions per week for 10 weeks. Methods Before (PRE) and after (POST) the training intervention, high-sensitivity C-reactive protein (hs-CRP), tumor necrosis factor alpha (TNF-α), interleukin-6 (IL-6), and interleukin-1beta (IL-1β) concentrations were measured. Dual-energy X-ray absorptiometry was use…

Adultmedicine.medical_specialtyAdolescentStrength trainingPhysical Therapy Sports Therapy and RehabilitationInflammationHigh-Intensity Interval TrainingInterval trainingFat massYoung Adult03 medical and health sciencesAbsorptiometry Photon0302 clinical medicineEndurance trainingInternal medicineContraceptive Agents FemalemedicineHumansOrthopedics and Sports Medicine030212 general & internal medicineInflammationInterleukin-6Tumor Necrosis Factor-alphabusiness.industryResistance Training030229 sport sciencesEndurance TrainingC-Reactive ProteinBody CompositionLean body massFemalemedicine.symptombusinessBiomarkersBiomedical sciencesHormoneJournal of Science and Medicine in Sport
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