Search results for "hiki"

showing 10 items of 37 documents

Determination of molecular mass, Stokes' radius, frictional coefficient and isomer-type of non-denatured proteins by time-dependent pore gradient gel…

1988

Molecular mass, Stoke's radius, frictional coefficient and isomer-type of non-denatured proteins can be obtained by time-dependent gradient gel electrophoresis by evaluating the resulting data using a two-step mathematical procedure. Provided a histochemical staining procedure is available to locate the position of an enzyme in the gel, crude cell extracts can be used for estimating their molecular size properties. The computation of molecular properties of non-denatured proteins is demonstrated for isozymes of aspartate aminotransferase (EC 2.6.1.1), peroxidase (EC 1.11.1.42) and glucose-6-phosphate dehydrogenase (EC 1.1.1.49) from current-year needles of spruce. The resulting data as well…

Gel electrophoresisShikimate dehydrogenaseChromatographyMolecular massChemistryGlutamate dehydrogenaseClinical BiochemistryReproducibility of ResultsDehydrogenaseEnvironmental pollutionStereoisomerismBiochemistryCatalysisAnalytical ChemistryEnzymesMolecular WeightCalibrationElectrophoresis Polyacrylamide GelPolyacrylamide gel electrophoresisStokes radiusPlant ProteinsElectrophoresis
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Populetum pamiricae ass. nova – an endemic forest association to Pamir in Tajikistan (Middle Asia)

2015

Abstract The floristic structure, distribution and habitat requirements of a forest syntaxon, Populetum pamiricae ass. nova is described. The potential range of the Populetum pamiricae association comprises the mountains of eastern Tajikistan (Pamir Alai Mts), Kashgaria in western China (Kunlun Shan Mts) and north-eastern Afghanistan (Hindu Kush Mts) in Middle Asia. The biotope of this community comprises of high mountain river valleys situated at elevations between 2,500 and 3,200 m above sea level. Phytocoenoses of the Populetum pamiricae association are characterized by the apparent domination in the tree layer of a diagnostic species, Populus pamirica. The tree stand has a mean cover ar…

General Immunology and MicrobiologyBetulo-Populetalia talassicaeGeneral NeuroscienceMiddle asiaalpine vegetationфлораBiologyGeneral Biochemistry Genetics and Molecular BiologyPopuletum pamiricaeПамир горыNova (rocket)Таджикистанlcsh:Biology (General)TadzhikistanEthnologysyntaxonomyсинтаксономияGeneral Agricultural and Biological Scienceslcsh:QH301-705.5Gornyi BadakhshanOpen Life Sciences
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A genome-wide view of Caenorhabditis elegans base-substitution mutation processes

2009

Knowledge of mutation processes is central to understanding virtually all evolutionary phenomena and the underlying nature of genetic disorders and cancers. However, the limitations of standard molecular mutation detection methods have historically precluded a genome-wide understanding of mutation rates and spectra in the nuclear genomes of multicellular organisms. We applied two high-throughput DNA sequencing technologies to identify and characterize hundreds of spontaneously arising base-substitution mutations in 10 Caenorhabditis elegans mutation-accumulation (MA)-line nuclear genomes. C. elegans mutation rate estimates were similar to previous calculations based on smaller numbers of m…

GeneticsGenome HelminthMutation rateMultidisciplinaryPoint mutationGenetic VariationHelminth geneticsSequence Analysis DNABiological SciencesDNA HelminthBiologyMutation AccumulationBackground selectionPolymorphism Single NucleotideGenomeGenètica molecularGenetic hitchhikingSpecies SpecificityMutation (genetic algorithm)AnimalsPoint MutationCaenorhabditis elegansGenome-Wide Association Study
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Herbicidal derivatives of aminomethylenebisphosphonic acid. Part III. Structure-activity relationship.

1997

Derivatives of aminomethylenebisphosphonic acids constitute a class of promising herbicides. More than 40 N-substituted aminomethylenephosphonic acids were synthesized and evaluated for their herbicidal activity on common cress (Lepidium sativum L.) and cucumber (Cucumis sativus L.). Some of the tested compounds were found to exhibit strong herbicidal properties being equal in activity with the popular herbicide glyphosate as well as parent N-pyridylaminomethylenephosphonic acids. N-Substituted iminodi(methylenephosphonic) acids, which may be considered as close analog of glyphosate, were inactive toward test plants.

GlyphosatebiologyShikimate pathwayPlant physiologyBiological activityPlant ScienceBisphosphonatesbiology.organism_classificationChemical synthesisLepidium sativumchemistry.chemical_compoundBiochemistrychemistryShikimate pathway; Glyphosate; BisphosphonatesGlyphosateShikimate pathwayOrganic chemistryStructure–activity relationshipAgronomy and Crop ScienceCucumis
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Protagonistu attiecību un identitātes atspoguļojums animē "Jauna gadsimta evaņģēlijs" (1995)

2021

Šī darba nosaukums ir “Protagonistu attiecību un identitātes atspoguļojums animē “Jauna gadsimta evaņģēlijs” (1995)”. Animē ir apspriestas tādas indivīdam svarīgas tēmas un jautājumi, kā sevis pieņemšana un nenoliegšana, nebēgšana no realitātes, spēja iekļauties sabiedrībā, nezaudējot savas indivīda vajadzības. Šajā darbā uzsvars ir likts uz tēlu emocijām, psiholoģisko problēmu rašanās iemesliem un sekām, kā arī individualitātes izpausmēm un to nozīmes. Darba ietveros tika tulkoti izvēlēti teksti no datu avota (animes), pētīti psiholoģiskie tipi un induviduālpsiholoģiskie kompleksi. Analizējot tēlu emocijas, runu, ķermeņa valodu, attiecību izmaiņas un to ietekmējošos cēloņus, tika secināts,…

InduviduālpsiholoģijaĀzijas studijasHikikomoriIndividualitāteAttiecībasKomunikācija
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Chemical constituents, total phenolic content, antioxidant activity and bactericidal effect of Dicliptera verticillate (Acanthaceae)

2021

Abstract This study investigated the phytochemical constituents and evaluated the total phenolic content, it also determined the antioxidant and antibacterial activities of the ethanol (EtOH) extract of the whole plant of Dicliptera verticillata. The phytochemical study was carried out using repeated silica gel column chromatography followed by Sephadex LH-20 to purify the extract which afforded three known compounds: lutein (1), shikimic acid (2) and guaiacylglycerol (3). The structures of these compounds were identified after analyses of their NMR and MS data and comparison of these data with those reported in the literature. The antioxidant and antibacterial activities were evaluated by …

LuteinAntioxidantbiologymedicine.medical_treatmentAcanthaceaePlant ScienceShikimic acidbiology.organism_classificationDiclipterachemistry.chemical_compoundColumn chromatographyPhytochemicalchemistrySephadexmedicineFood scienceSouth African Journal of Botany
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The Hikikomori Phenomenon of Social Withdrawal: An Emerging Condition Involving Youth's Mental Health and Social Participation.

2020

The objective of this editorial is to raise awareness on the burden and risks faced by adolescents developing this emerging form of social withdrawal. The hikikomori phenomenon is part of the group of new morbidities causing children and adolescents to limit their activity owing to a chronic health condition with attendant psychological problems. We further emphasize the importance of including new morbidities involving mental health and social participation in formal pediatric training, to enable new generations of pediatricians to identify and properly manage these disorders.

Malemedicine.medical_specialtySocial psychology (sociology)Adolescentmedia_common.quotation_subjectMEDLINEhikikomori phenomenonShameSocial epidemiologyShameGlobal HealthYoung AdultSettore MED/38 - Pediatria Generale E SpecialisticamedicineGlobal healthHumansPsychiatrymedia_commonbusiness.industryPhobia SocialSocial engagementmedicine.diseaseMental healthHikikomoriSocial IsolationPediatrics Perinatology and Child HealthFemalebusinessHikikomori Phenomenon Social Withdrawal Youth Mental HealthThe Journal of pediatrics
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Mode of action of herbicidal derivatives of aminomethylenebisphosphonic acid. I. Physiologic activity and inhibition of anthocyanin biosynthesis

1996

N-Pyridylaminomethylenebisphosphonic acids constitute a class of promising herbicides. Since their mode of action at the cellular level is still poorly understood, we studied the influence of N-pyridylaminomethylenebisphosphonic acids on plant growth, at the whole plant and undifferentiated tissue levels, using seedlings and cell suspension cultures of mono- and dicotyledonous species. These compounds exhibited strong herbicidal properties, being equipotent with the popular herbicide glyphosate. Since they also depressed buckweed anthocyanin biosynthesis, the shikimate pathway could represent a site of action of N-pyridylaminomethylenebisphosphonic acids.

N-Pyridylaminomethylenebisphosphonates; Anthocyanins; Herbicides; GlyphosateN-PyridylaminomethylenebisphosphonatesPlant physiologyPlant ScienceBiologyanthocyaninschemistry.chemical_compoundMetabolic pathwayherbicidesglyphosatechemistryMechanism of actionBiochemistryBiosynthesisAnthocyaninGlyphosatemedicineShikimate pathwaymedicine.symptomMode of actionAgronomy and Crop ScienceJournal of Plant Growth Regulation
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Intracellular compartmentation and regulation of two shikimate dehydrogenase isoenzymes in Pisum sativum

1974

Summary Pea seeds as well as sprouts and roots contain two isoenzymes of shikimate dehydrogenase. Both isoenzymes can be separated by Polyacrylamide gel electrophoresis as well as through ammonium sulfate fractionation. The molecular weight of both isoenzymes are the same although the net electric charge is different. The Km value for isoenzyme 1 is 3,5 × 10 −4 and the Km value for isoenzyme 2 is 1,67 × 10 −4 M. 3,4-dihydroxybenzoic acid, 3,5-dihydroxybenzoic acid, gallic acid, anthranilic acid and p-methoxycinnamic acid inhibited both isoenzymes competitively. Anthranlic acid showed the largest affinity to both isoenzymes. M-methoxycinnamic acid and m-nitrocinnamic acid inhibited both isoe…

Shikimate dehydrogenaseGeneral MedicineBiologybiology.organism_classificationMolecular biologyIsozymePisumchemistry.chemical_compoundCytosolchemistryBiochemistryAnthranilic acidMicrobodyGallic acidPolyacrylamide gel electrophoresisZeitschrift für Pflanzenphysiologie
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Media use during adolescence: the recommendations of the Italian Pediatric Society

2019

Abstract Background The use of media device, such as smartphone and tablet, is currently increasing, especially among the youngest. Adolescents spend more and more time with their smartphones consulting social media, mainly Facebook, Instagram and Twitter because. Adolescents often feel the necessity to use a media device as a means to construct a social identity and express themselves. For some children, smartphone ownership starts even sooner as young as 7 yrs, according to internet safety experts. Material and methods We analyzed the evidence on media use and its consequences in adolescence. Results In literature, smartphones and tablets use may negatively influences the psychophysical d…

Sleep Wake DisordersAdolescentEye DiseasesAddictionPoison controlCyberbullyingDevelopmental psychology03 medical and health sciences0302 clinical medicineDistractionInjury preventionHumansMedicineInterpersonal RelationsSocial mediaMusculoskeletal Diseases030212 general & internal medicineSocial identity theoryInternet safetyInternetLearning Disabilitiesbusiness.industryResearchCommunicationlcsh:RJ1-570Human factors and ergonomicslcsh:PediatricsAdolescent DevelopmentAwarenessmedicine.diseaseSettore MED/38AdolescenceBehavior AddictiveSocial IsolationHikikomoriComputers HandheldMedia deviceSmartphoneSedentary Behaviorbusiness030217 neurology & neurosurgeryItalian Journal of Pediatrics
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