Search results for "hip"

showing 10 items of 9327 documents

Effect of spontaneous activity at the old age on adult hippocampal neurogenesis in lrt and hrt rats

2018

Fyysinen aktiivisuus on hyväksi aivoterveydelle ja lisää aikuisiällä tapahtuvaa aivoturson eli hippokampuksen neurogeneesiä. Fyysisestä harjoittelusta saatavat vasteet riippuvat kuitenkin osittain geneettisistä tekijöistä ja siksi fyysisen harjoittelun vaikutukset ovat yksilöllisiä. Tämän tutkielman tarkoituksena on selvittää valikoivasti jalostettujen rottalinjojen spontaania fyysistä aktiivisuutta ja liikunnan vaikutuksia aivoterveydelle, kun fyysinen aktiivisuus on aloitettu myöhäisellä iällä pitkän inaktiivisuuden jälkeen. Tutkimuksessa käytettyjen rottien ikä vastaa noin 45 vuoden ihmisikää. Tutkimuksen rotat eroavat harjoitteluun reagoivuuden osalta ja omaavat joko korkean tai matalan…

neurogeneesihippokampusfyysinen aktiivisuus
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Voimaharjoittelun vaikutus uusien hermosolujen säilymiseen hippokampuksessa aikuisilla nisäkkäillä

2016

Aerobinen harjoittelu vaikuttaa positiivisesti hippokampuksen uusien hermosolujen syntymiseen ja selviytymiseen. Lisääntyneen neurogeneesin on tutkittu vaikuttavan aivojen rakenteisiin ja toimintaan, muun muassa tehostamalla muistin ja oppimisen toimintoja. Tässä tutkimuksessa käytetyllä voimaharjoittelulla on myös tutkittu olevan positiivinen vaikutus kognitiivisiin toimintoihin. Nyt tutkittiin aikuisilla nisäkkäillä suoritetun progressiivisen voimaharjoittelun vaikutuksia hippokampuksen pykäläpoimun uusien hermosolujen säilymiseen. Lisäksi tutkittiin onko voimaharjoittelulla vaikutusta paikkamuistiin. Tutkimuksen koe-eläiminä käytettiin sukukypsiä Sprague-Dawley rottia (n = 20), jotka jae…

neurogeneesioppiminenmuistivoimaharjoitteluhippokampusaerobinen harjoittelu
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The lizard cerebral cortex as a model to study neuronal regeneration

2002

The medial cerebral cortex of lizards, an area homologous to the hippocampal fascia dentata, shows delayed postnatal neurogenesis, i.e., cells in the medial cortex ependyma proliferate and give rise to immature neurons, which migrate to the cell layer. There, recruited neurons differentiate and give rise to zinc containing axons directed to the rest of cortical areas, thus resulting in a continuous growth of the medial cortex and its zinc-enriched axonal projection. This happens along the lizard life span, even in adult lizards, thus allowing one of their most important characteristics: neuronal regeneration. Experiments in our laboratory have shown that chemical lesion of the medial cortex…

neurogênese pós-natalMedial cortexhippocampushipocampoHippocampusBiologyHippocampal formationcélulas-troncomedicineAnimalsmedial cortexcortex mediallcsh:Scienceneural stem cellsCerebral CortexNeuronsMultidisciplinaryzincLizardsAnatomypostnatal neurogenesisNeural stem cellNerve Regenerationregeneraçãomedicine.anatomical_structurenervous systemzincoCerebral cortexregenerationModels AnimalFascia dentatalcsh:QNeuronSeasonsEpendymaNeuroscienceAnais da Academia Brasileira de Ciências
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Effect of combination therapy with hypothermia, magnesium and tirilazad in an experimental model of diffuse cerebral ischemia

2007

Objetivo. Valorar el grado de neuroprotección combinando hipotermia con magnesio y tirilazad en la isquemia cerebral global. La isquemia cerebral es uno de los problemas de mayor interés en la actualidad con unas medidas terapéuticas limitadas. La utilización de la hipotermia, una de las más eficaces, junto con los fármacos neuroprotectores puede ser una alternativa válida. Diseño. Estudio experimental con grupo control y dos niveles de aplicación de medidas terapéuticas. Ámbito. Laboratorio experimental de la Facultad de Medicina. Participantes y método. Veintiocho ratas Wistar sufrieron isquemia cerebral global de 10 minutos de duración mediante la combinación del clampaje carotídeo bilat…

neuroprotectorsbusiness.industryneuroprotectoresmagnesiumCritical Care and Intensive Care Medicinecerebral ischemianeuroprotecciónisquemia cerebralmagnesiotirilazadMedicineneuroprotectionbusinesshipotermiahypothermiaHumanities
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The role of the hippocampal theta activity in classical eyeblink conditioning in rabbits

2009

neuropsykologiaoppiminenExperimental PsychologymuistiHippocampusehdollistuminenNeuropsychologyMemoryEyeblink ReflexLearningkokeellinen psykologiahippokampusTheta RhythmConditioned Responses
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Mecanismos moleculares por los que la hiperamonemia crónica induce neuroinflamación y alteraciones en la neurotransmisión en cerebelo de ratas hipera…

2022

La encefalopatía hepática (EH) es un síndrome neuropsiquiátrico complejo que resulta de la insuficiencia hepática. La insuficiencia hepática induce hiperamonemia e inflamación periférica dando lugar a neuroinflamación con activación de microglía y astrocitos y aumento de los niveles de citocinas proinflamatorias. La neuroinflamación altera la neurotransmisión, lo que lleva a un deterioro cognitivo y motor. Las ratas con hiperamonemia crónica reproducen los déficits cognitivos y motores que presentan los pacientes con encefalopatía hepática mínima (EMH). Tanto en pacientes como en modelos animales, el cerebelo parece ser la primera área del cerebro afectada en las primeras etapas de MHE. El …

neurotransmisióncerebelohiperamonemiaUNESCO::CIENCIAS DE LA VIDAneuroinflamaciónneurona de purkinje:CIENCIAS DE LA VIDA [UNESCO]
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From state-owned smokestacks to post-industrial dreams : The Finnish government in business, 1970–2010

2020

While state-owned enterprises (SOEs) used to be considered obsolete tools for governmental intervention in the economy, in recent years governmental intervention in the business sector has re-emerged as a topic of debate. However, scholarship on the changes in and the modernisation of the SOE model is limited. In this article, we examine how the Finnish state’s ownership policy adapted to the requirements of economic globalisation between the 1970s and the 2010s. We show that the attitude towards globalisation was pragmatic and aimed at safeguarding the competitiveness of domestic companies. The state-owned company system was gradually adapted to meet new needs, losing most of its original …

new public managementHistoryomistuskilpailukyky060106 history of social sciencesState ownedyksityinen sektoritalouspolitiikkaownership policycorporate governancestate-owned enterpriseEconomic globalizationgovernment business relationsvaltionyhtiötMarket economyvarieties of capitalism0502 economics and businessvaltionohjausBusiness sector0601 history and archaeologyjulkinen omistusgovernmental intervention in the economyeconomic globalizationBusiness and International ManagementR&D policiesGovernmentCorporate governance05 social sciencesState capitalism06 humanities and the artsyrityksetIntervention (law)state capitalismNew public managementinnovation policiesBusiness Management and Accounting (miscellaneous)Businessjulkinen hallinto050203 business & management
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Pedagogical leadership to support new teachers' growth

2016

This study aims to discover the impact of pedagogical leadership on new teachers’ growth. The research is focused on three questions: 1) Are new teachers’ feelings and challenges being understood?; 2) How do new teachers receive support from principals and the school community?; and 3) How does pedagogical leadership impact new teachers’ growth? The research uses the qualitative approach of case studies. Four Finnish schools were selected as participants. The principals of each school and their five new teachers, with less than three years of experience, participated in the interviews. Teachers in Finland have common challenges when they first enter the profession. Finnish school communitie…

new teacherinservice teacher educationtukeminenammatillinen kehitysbasic educationpedagogical leadershipprofessional growthpedagoginen johtaminenFinnish teacheropettajatopettajankoulutusteacher induction
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Configural learning in rabbit nictitating membrane conditioning : acquisition of biconditional discrimination

2004

nictitating membrane conditioningprefrontal cortexehdollistuminenkaniinitkonfigurointioppiminenbiconditional discriminationhippocampusconfigural learningmultiunit activityrabbitvilkkuluomi
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Acidity and basicity of primaryN-phenylnitramines: catalytic effect of protons on the nitramine rearrangement

2002

Para-substituted N-phenylnitramines were prepared either by oxidation of diazonium salts or by nitration under alkaline or acidic conditions. Isotopic [15N-NO2] labelling indicated that the bands characteristic of the N-nitro group appear in the 1318–1323 and 1585–1607 cm−1 regions. In the nitrogen NMR spectra, the nitramino group gives two resonances at −193 ± 3 (NH) and −32 ± 3 ppm (NO2). The chemical shifts in proton and carbon NMR spectra are predictable, based on increments and the additivity rule. The spectral data indicate the lack of conjugation between the nitramino group and another substituent bound to the ring. It seems to contradict the well-known fact that substituents strongl…

nitraminesReaction mechanismChemical shiftrearrangementOrganic ChemistryInorganic chemistrySubstituentProtonationNuclear magnetic resonance spectroscopyCarbon-13 NMRMedicinal chemistryNMR spectra databasechemistry.chemical_compoundNMR spectroscopychemistryNitrationamphiprotic compoundsreaction mechanismPhysical and Theoretical ChemistryJournal of Physical Organic Chemistry
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