Search results for "hippokampus"
showing 4 items of 34 documents
CA3–CA1 long‐term potentiation occurs regardless of respiration and cardiac cycle phases in urethane‐anesthetized rats
2023
Breathing and heartbeat synchronize to each other and to brain function and affect cognition in humans. However, it is not clear how cardiorespiratory rhythms modulate such basic processes as synaptic plasticity thought to underlie learning. Thus, we studied if respiration and cardiac cycle phases at burst stimulation onset affect hippocampal long-term potentiation (LTP) in the CA3–CA1 synapse in urethane-anesthetized adult male Sprague–Dawley rats. In a between-subjects design, we timed burst stimulation of the ventral hippocampal commissure (vHC) to systole or diastole either during expiration or inspiration and recorded responses throughout the hippocampus with a linear probe. As classic…
Protein levels of brain-derived neurotrophic factor in the hippocampus of low/high aerobic capacity rats
2010
Hippocrates and Plato have first documented the connection between a healthy mind and body, during a period which launched analytical thinking and philosophy in Ancient Greece. Modern research has also indicated the contribution of an active lifestyle to enhanced brain performance and decreased incidence of neurodegenerative diseases and mood disorders such as Alzheimer’s disease and depression respectively. This has been hypothesized to emerge through mechanisms which are enhanced by exercise and contribute on brain plas-ticity and health. The Neurotrophins hypothesis implicates several molecules in brain plasticity and healthy aging. Among them, Brain-derived Neurotrophic Factor (BDNF) ha…
Aerobisen juoksuharjoittelun ja korkean intensiteetin intervalliharjoittelun vaikutukset hippokampuksen neurogeneesiin ja vaskularisaatioon rotilla
2014
TIIVISTELMÄ Petra Johansson (2014). Aerobisen juoksuharjoittelun ja korkean intensiteetin intervalliharjoittelun vaikutukset hippokampuksen neurogeneesiin ja vaskularisaatioon rotilla. Liikuntabiologian laitos, Jyväskylän yliopisto, Pro gradu -tutkielma, 55 s. Johdanto. Juoksuharjoittelun on todettu vaikuttavan myönteisesti oppimiseen, muistiin sekä aivojen toimintaan. Juoksuharjoittelu lisää hippokampuksen pykäläpoimun neurogeneesiä eri ikäryhmissä. Lisäksi juoksun on todettu vaikuttavan nuorilla pykäläpoimun vaskularisaatioon. Tarkoitus. Hippokampuksen neurogeneesiä ja vaskularisaatiota on tutkittu lähinnä vain aerobisella juoksuharjoittelulla. Tämän vuoksi tässä tutkimuksessa tutkittiin …
Rhythmic Memory Consolidation in the Hippocampus
2022
Functions of the brain and body are oscillatory in nature and organized according to a logarithmic scale. Brain oscillations and bodily functions such as respiration and heartbeat appear nested within each other and coupled together either based on phase or based on phase and amplitude. This facilitates communication in wide-spread neuronal networks and probably also between the body and the brain. It is a widely accepted view, that nested electrophysiological brain oscillations involving the neocortex, thalamus, and the hippocampus form the basis of memory consolidation. This applies especially to declarative memories, that is, memories of life events, for example. Here, we present our vie…