Search results for "hoito"

Associations of Sex Hormones and Hormonal Status With Arterial Stiffness in a Female Sample From Reproductive Years to Menopause

2021

Objective: Loss of sex hormones has been suggested to underlie menopause-associated increment in cardiovascular risk. We investigated associations of sex hormones with arterial stiffness in 19–58-years-old women. We also studied associations of specific hormonal stages, including natural menstrual cycle, cycle with combined oral contraceptives (COC) and menopausal status with or without hormone therapy (HT), with arterial stiffness. Methods: This study includes repeated measurements of 65 healthy women representing reproductive (n=16 natural, n=10 COC-users) and menopause (n=5 perimenopausal, n=26 postmenopausal, n=8 HT-users) stages. Arterial stiffness outcomes were aortic pulse wave veloc…

Africa's High Population Growth : Asking Tanzanian Women Why

2018

Community-dwelling older adults and their informal carers call for more attention to psychosocial needs - Interview study on unmet care needs in thre…

2022

Background: Unmet care needs are usually defined in terms of receiving sufficient help in instrumental activities and activities of daily living. Research on unmet needs is mostly based on quantitative data. Older persons’ and informal carers’ views and experiences have received less attention. Methods: In this paper, we rely on a definition of unmet needs which includes both unmet needs due to insufficient care and those situations where informal carers experience undue strain. Using theory-driven content analysis, we examine community-dwelling older adults’ and their informal carers’ experiences of unmet needs: what kind of unmet needs they have, why and in which ways these needs are left…

Power training and postmenopausal hormone therapy affect transcriptional control of specific co-regulated gene clusters in skeletal muscle

2010

At the moment, there is no clear molecular explanation for the steeper decline in muscle performance after menopause or the mechanisms of counteractive treatments. The goal of this genome-wide study was to identify the genes and gene clusters through which power training (PT) comprising jumping activities or estrogen containing hormone replacement therapy (HRT) may affect skeletal muscle properties after menopause. We used musculus vastus lateralis samples from early stage postmenopausal (50–57 years old) women participating in a yearlong randomized double-blind placebo-controlled trial with PT and HRT interventions. Using microarray platform with over 24,000 probes, we identified 665 diffe…

Muscular transcriptome in postmenopausal women with or without hormone replacement.

2007

The loss of muscle mass and strength with aging is well characterized, but our knowledge of the molecular mechanisms underlying the development of sarcopenia remains incomplete. Although menopause is often accompanied with first signs of age-associated changes in muscle structure and function, the effects of hormone replacement therapy (HRT) or menopause-related decline in estrogen production in the muscles of postmenopausal women is not well understood. Furthermore the knowledge of the global transcriptional changes that take place in skeletal muscle in relation to estrogen status has thus far been completely lacking. We used a randomized double-blinded study design together with an explor…

Asthma, allergies and respiratory symptoms in different activity groups of swimmers exercising in swimming halls

2021

Abstract Background Respiratory symptoms are common in competitive swimmers. However, among these and in swimmers at other activity levels the swimming distance, the total spent time in swimming halls and their medical background varies. Our objectives were, first, to assess their medical histories and the associations with respiratory symptoms among swimmers in different activity groups and then second, to study the pulmonary function findings and related medications in competitive swimmers who exercise in swimming hall environments the most. Methods First, 1118 participants consisting of 133 competitive-, 734 fitness- and 251 occasional swimmers answered questionnaires concerning their me…

"Sitä vaan hengitetään, joskus yksin ja joskus yhdessä" : tapaustutkimus sosiaalisen fobian tuomista haasteista terapeuttisen yhteistyösuhteen muodos…

2014

Tämän pro gradu -tutkielman tarkoituksena on selvittää sosiaalisen fobian vaikutusta terapeuttisen yhteistyösuhteen rakentumiseen yhden kokonaisen terapiaprosessin aikana. Lisäksi tutkimuksen tarkoituksena on kuvata asiakkaan ja terapeutin kokemia yhteistyösuhteeseen liittyviä haasteita sekä tarkastella niitä Bordinin (1979) yhteistyösuhteen teorian valossa. Aineistomme koostuu yhdestä Jyväskylän yliopiston opetus- ja tutkimusklinikalle sosiaalisen fobian vuoksi hakeutuneen asiakkaan koko 54 istuntoa kattavasta terapiaprosessista. Tutkielma on luonteeltaan laadullinen tapaustutkimus, jonka analyysimenetelmänä käytämme tapaustutkimusten ja pienten aineistojen tutkimiseen kehitettyä tulkitsev…

Reporting, Reflecting and Recognising Emotions in Therapeutic Work with Domestic Violence Perpetrators : Experiences of the Jyväskylä Group Model

2020

Emotions are central in therapeutic work, but interventions for violence vary in how they address emotions. While emotional work with perpetrators is often associated with ‘anger management’ and behavioural elements, a more comprehensive view of emotions might be beneficial in efforts to stop and prevent violent behaviour. Perpetrators’ self-regulation can be promoted by recognising and addressing primary feelings (vulnerability, fear, jealousy, etc.) that may manifest as anger and aggressive behaviour. However, this kind of therapeutic work with perpetrators of violence is also challenging for professionals. For example, when working towards ending violence, it is crucial to differentiate …

Biologinen sosiaalisen mallina. Valintoja uuden hedelmöityshoitolain kentällä.

2007

Tarkastelen artikkelissa hedelmöityshoitoja koskevan lakiprosessin aikaista kamppailua, joka realisoitui Laiksi hedelmöityshoidoista (1237/2006). Analysoin tarkemmin lain viidettä pykälää (1237/2006, 5§) sekä siitä lakiesityksessä HE 3/2006 esitettyjä perusteluja. Pykälän mukaan lääkärin tulee valita sukusolujen luovuttajista hoitoa saavan parin osapuolia muistuttavat henkilöt, sillä lapsen tulee saada muistuttaa myös sosiaalista vanhempaansa. Analysoin lain viidennen pykälän sisältämiä vanhempien ja lapsen asemaa koskevia lausumia modaalisuusanalyyttisesti käyttäen apuna semioottista neliötä. Neliön kautta ilmennän hoitoihin osallistuvien positioiden modaalista astevaihtelua, joka osoittaa…

Predicting hospital associated disability from imbalanced data using supervised learning.

2019

Hospitalization of elderly patients can lead to serious adverse effects on their functional capability. Identifying the underlying factors leading to such adverse effects is an active area of medical research. The purpose of the current paper is to show the potential of artificial intelligence in the form of machine learning to complement the existing medical research. This is accomplished by studying the outcome of hospitalization of elderly patients as a supervised learning task. A rich set of features characterizing the medical and social situation of elderly patients is leveraged and using confusion matrices, association rule mining, and two different classes of supervised learning algo…