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SPA centru tēls to tīmekļa vietnēs: žanra un multimodālā analīze
2018
Lai klients būtu ieinteresēts turpmākā saziņā ar uzņēmumu, ir svarīgi radīt neaizmirstamu pirmo iespaidu, kas ir viena no mājaslapas funkcijām. Šī pētījuma mērķis bija raksturot sešas SPA centru mājaslapas. Lai sasniegtu šī pētījuma mērķi, tika izvēlēta uz korpusu balstīta pieeja, kas ietvēra Beitmena (Bateman) (2008) izstrādāto žanra un multimodālo (GeM) modeli un Suena (Suen) (2009) piecu soļu modeli, kas tika izmantots mājaslapas izkārtojuma un retoriskās struktūras analīzei. Turklāt Kresa un van Lēuvena (Kress and van Leeuwen) (2006) sociālās semiotikas modelis tika izmantots, lai veiktu attēlu analīzi, kas noteiktu kā vizuālās reprezentācijas metafunkcija palīdz veidot SPA centra tēlu …
Macrophages as an Emerging Source of Wnt Ligands: Relevance in Mucosal Integrity
2019
The Wnt signaling pathway is a conserved pathway involved in important cellular processes such as the control of embryonic development, cellular polarity, cellular migration, and cell proliferation. In addition to playing a central role during embryogenesis, this pathway is also an essential part of adult homeostasis. Indeed, it controls the proliferation of epithelial cells in different organs such as intestine, lung, and kidney, and guarantees the maintenance of the mucosa in physiological conditions. The origin of this molecular pathway is the binding between Wnt ligands (belonging to a family of 19 different homologous secreted glycoproteins) and their specific membrane receptors, from …
Alzheimer's disease: new diagnostic and therapeutic tools.
2008
Abstract On March 19, 2008 a Symposium on Pathophysiology of Ageing and Age-Related diseases was held in Palermo, Italy. Here, the lectures of M. Racchi on History and future perspectives of Alzheimer Biomarkers and of G. Scapagnini on Cellular Stress Response and Brain Ageing are summarized. Alzheimer's disease (AD) is a heterogeneous and progressive neurodegenerative disease, which in Western society mainly accounts for clinica dementia. AD prevention is an important goal of ongoing research. Two objectives must be accomplished to make prevention feasible: i) individuals at high risk of AD need to be identified before the earliest symptoms become evident, by which time extensive neurodege…
Neural Stem Cells in the Adult Brain: From Benchside to Clinic
2012
Increasing evidence indicates that neural stem cells (NSCs) play an important role in sustaining cellular homeostasis and brain tissue restoration. The study of all mechanisms that control and modulate the function of NSC is a crucial step for the design of therapies against chronic neurodegenerative processes. In this special issue of the journal, we had the pleasure to edit the topic entitled “Neural Stem Cells in the Adult Brain: From Benchside to Clinic.” This special compilation of paper was aimed to provide a global forum for publications of original peer-reviewed manuscripts that reported original research findings in the field of adult neural stem cell, including short communication…
Relationship Between Oxidative Stress, ER Stress, and Inflammation in Type 2 Diabetes: The Battle Continues
2019
Type 2 diabetes (T2D) is a metabolic disorder characterized by hyperglycemia and insulin resistance in which oxidative stress is thought to be a primary cause. Considering that mitochondria are the main source of ROS, we have set out to provide a general overview on how oxidative stress is generated and related to T2D. Enhanced generation of reactive oxygen species (ROS) and oxidative stress occurs in mitochondria as a consequence of an overload of glucose and oxidative phosphorylation. Endoplasmic reticulum (ER) stress plays an important role in oxidative stress, as it is also a source of ROS. The tight interconnection between both organelles through mitochondrial-associated membranes (MAM…
Phenotypic Buffering in a Monogenean: Canalization and Developmental Stability in Shape and Size of the Haptoral Anchors of Ligophorus cephali (Monog…
2015
Phenotypic variation results from the balance between sources of variation and counteracting regulatory mechanisms. Canalization and developmental stability are two such mechanisms, acting at two different levels of regulation. The issue of whether or not they act concurrently as a common developmental buffering capacity has been subject to debate. We used geometric morphometrics to quantify the mechanisms that guarantee phenotypic constancy in the haptoral anchors of Ligophorus cephali. Canalization and developmental stability were appraised by estimating inter- and intra-individual variation, respectively, in size and shape of dorsal and ventral anchors. The latter variation was estimated…
Validation of the Dutch eating behavior questionnaire for children (DEBQ-C) for use with Spanish children Validación del cuestionario holandés de com…
2011
Introduction: The Dutch Eating Behaviour Questionnaire for children was developed by Van Strien and Oosterveld (2008) to measure three different eating behaviors (emotional eating, restrained eating and external eating); it is an adaptation of the DEBQ for adults. Objective: The purpose of this study is to analyze the psychometric properties of the Dutch Eating Behavior Questionnaire for Children (DEBQ-C) with a Spanish sample. Method: The DEBQ-C was administered to 473 children (240 boys and 233 girls), from 10 to 14 years old. The sample included a Clinical Overweight Group (COG; n = 81) comprising children who were receiving weight loss treatments, a Non Clinical Overweight Group (NCOG, …
Finnish Adolescent Girls’ Activity Patterns and The Effects of an Activity-Based Homework Intervention on Their Physical Activity
2021
Purpose: The insufficient physical activity (PA) of adolescents is a global challenge, and there is a need to find opportunities to engage youth in active lifestyles. The majority of adolescents do not meet the recommended guidelines of physical activity, and especially females have low levels of activity as they approach adolescence. The goal of this study was to obtain insight into Finnish adolescent girls’ objectively measured physical activity by evaluating the effects of an activity-based homework intervention on low, medium, and high-active girls during after-school hours. Method: A physical activity homework intervention was put into place for female adolescent girls. Physical activi…
Nurses' Experiences of Caring for Older Persons in Transition to Receive Homecare: Being Somewhere in between Competing Values
2013
Older persons in transition to need professional care in their homes will constitute a large group in municipalities in the future. The aim of this study was to obtain insight into nurses' experiences and perceptions of caring for patients in transition to receive homecare. Eleven home nurses divided into two focus groups were interviewed, and a phenomenological hermeneutical design was used. Four interpretations closely related to each other were revealed: it is essential to have an understanding of the patients' transition history; the nurse' repertoire is challenged in the transition process; care must be adapted to the patients' life world; the excellence of care is threatened by the co…
Dannelse og samskaping av utdanning mellom akademia og sykehjem
2020
Cultivation and co-creation of education between academy and nursing home - a critical ethnography study Collaboration between academy and practice in education is emphasized. In this study, we explored and described boundary-crossing spaces, when co-creating an adjusted educational program for nursing students in a nursing home in Norway. Our aim was to explore how to learn person-centered dementia care through the participants in a learning community. A critical ethnographic approach and method with observations, field n otes, minutes of board, spontaneous meetings, and focus groups particularly with the students were used. Data were analyzed with six-step thematic analysis by Braun and…