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Reliability of adapted version of Italian Label tobacco Impact Index for the adolescent: ALII
2017
OBJECTIVE: The aim of this study is to assess the reliability of the Adolescent Label Impact Index (ALII) , it is an adolescent adapted version of Italian LII of the tobacco products warnings. MATERIAL AND METHODS: A sample including students aged 13-15 years was considered. The ALII is constructed by 4 items: salience, harm, quitting and forgo. The questionnaire was self-administered to study participants twice with 3 days between each administration (T1 and T2) to measure reliability. The internal consistency using Cronbach's alpha and Corrected Item-Total Correlations (CITC) and the test-retest reliability applying Pearson's correlation were computed. RESULTS: Cronbach's alpha ranges fro…
Adapting and validating scale of customer engagement in online travel communities
2020
Increasing attention towards customer engagement has caused its measurement to remain a highly debated issue among scholars. This study adapts and validates measurement scales for customer engagement in Online Travel Communities. It builds on previous studies on scale development for customer engagement. Data were collected from 450 members of Online Travel Communities in eight countries: Australia, Canada, Hong Kong (Chinese territory), New Zealand, Singapore, South Africa, the United Kingdom and the United States of America. The process of adapting and validating the scale involved exploratory factor analysis, testing for differential item functioning, examination of item response theory,…
Análisis de la cultura organizacional de la Facultad de Psicología de la Universidad de Valencia
2017
Resumen Este artículo analiza la cultura organizativa de la Facultad de Psicología de la Universidad de Valencia (España). Se ha utilizado el Inventario de Cultura Organizacional de Cooke y Lafferty, validado por la literatura científica y muy empleado. Mide tres estilos culturales: constructivo, pasivo-defensivo y agresivo-defensivo. El instrumento se ha aplicado a una muestra de 363 alumnos/as del grado de Psicología, obteniéndose bajos niveles en el índice de desviación media, lo que permite establecer conclusiones a nivel agregado. En suma, la cultura percibida en este centro universitario no sobresale especialmente por ningún estilo en particular, aunque apunta muy ligeramente hacia un…
Unmet care needs are common among community-dwelling older people with memory problems in Finland
2021
Aims: Ageing in place has become a policy priority. Consequently, residential care has been reduced, and more older people with multiple care needs reside at home with the help of informal care and home care services. An increasing share of these people has memory disorders. We examined the extent to which memory problems, in addition to other individual characteristics, are associated with unmet care needs among community-dwelling older people. Methods: The study employed cross-sectional survey data from community-dwelling people aged 75+ collected in 2010 and 2015, analysed using binary logistic regression analysis. The study population consisted of people who had long-term illnesses or d…
Myrkylliset aikuiset
2021
Uzņēmumu mājas lapu žanra analīze
2017
Sākumlapai ir nozīmīga loma pievilcīgā veidā prezentēt mājaslapas satura izvilkumu. Šī pētījuma mērķis bija veikt struktūras analīzi multinacionālo uzņēmumu korporatīvām sākumlapām. Balstoties uz Korporatīvas Mājaslapas Modeļa pamatu (Askehave un Nielsen, 2005), tika veikta kvalitatīvā un kvantitatīvā izpēte trīsdesmit nejauši izvēlētām uzņēmumu korporatīvām sākumlapām. Teorētiskais pētījums atklāja, ka uzņēmumu sākumlapas satur noteiktus retoriskos soļus un hipersaites ar noteiktu tipu, kuras var analizēt piemērojot žanra analīzi. Secinājumi empīriskajā pētījumā atklāja, ka gandrīz visas izvēlētās sākumlapas lieto CHP modeli…
Are paradoxical intensity-dependent effects of 5Hz rTMS train in motor cortex of migraine with aura patients evidence of abnormal homeostatic plastic…
2010
Aplidin® induces JNK-dependent apoptosis in human breast cancer cells via alteration of glutathione homeostasis, Rac1 GTPase activation, and MKP-1 ph…
2006
Aplidin® is an antitumor agent in phase II clinical trials that induces apoptosis through the sustained activation of Jun N-terminal kinase (JNK). We report that Aplidin® alters glutathione homeostasis increasing the ratio of oxidized to reduced forms (GSSG/GSH). Aplidin® generates reactive oxygen species and disrupts the mitochondrial membrane potential. Exogenous GSH inhibits these effects and also JNK activation and cell death. We found two mechanisms by which Aplidin® activates JNK: rapid activation of Rac1 small GTPase and downregulation of MKP-1 phosphatase. Rac1 activation was diminished by GSH and enhanced by L-buthionine (SR)-sulfoximine, which inhibits GSH synthesis. Downregulatio…
Home literacy environment and inside-out emergent literacy skills of children with differing familial risk of dyslexia
2001
Regulación espacio-temporal de la homeostasis del cobre en Arabidopsis thaliana
2013
El cobre y el hierro son nutrientes esenciales para los seres vivos aerobios y sus potenciales redox son utilizados en las reacciones de transferencia de electrones. Sin embargo, esta capacidad redox resulta tóxica cuando los metales de transición entran en contacto con intermediarios del metabolismo aerobio, conocidos como ROS (reactive oxygen species). Los organismos aerobios han desarrollado estrategias homeostáticas para mantener los niveles de los metales adecuados en la célula y distribuir, espacial y temporalmente, los procesos de transporte y tráfico intracelular de metales para minimizar el daño oxidativo al resto de procesos celulares. En este sentido, recientemente se ha demostra…