Search results for "hospital mortality"

showing 10 items of 196 documents

Short-term and long-term results of cardiac surgery in elderly and very elderly patients

2011

Objective: Cardiac operations in elderly patients are increasingly frequent and imply major clinical, ethical, and economic issues. Operative and 5-year results of cardiac operations in patients aged 79 years or more are known in limited series, and a debate is ongoing on the appropriateness of selection of patients for surgery. Methods: We retrospectively reviewed our experience in 6802 patients aged 79 years or more who had received a cardiac operation. Surgical candidates were selected according to functional status, crude operative risk, and social context and were managed according to a multimodality protocol. Results: Mean age was 82 years and surgery was nonelective in 1613 cases (23…

MaleTime Factorsmedicine.medical_treatmentKaplan-Meier Estimatelaw.inventionAMIValve replacementlawRetrospective StudieRisk FactorsThoracic aortaCardiac Surgical ProcedureDuke Activity Status IndexAge FactorMyocardial infarctionHospital MortalityCABGAged 80 and overAge FactorsCanadian Cardiovascular Societycardiopulmonary bypaCardiac surgery"Gruppo Villa Maria"Survival RateGVMTreatment OutcomeItalyElective Surgical Procedurescardiovascular systemCardiologyFemaleCardiology and Cardiovascular MedicineHumanPulmonary and Respiratory Medicinemedicine.medical_specialtyLogistic ModelTime Factoracute myocardial infarctionRisk Assessmentcoronary artery bypass graftInternal medicinemedicine.arteryNew York Heart AssociationmedicineCardiopulmonary bypassHumansCardiac Surgical ProceduresSurvival rateAgedProportional Hazards ModelsRetrospective StudiesElective Surgical Procedurebusiness.industryRisk FactorPatient SelectionCPBRetrospective cohort studyCanadian Cardiovascular SocietySettore MED/23 - Chirurgia Cardiacamedicine.diseaseDASICCSSurgeryLogistic ModelsProportional Hazards ModelSurgeryNYHAbusinessThe Journal of Thoracic and Cardiovascular Surgery
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Results of mitral valve repair for Barlow disease (bileaflet prolapse) via right minithoracotomy versus conventional median sternotomy: a randomized …

2011

Objective: The results of mitral repair for complex Barlow valves are adequate and support earlier intervention. It is unknown whether these results are reproducible in the context of minimally invasive surgery via right minithoracotomy. Methods: We randomized patients with Barlow mitral disease (bileaflet prolapse) to have conventional open repair via median sternotomy (MS group) or minimally invasive (MI group) repair. Repair was done using polytetrafluoroethylene chordal reimplantation for both leaflets. In the MI group, we adopted right minithoracotomy, peripheral cannulation, external aortic clamping, and surgery under direct vision. Results: Both groups comprised 70 patients. The oper…

MaleTime Factorsmedicine.medical_treatmentKaplan-Meier Estimatelaw.inventionlawRisk FactorsMitral valveCardiac Surgical ProcedureHospital MortalityProspective StudiesUltrasonographyPain PostoperativeMitral Valve ProlapseAtrial fibrillationGenetic Diseases X-LinkedMiddle Agedmedicine.anatomical_structureTreatment OutcomeItalyThoracotomyCardiologyMitral ValveFemaleCardiology and Cardiovascular MedicineHumanPulmonary and Respiratory MedicineAdultReoperationmedicine.medical_specialtyTime FactorContext (language use)Risk AssessmentInternal medicineCardiopulmonary bypassmedicineHumansCardiac Surgical ProceduresMechanical ventilationMitral valve repairMitral regurgitationChi-Square Distributionbusiness.industryRisk FactorPatient SelectionSettore MED/23 - Chirurgia Cardiacamedicine.diseaseSternotomySurgeryProspective StudieMedian sternotomySurgerybusinessThe Journal of thoracic and cardiovascular surgery
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Penn classification in acute aortic dissection patients

2016

Objective The objective of this study was to evaluate the effectiveness of the Penn classification in predicting in-hospital mortality after surgery in acute type A aortic dissection patients. Methods We evaluated 58 patients (42 men and 16 women; mean age 62.17 ± 10.6 years) who underwent emergency surgery for acute type A aortic dissection between September 2003 and June 2010 in our department. We investigated the correlation between the pre-operative malperfusion and in-hospital outcome after surgery. Results Twenty-eight patients (48%) were Penn class Aa (absence of branch vessel malperfusion or circulatory collapse), 11 (19%) were Penn class Ab (branch vessel malperfusion with ischaemi…

MaleType A dissection Stanford classification DeBakey classification Penn classificationMyocardial IschemiaRisk AssessmentOutcome Assessment (Health Care)Outcome Assessment Health CarePreoperative CareStanford classificationHumansSettore MED/05 - Patologia ClinicaHospital MortalityAgedType A dissection – Stanford classification – DeBakey classification – Penn classificationPenn classificationSettore MED/23 - Chirurgia CardiacaShockGeneral MedicineMiddle AgedPrognosisAneurysmDeBakey classification; Penn classification; Stanford classification; Type A dissection; Aged; Female; Hospital Mortality; Humans; Italy; Male; Middle Aged; Myocardial Ischemia; Outcome Assessment (Health Care); Preoperative Care; Prognosis; Risk Assessment; Shock; Vascular Surgical Procedures; Aneurysm Dissecting; Aortic AneurysmAortic AneurysmSettore MED/23Aortic DissectionItalyDeBakey classificationType A dissectionFemaleCardiology and Cardiovascular MedicineVascular Surgical ProceduresDissecting
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Predicting in-hospital mortality from Coronavirus Disease 2019: A simple validated app for clinical use

2021

Backgrounds Validated tools for predicting individual in-hospital mortality of COVID-19 are lacking. We aimed to develop and to validate a simple clinical prediction rule for early identification of in-hospital mortality of patients with COVID-19. Methods and findings We enrolled 2191 consecutive hospitalized patients with COVID-19 from three Italian dedicated units (derivation cohort: 1810 consecutive patients from Bergamo and Pavia units; validation cohort: 381 consecutive patients from Rome unit). The outcome was in-hospital mortality. Fine and Gray competing risks multivariate model (with discharge as a competing event) was used to develop a prediction rule for in-hospital mortality. D…

MaleViral DiseasesEpidemiologyClinical prediction ruleCardiovascular MedicineVascular MedicineSteroid TherapyChronic Liver DiseaseCohort StudiesMedical ConditionsEndocrinologyRetrospective StudieRisk FactorsMedicine and Health Sciences80 and overCoronary Heart DiseaseHospital MortalityAged 80 and overMultidisciplinaryPharmaceuticsLiver DiseasesQHazard ratioRMiddle AgedMobile ApplicationsHospitalsHospitalizationInfectious DiseasesBrier scoreItalyCardiovascular DiseasesMedicineFemaleHumanResearch ArticleCohort studyAdultmedicine.medical_specialtyEndocrine DisordersCorticosteroid TherapyScienceSettore MED/12 - GASTROENTEROLOGIAMobile ApplicationCardiologyGastroenterology and HepatologyRisk AssessmentDrug TherapyInternal medicineDiabetes MellitusmedicineHumansAgedRetrospective StudiesReceiver operating characteristicbusiness.industrySARS-CoV-2Risk FactorSettore MED/09 - MEDICINA INTERNACOVID-19Covid 19Retrospective cohort studyCardiovascular Disease RiskTriageConfidence intervalHealth CareROC CurveHealth Care FacilitiesMedical Risk FactorsMetabolic DisordersCohort Studiebusiness
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A New Prognosis Score to Predict Mortality After Acute Pneumonia in Very Elderly Patients

2016

International audience; Objectives: Acute pneumonia (AP) induces an excess of mortality among the elderly. We evaluated the value of a new predictive biomarker index compared to usual prognosis scores for predicting in-hospital and 1-year mortalities in elderly inpatients with AP.Design: Retrospective study in 6 clinical departments of a university hospital.Setting: Burgundy university hospital (France).Participants: All patients aged 75 and over with AP and hospitalized between January 1 and June 30, 2013, in the departments of medicine (5) and intensive care (1) of our university hospital.Measurements: A new index, which we named UBMo, was created by multiplying the uremia (U in the formu…

Malecommunity-acquired pneumoniaPneumonia severity indexseveritysepsis0302 clinical medicineElderlyadultsscoreHospital Mortality030212 general & internal medicineProspective cohort studyGeneral NursingAged 80 and overvalidation[SDV.MHEP.GEG]Life Sciences [q-bio]/Human health and pathology/Geriatry and gerontologyHealth PolicyMortality rateGeneral Medicinecohort3. Good healthAcute DiseaseFemaleFranceterm survivalmanagementmedicine.medical_specialtyhospitalized-patients[ SDV.MHEP.GEG ] Life Sciences [q-bio]/Human health and pathology/Geriatry and gerontology03 medical and health sciencesPredictive Value of TestsIntensive careInternal medicinemedicineHumanspneumoniaIntensive care medicineAgedRetrospective Studiesbusiness.industrybiomarkersRetrospective cohort studymedicine.diseasemortalityUremiaPneumoniaBlood pressure030228 respiratory systemprognosisGeriatrics and Gerontologybusiness
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Prognostic Impact of Hyponatremia and Hypernatremia in COVID-19 Pneumonia. A HOPE-COVID-19 (Health Outcome Predictive Evaluation for COVID-19) Regist…

2020

Dysnatremia is associated with increased mortality in patients with community-acquired pneumonia. SARS-COV2 (Severe-acute-respiratory syndrome caused by Coronavirus-type 2) pneumonia can be fatal. The aim of this study was to ascertain whether admittance dysnatremia is associated with mortality, sepsis, or intensive therapy (IT) in patients hospitalized with SARS-COV2 pneumonia. This is a retrospective study of the HOPE-COVID-19 registry, with data collected from January 1th through April 31th, 2020. We selected all hospitalized adult patients with RT-PCR-confirmed SARS-COV2 pneumonia and a registered admission serum sodium level (SNa). Patients were classified as hyponatremic (SNa <…

MalehyponatremiaEndocrinology Diabetes and Metabolism030204 cardiovascular system & hematologyGlobal Healthlcsh:Diseases of the endocrine glands. Clinical endocrinology:Health Care::Health Care Quality Access and Evaluation::Quality of Health Care::Health Care Evaluation Mechanisms::Outcome and Process Assessment (Health Care) [Medical Subject Headings]:Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings]sepsis0302 clinical medicineEndocrinology:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Cohort Studies::Retrospective Studies [Medical Subject Headings]HiponatremiaOutcome Assessment Health CareSARS-COV2Hospital MortalityRegistriesOriginal Research:Persons::Persons::Age Groups::Adult::Aged [Medical Subject Headings]:Health Care::Environment and Public Health::Public Health::Epidemiologic Methods::Data Collection::Registries [Medical Subject Headings]HypernatremiahypernatremiaMiddle AgedPrognosisVirusHospitalizationSurvival Rate:Analytical Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Patient Care::Hospitalization [Medical Subject Headings]HipernatremiaFemaleHyponatremiaHyponatremiamedicine.medical_specialty:Information Science::Information Science::Data Collection::Vital Statistics::Mortality::Survival Rate [Medical Subject Headings]Coronavirus disease 2019 (COVID-19)Infecciones por coronavirus:Check Tags::Male [Medical Subject Headings]030209 endocrinology & metabolismSepsis03 medical and health sciencesInternal medicineSepsis:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Cohort Studies::Longitudinal Studies::Follow-Up Studies [Medical Subject Headings]medicineHumans:Diseases::Nutritional and Metabolic Diseases::Metabolic Diseases::Water-Electrolyte Imbalance::Hypernatremia [Medical Subject Headings]MortalitySurvival rateAgedRetrospective Studieslcsh:RC648-665business.industrySARS-CoV-2COVID-19Retrospective cohort study:Persons::Persons::Age Groups::Adult::Middle Aged [Medical Subject Headings]Aparato respiratoriomedicine.diseasemortality:Diseases::Virus Diseases::RNA Virus Infections::Nidovirales Infections::Coronaviridae Infections::Coronavirus Infections [Medical Subject Headings]Clinical trialbody regionsPneumonia:Check Tags::Female [Medical Subject Headings]:Diseases::Nutritional and Metabolic Diseases::Metabolic Diseases::Water-Electrolyte Imbalance::Hyponatremia [Medical Subject Headings]Mortalidad:Analytical Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Prognosis [Medical Subject Headings]:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Data Collection::Vital Statistics::Mortality::Hospital Mortality [Medical Subject Headings]HypernatremiabusinessFollow-Up Studies
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Impact of atrial fibrillation/flutter on the in-hospital mortality of surgical patients – Results from the German nationwide cohort

2020

To investigate the impact of atrial fibrillation/flutter (AF) on adverse in-hospital outcomes in hospitalized surgical patients.The nationwide German inpatient sample of the years 2005-2018 was used for this analysis. Surgical patients were stratified by AF and compared. Logistic regression models were used to investigate the impact of AF on in-hospital outcomes.In total, 96,589,627 hospitalizations with surgery were included in the present analysis in Germany (2005-2018). Among these, 6,680,261 were additionally coded with AF (6.9%). In-hospital death rate was substantially higher in surgical patients with AF (6.3%) than without (1.1%). Proportion of surgical patients with AF increased fro…

Malemedicine.medical_specialty030204 cardiovascular system & hematologyLogistic regression03 medical and health sciences0302 clinical medicineRisk FactorsGermanyInternal medicineAtrial FibrillationmedicineHumansHospital MortalityRisk factorHeart FailureAtrial fibrillation flutterIn hospital mortalitybusiness.industryMortality rateAtrial fibrillationHematologymedicine.diseaseAtrial Flutter030220 oncology & carcinogenesisCohortFemalebusinessSurgical patientsThrombosis Research
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Impact of atrial fibrillation/flutter on the in-hospital mortality of ischemic stroke patients.

2020

Stroke is the second leading cause of death worldwide. Ischemic strokes, which are caused by atrial fibrillation/flutter (AF), may be more devastating than those that occur without AF.The purpose of this study was to investigate the impact of AF on adverse events in hospitalized ischemic stroke patients and to estimate the elevated impact of AF on the occurrence of these adverse events.The nationwide German inpatient sample of the years 2005-2015 was used for this analysis. Ischemic stroke patients were identified by ICD code I63 and stratified by AF. Logistic regression models were used to investigate the impact of AF on adverse in-hospital events and adjusted for age, sex, and comorbiditi…

Malemedicine.medical_specialty030204 cardiovascular system & hematologyLogistic regressionBrain Ischemia03 medical and health sciences0302 clinical medicineRisk FactorsPhysiology (medical)Internal medicineCause of DeathGermanyCase fatality rateAtrial FibrillationmedicineHumanscardiovascular diseases030212 general & internal medicineHospital MortalityAdverse effectStrokeCause of deathAgedRetrospective StudiesAged 80 and overInpatientsAtrial fibrillation flutterbusiness.industryAtrial fibrillationMiddle Agedmedicine.diseasePrognosisSurvival RateAtrial FlutterIschemic strokeCardiologyFemaleCardiology and Cardiovascular MedicinebusinessHeart rhythm
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Use of hydroxychloroquine in hospitalised COVID-19 patients is associated with reduced mortality: Findings from the observational multicentre Italian…

2020

Abstract Background Hydroxychloroquine (HCQ) was proposed as potential treatment for COVID-19. Objective We set-up a multicenter Italian collaboration to investigate the relationship between HCQ therapy and COVID-19 in-hospital mortality. Methods In a retrospective observational study, 3,451 unselected patients hospitalized in 33 clinical centers in Italy, from February 19, 2020 to May 23, 2020, with laboratory-confirmed SARS-CoV-2 infection, were analyzed. The primary end-point in a time-to event analysis was in-hospital death, comparing patients who received HCQ with patients who did not. We used multivariable Cox proportional-hazards regression models with inverse probability for treatme…

Malemedicine.medical_specialty030204 cardiovascular system & hematologyLower risklaw.inventionCOVID-19; Disease severity; Hydroxychloroquine; Inflammation; Mortality; Aged; Aged 80 and over; COVID-19; Female; Hospital Mortality; Humans; Hydroxychloroquine; Italy; Male; Middle Aged; Retrospective Studies; Treatment OutcomeCOVID-19; Disease severity; Hydroxychloroquine; Inflammation; Mortality03 medical and health sciences0302 clinical medicineRandomized controlled trialRetrospective StudielawInternal medicine80 and overInternal MedicinemedicineHumans030212 general & internal medicineHospital MortalityMortalityRisk factorDisease severityAgedRetrospective StudiesInflammationAged 80 and overbusiness.industryMortality rateCOVID-19HydroxychloroquineRetrospective cohort studyMiddle AgedCOVID-19 Drug TreatmentTreatment OutcomeItalyPropensity score matchingCommentaryObservational studyFemalebusinessHumanmedicine.drugHydroxychloroquineEuropean journal of internal medicine
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Impact of atrial fibrillation on in-hospital mortality of ischemic stroke patients and identification of promoting factors of atrial thrombi – Result…

2019

Abstract Ischemic stroke is one of the leading causes of death and disability. Atrial fibrillation (AF) is a well-recognized risk factor for ischemic stroke. We aimed to investigate the impact of AF on in-hospital mortality of ischemic stroke patients and to identify parameters associated with intra-cardiac thrombogenic material. Patients were selected by screening the nationwide sample for ischemic stroke by ICD-Code (I63), stratified for AF. In this cohort, the association between in-hospital deaths and AF was investigated. In a second study, we performed a retrospective analysis of patients who underwent transesophageal echocardiography (TEE) for various reasons, assigned these to 2 grou…

Malemedicine.medical_specialty3400left atrial appendageObservational StudyComorbidity03 medical and health sciences0302 clinical medicineInternal medicineGermanyAtrial FibrillationmedicineechocardiographyHumans030212 general & internal medicineHospital MortalityRisk factorThrombusAgedRetrospective StudiesAged 80 and overbusiness.industryIncidence (epidemiology)Mortality rateAge FactorsRetrospective cohort studyAtrial fibrillationThrombosisGeneral MedicineMiddle Agedmedicine.diseaseComorbiditymortalitystroke3. Good health030220 oncology & carcinogenesisintracardiac thrombogenic materialCohortCardiologyFemalebusinessEchocardiography TransesophagealResearch ArticleMedicine
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