Search results for "hplc"

showing 10 items of 201 documents

Presiones antropogénicas en el Parque Natural de L’Albufera: Contaminación debida a fármacos y productos para el cuidado personal

2021

La contaminación medio ambiental, debida a la actividad antrópica, ha crecido de forma exponencial en el último siglo. Por esta razón la tesis se ha centrado en una clase de contaminantes, fiel reflejo de esta presión, los fármacos y productos para el cuidado personal (PPCPs). El trabajo realizado incluye la optimización de métodos analíticos para detectar estos compuestos y la aplicación de estos a muestras medioambientales, para evaluar el estado de contaminación de una importante Reserva Natural. En primer lugar, se realizó una revisión bibliográfica que describe la importancia de cada paso en la preparación de la muestra para optimizar la determinación de estos contaminantes en ecosiste…

contaminación ambiebtalHPLC-MS/MSUNESCO::QUÍMICAUNESCO::CIENCIAS DE LA VIDAParque Natural de L’Albuferafármacos:QUÍMICA [UNESCO]:CIENCIAS DE LA VIDA [UNESCO]productos para el cuidado personal
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Contaminants of emerging concern in the environment. Turia River as study case

2018

Tesis llevada a cabo para conseguir el grado de Doctor por la Universidad de Valencia.--2018-04-05

drogas de abusoQuEChERScontaminantes emergentesmétodo analíticotriple quadrupolo:QUÍMICA::Química analítica::Análisis cromatográfico [UNESCO]Tampón de McIlvaineMS/MSProductos de cuidado personalUNESCO::QUÍMICA::Química analítica::Análisis cromatográficoUNESCO::CIENCIAS DE LA TIERRA Y DEL ESPACIO::Hidrología ::Aguas superficialesHPLCQToFfármacos:CIENCIAS DE LA TIERRA Y DEL ESPACIO::Hidrología ::Aguas superficiales [UNESCO]Extracción en fase sólida
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Universal method to determine acidic licit and illicit drugs and personal care products in water by liquid chromatography quadrupole time-of-flight

2016

Graphical abstract

emerging contaminantsPersonal careChromatographyChemistrywater010401 analytical chemistryClinical Biochemistry010501 environmental sciencesMass spectrometryHigh resolution mass spectrometry01 natural sciencesquantificationNon-target screening by SPE and UHPLC quadrupole time-of-flight0104 chemical sciencesMedical Laboratory TechnologyLiquid chromatography–mass spectrometryEnvironmental ScienceUHPLCidentificationQuadrupole time of flightComputingMethodologies_COMPUTERGRAPHICS0105 earth and related environmental sciencesMethodsX
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Stereoselective Synthesis and Pharmacological Evaluation of 2,4-Bridged Piperidine Derivatives Designed to Activate the κ-Opioid Receptor

2021

endo-configurationdiastereoselective reductive aminationenantiomeric excessstructure-affinity relationshipNOESY spectrumKOR agonistconformational restrictionchiral HPLCSettore CHIM/08 - Chimica Farmaceutica2-azabicyclo[3.3.1]octanecis/trans configuration
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Chemical characterization of Anthemis parlatoreana fresh and dried aerial parts by GC and LC chromatographic techniques and evaluation of the antioxi…

2022

Anthemis parlatoreana was collected in the north west coast of Sicily. Fresh and dried aerial parts were subjected to distillation procedure for the extraction and isolation of essential oils. In both fresh and dried samples, the most abundant chemical classes were ketones and esters, represented to a greater extent by β-thujone and β-artemisia acetate, respectively. In dried vegetable material, a high content of α-pinene and δ3-carene was also registered. Aqueous, methanol and ethyl acetate extracts of aerial parts were also investigated in terms of polyphenolic content and antioxidant potential. All the extracts tested showed a quite different quali-quantitative profile and in terms of ch…

essential oil distillationGC-MS/FIDAnthemis parlatoreanaSettore BIO/02 - Botanica SistematicaHPLC-PDA/MSPlant ScienceSettore BIO/15 - Biologia FarmaceuticaEcology Evolution Behavior and Systematicspolyphenolsterpenes
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Acute responses of comprehensive gonadosteroids and corticosteroids to resistance exercise before and after 10 weeks of supervised strength training

2020

Resistance training is a potent stimulus for muscle growth and steroid hormones are known to play a role in this adaptation. However, very little is known about the acute exercise‐induced gonadosteroid and corticosteroid hormone responses, including key smaller‐concentration intermediate hormones. The present study determined the acute responses of these steroid hormone families using quantitative UHPLC mass spectrometry (MS) following resistance exercise in strength‐trained men. Venous and fingertip blood was drawn pre‐, mid‐, 5 min post‐ and 15 min post‐resistance exercise, both before and after 10 weeks of supervised resistance training. The experimental resistance exercise sessions cons…

estrogeenitmassaspektrometriahormonescortisolhormonitUHPLC mass spectroscopy11‐deoxycortisolandrostenedionetestosteroneestrogenmass spectroscopytestosteronisteroiditvoimaharjoitteluDHEAresistance traininghormonaaliset vaikutukset
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Estudio de los valores de referencia para los parámetros de estrés oxidativo: malondialdehído y glutatión, medidos por cromatografía líquida de alta …

2015

La investigación en estrés oxidativo ha experimentado una expansión masiva en los últimos años. Multitud de datos indican que la producción de especies reactivas en los sistemas biológicos regulan numerosos procesos fisiológicos. La producción descontrolada de estas especies está implicada en el inicio y propagación de diversas patologías. Una aproximación común para la determinación del estrés oxidativo en los sistemas biológicos consiste en la medida del aumento o el descenso de moléculas redox-sensibles que responden a este tipo de estrés. Los biomarcadores de estrés oxidativo usualmente se clasifican en 4 categorías. La primera engloba la detección de oxidantes. Desafortunadamente, la m…

estrés oxidativoUNESCO::CIENCIAS MÉDICASglutatiónradicales libresperoxidación lipídica en membranasHPLCmalondialdehído:CIENCIAS MÉDICAS [UNESCO]cromatografía líquida de alta eficacia
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Identification of Abies sibirica L. Polyprenols and Characterisation of Polyprenol-Containing Liposomes

2020

The needles of conifer trees are one of the richest sources of natural polyprenols. Polyprenol homologs from Abies sibirica L. lipophilic 80% purified extract were analyzed and quantified. In total, 10 peaks (Prenol-11 to Prenol-20) were observed in the ultra-high-performance liquid chromatography&ndash

food.ingredientPharmaceutical ScienceEthanol Injectionphysicochemical properties<i>Abies sibirica</i> L.High-performance liquid chromatographyLecithinAnalytical Chemistrylcsh:QD241-44103 medical and health sciencesPolyprenolchemistry.chemical_compound0302 clinical medicinefoodlcsh:Organic chemistryDrug DiscoverypolyprenolsPhysical and Theoretical ChemistrySolubility030304 developmental biology0303 health sciencesLiposomeChromatographybiologyOrganic ChemistryAbies sibiricabiology.organism_classificationchemistryChemistry (miscellaneous)030220 oncology & carcinogenesisYield (chemistry)liposomeMolecular MedicineHPLCMolecules
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The effect of the pore structure and zeta potential of porous polymer monoliths on separation performance in ion-exchange mode.

2007

Most often, in bioseparations involving charged macromolecules, the chromatographic systems have low Reynolds and high Peclet numbers. For such systems, an expression is developed and presented in this work for evaluating the throughput in polymeric monoliths where ion-exchange adsorption occurs, as a function of (i) the pressure drop along the length of the monolith, (ii) the functional form and width of the throughpore-size distribution of the monolith, and (iii) the magnitude of the zeta potential on the surface of the throughpores of the monolith. Gaussian and log-normal throughpore-size distributions whose mean throughpore-size and standard deviation values are based on experimentally …

geographygeography.geographical_feature_categoryMonolithic HPLC columnIon exchangeChemistryPolymersIon chromatographyAnalytical chemistryFiltration and SeparationPorosimetryCharged particleAnalytical ChemistryIon ExchangePhase (matter)Zeta potentialMonolithJournal of separation science
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Chiral gamma-lactones from Fusarium poae: enentiomeric ratios and sensory differentiation of cis-6-gamma-dodecenolactone enantiomers

1991

Chiral gamma-lactones from Fusarium poae: enentiomeric ratios and sensory differentiation of cis-6-gamma-dodecenolactone enantiomers

hplc chromatographycomposé volatilisomèrespectrométrie rmngas chromatographyisolémentchromatographie en phase gazeusemolecular structurenmr spectrometryarômechromatographie hplcstructure moléculaire[SDV.AEN] Life Sciences [q-bio]/Food and Nutritionisomerlactonetimeouthyphomycetes[SDV.AEN]Life Sciences [q-bio]/Food and Nutritionfusarium
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