Search results for "humana"
showing 10 items of 301 documents
Prenatal exposure to residential air pollution and infant mental development: modulation by antioxidants and detoxification factors.
2011
Background: Air pollution effects on children’s neurodevelopment have recently been suggested to occur most likely through the oxidative stress pathway. Objective: We aimed to assess whether prenatal exposure to residential air pollution is associated with impaired infant mental development, and whether antioxidant/detoxification factors modulate this association. Methods: In the Spanish INfancia y Medio Ambiente (INMA; Environment and Childhood) Project, 2,644 pregnant women were recruited during their first trimester. Nitrogen dioxide (NO2) and benzene were measured with passive samplers covering the study areas. Land use regression models were developed for each pollutant to predict aver…
Skin temperature in youth soccer players with functional equinus and non-equinus condition after running.
2018
Objectives To check how a thermal IR camera can check skin temperature in gastrocnemius‐soleus equinus condition and non‐gastrocnemius‐soleus condition in youth soccer players and thus detect association between the extensibility of the triceps surae (with gastrocnemius‐soleus equinus and non‐gastrocnemius‐soleus equinus) and the muscle temperature pattern. Design A cross‐sectional study secondary level of care. Methods Sample from an elite soccer academy in Madrid (Spain) 35 healthy male subjects (youth soccer players) age 12.82 ± 1.07 years, height 158.68 ± 10.79 cm, weight 49.19 ± 9.45 kg, body mass index 19.41 ± 2.25. The exclusion criteria were the presence of musculoskeletal and joint…
Effectiveness, safety/tolerability of OBV/PTV/r ± DSV in patients with HCV genotype 1 or 4 with/without HIV-1 co-infection, chronic kidney disease (C…
2019
Background and aims Limited data are available on the effectiveness and tolerability of direct-acting antivirals (DAAs) therapies in the real world for HCV-infected patients with comorbidities. This study aimed to describe the effectiveness of OBV/PTV/r +/- DSV (3D/2D regimen) with or without ribavirin (RBV) in HCV or HCV/HIV co-infected patients with GT1/GT4 and CKD (IIIb-V stages), including those under hemodialysis and peritoneal dialysis in routine clinical practice in Spain in 2015. Material and methods Non-interventional, retrospective, multicenter data collection study in 31 Spanish sites. Socio-demographic, clinical variables, study treatment characteristics, effectiveness and toler…
Does Function Determine the Structure? Changes in Flexor Hallucis Longus Muscle and the Associated Performance Related to Dance Modality: A Cross-Sec…
2020
Background and Objectives: Flexor hallucis longus pathology is one of the most common conditions of the ankle and foot in dancers, due to the high demand of dance movements performed in an extreme plantar flexion and dorsiflexion range of motion. The objectives of this study were to determine the bilateral differences between the thickness and cross-sectional area of the flexor hallucis longus muscle in dancers, to establish possible differences between dance modalities, and to analyze whether there is a correlation between ultrasonographic parameters or performance variables and the dance modality. Material and Methods: A sample of 50 (29 classical and 21 contemporary) full-time pre-profes…
In glacial environments beyond glacial terrains: Human eco-dynamics in late Pleistocene Mediterranean Iberia
2013
The Iberian Peninsula south of the Ebro River enjoyed one of the mildest climates of Pleistocene Europe, but still experienced significant and rapid environmental shifts caused by global climate regimes. We examine the interplay between technological, social, and land-use dynamics as culturally mediated responses to climate change outside the periglacial zone. We combine information from excavated sites across eastern and southeastern Spain with systematic survey data from an intensive study area within this larger region to examine Upper Paleolithic behavioral adaptations to the environmental shifts of the late Pleistocene (late MIS-3 through MIS-2). We define indexes that serve as proxies…
Activación del metabolismo energético del ratón mediante el tratamiento con resveratrol o genisteína.
2018
En los últimos años son muchos los estudios que se han realizado para evaluar las propiedades de los compuestos naturales en ciertas patologías, y como alguna de sus moléculas son capaces de modificar parámetros metabólicos en estados fisiopatológicos, causados por una enfermedad como la diabetes, obesidad e incuso cáncer, que tiene un gran componente metabólico. Es por ello que estudiar el efecto de los polifenoles, resveratrol o genisteína, puede ser de gran interés para comprender el mecanismo de acción mediante el cual inducen variaciones en el metabolismo. Son diversos los autores que han descrito que el resveratrol afecta el metabolismo energético y sirve como un mimético de restricci…
Movilidad humana: una revisión teórica aplicable de los flujos migratorios en España
2020
El texto tiene el objetivo de realizar una revisión teórica aplicable entorno a las migraciones en el contexto particular español. Se ha realizado una revisión bibliográfica aplicable disponible en torno al tema, con el fin de ofrecer una recopilación y selección de la información disponible a este respecto partiendo de la dicotomía que haría en su momento López de Lera (1995), los que “vienen a descansar y los que vienen a trabajar”. Es importante porque el desarrollo teórico de sendas perspectivas de la migración es divergente. Este es el aporte del texto, realizar un recorrido por los dos caminos migratorios y delimitar las principales corrientes.
Astrocytes Protect Neurons from Aβ1-42 Peptide-Induced Neurotoxicity Increasing TFAM and PGC-1 and Decreasing PPAR-γ and SIRT-1
2015
One of the earliest neuropathological events in Alzheimer's disease is accumulation of astrocytes at sites of Aβ1-42 depositions. Our results indicate that Aβ1-42 toxic peptide increases lipid peroxidation, apoptosis and cell death in neurons but not in astrocytes in primary culture. Aβ1-42-induced deleterious neuronal effects are not present when neurons and astrocytes are mixed cultured. Stimulation of astrocytes with toxic Aβ1-42 peptide increased p-65 and decreased IκB resulting in inflammatory process. In astrocytes Aβ1-42 decreases protein expressions of sirtuin 1 (SIRT-1) and peroxisome proliferator-activated receptor γ (PPAR-γ) and over-expresses peroxisome proliferator-activated re…
Transformaciones sociales y territoriales en el incremento de la movilidad por razón de trabajo en Andalucía
2007
Entre 1991 y 2001, tal como se deduce de la información de los censos de población de ambos años, se ha producido un importante incremento de la movilidad en Andalucía por razón de trabajo, especialmente de los desplazamientos entre municipios cercanos. Este trabajo indaga sobre los factores relacionados como causas, y también como consecuencias, con tal incremento. En primer lugar, los cambios en la estructura sectorial, ocupacional y socioeconómica de la población ocupada. En segundo lugar, la ampliación espacial de los mercados locales de trabajo. Y, en tercer lugar, la evolución de la organización espacial de la movilidad, especialmente de la movilidad metropolitana. La conclusión es qu…
Implicaciones del turismo masivo en un destino de cruceros
2020
[EN] One of the types of tourism that can generate greater problems of overtourism is cruise ship tourism, given the large number of people who disembark at a port of call to visit the destination. For this reason, the present study aims to analyze the perception of massification among cruise ship tourists visiting an important Mediterranean port of call and how it influences their satisfaction with their visit. To this end, using structural equation models and from a sample of cruise ship passengers, the model proposed in this study is tested. The results indicate that of the two typologies of massification analysed, it is spatial massification that contributes most to the perception of to…