Search results for "hydrodynamic"
showing 10 items of 530 documents
Liquid metal free surface dynamics in rotating permanent magnet stirrer
2020
Abstract We study liquid metal stirring by rotating permanent magnets in a laboratory-scale rectangular glass container. The main goal is numerical model validation using experimental free surface shape data. We find reasonable agreement between the experiments and coupled liquid metal magnetohydrodynamics simulations. Since the surface tension forces are not dominant here, free surface is deformed mainly by the dynamic pressure of the bulk flow. Therefore, we can conclude that not only the free surface profile is similar to experiments, but the bulk flow must be also very similar.
Computer simulations to approach surface tension by means of a simple mesoscopic mechanical model
2019
A small insect can stand or walk on water surface, drops of mercury do not spread on a solid surface, and a meniscus is formed at the free surface of a liquid contained in a thin vessel. These phenomena can be seen as macroscopic manifestations of molecular interactions and can be explained macroscopically in terms of surface tension. In this study, we deal with an approach to surface tension from a mechanical point of view, presenting a simple mesoscopic mechanical model of surface tension and the results of its implementation in numerical fluid dynamics simulations. Particularly, phenomena like droplet formation without gravity and with gravity when it can drop from a narrow hole like a t…
A practical methodology to perform global sensitivity analysis for 2D hydrodynamic computationally intensive simulations
2021
Sensitivity analysis is a commonly used technique in hydrological modeling for different purposes, including identifying the influential parameters and ranking them. This paper proposes a simplified sensitivity analysis approach by applying the Taguchi design and the ANOVA technique to 2D hydrodynamic flood simulations, which are computationally intensive. This approach offers an effective and practical way to rank the influencing parameters, quantify the contribution of each parameter to the variability of the outputs, and investigate the possible interaction between the input parameters. A number of 2D flood simulations have been carried out using the proposed combinations by Taguchi (L27…
Persistent episomal transgene expression in liver following delivery of a scaffold/matrix attachment region containing non-viral vector
2008
An ideal gene therapy vector should enable persistent transgene expression without limitations of safety and reproducibility. Here we report the development of a non-viral episomal plasmid DNA (pDNA) vector that appears to fulfil these criteria. This pDNA vector combines a scaffold/matrix attachment region (S/MAR) with a human liver-specific promoter (alpha1-antitrypsin (AAT)) in such a way that long-term expression is enabled in murine liver following hydrodynamic injection. Long-term expression is demonstrated by monitoring the longitudinal luciferase expression profile for up to 6 months by means of in situ bioluminescent imaging. All relevant control pDNA constructs expressing luciferas…
Development of S/MAR minicircles for enhanced and persistent transgene expression in the mouse liver.
2010
We have previously described the development of a scaffold/matrix attachment region (S/MAR) episomal vector system for in vivo application and demonstrated its utility to sustain transgene expression in the mouse liver for at least 6 months following a single administration. Subsequently, we observed that transgene expression is sustained for the lifetime of the animal. The level of expression, however, does drop appreciably over time. We hypothesised that by eliminating the bacterial components in our vectors, we could improve their performance since bacterial sequences have been shown to be responsible for the immunotoxicity of the vector and the silencing of its expression when applied i…
Dynamics of sediments along with their core properties in the Monastir-Bekalta coastline (Tunisia, Central Mediterranean)
2017
International audience; The authors report on two campaigns of high-resolution samplings along the shores of Monastir Bay in Tunisia: the first being a study of sediment dynamics, grain size and mineral composition in surface sediment, and the second, eight months later, using four sediment cores to study grain-size distribution in bottom sediments. Particle size analysis of superficial sediment shows that the sand in shallow depths is characterized by S-shaped curves, indicating a certain degree of agitation, possible transport by rip currents near the bottom and hyperbolic curves illustrating heterogeneity of sand stock. The sediments settle in a relatively calm environment. Along the bay…
A computational framework for coating fatigue analysis of wind turbine blades due to rain erosion
2021
Author's accepted manuscript The rain-induced fatigue damage in the wind turbine blade coating has attracted increasing attention owing to significant repair and maintenance costs. The present paper develops an improved computational framework for analyzing the wind turbine blade coating fatigue induced by rain erosion. The paper first presents an extended stochastic rain field simulation model that considers different raindrop shapes (spherical, flat, and spindle), raindrop sizes, impact angles, and impact speeds. The influence of these raindrop characteristics on the impact stress of the blade coating is investigated by a smoothed particle hydrodynamics approach. To address the expensive …
Simulation of the Propagation of Tsunamis in Coastal Regions by a Two-Dimensional Non-Hydrostatic Shallow Water Solver
2017
Due to the enormous damages and losses of human lives in the inundated regions, the simulation of the propagation of tsunamis in coastal areas has received an increasing interest of the researchers. We present a 2D depth-integrated, non- hydrostatic shallow waters solver to simulate the propagation of tsunamis, solitary waves and surges in coastal regions. We write the governing continuity and momentum equations in conservative form and discretize the domain with unstructured triangular Generalized Delaunay meshes. We apply a fractional- time-step procedure, where two problems (steps) are consecutively solved. In the first and in the second step, we hypothesize a hydrostatic and a non-hydro…
Autecology, lifestyle and hydrodynamics of early vertebrates
2018
Capítulo 1. Introducción general Los vertebrados constituyen uno de los grupos de animales más exitosos, contando con más de 60000 especies distintas y ocupando la gran mayoría de ecosistemas marinos y continentales. Su origen y evolución han sido temas centrales para biólogos y paleontólogos durante décadas, pero las discusiones en este sentido se han visto obstaculizadas porque los grupos actuales (ciclóstomos, condrictios y osteíctios) constituyen solo una pequeña representación de toda la diversidad que existió en el pasado. Por lo tanto, el registro fósil es crucial para arrojar luz sobre estos aspectos permitiendo desvelar el momento y el tempo de la aparición de los diferentes caract…
Experimental observation of the rule of flexible vegetation on erosion processes
2012
Vegetation altering hydrodynamic conditions of an open channel flow controls the exchanges of sediment, nutrients and contaminants. Thus, the knowledge of the hydraulic characteristics of flow over vegetation is very important to support the management of fluvial processes. But, the analysis of the hydrodynamic conditions is complex because vegetation is flexible in varying degrees and it oscillates in the flow changing position. Furthermore, because of temporal changing of roughness due to natural vegetative growth, the response of vegetation to the flow can change in time. Many theoretical and experimental investigations have been performed in order to analyze both the mean flow and turbu…