Search results for "iGen"
showing 10 items of 13400 documents
Model organisms and their application in environmental epigenetics
2020
Abstract Epigenetic mechanisms operate at the interface between the environment and the genome of a given organism. More particularly, they convert environmental stimuli as diverse as chemical pollutants, nutritional components, temperature changes, and social conditions into changes in the chromatin landscape, which influence gene expression in the absence of alterations in the DNA sequence, ultimately leading to phenotype adaptation and diversification. The use of experimental model organisms in epigenetics research allows for the careful manipulation of environmental factors in order to understand how they mechanistically modulate the establishment, maintenance, and inheritance of epigen…
When more is less: The other side of artificial intelligence recommendation
2022
Based on consumers' preferences, AI (artificial intelligence) recommendation automatically filters information, which provokes scholars' debate. Supporters believe that by analyzing the consumers' preferences, AI recommendation enables consumers to choose products more quickly and with lower cost. Critics deem that consumers are more easily trapped in information cocoons because of the use of AI recommendation. This reduces the possibility of consumers contacting with a variety of commodities, thus lowering the consumer decision quality. Based on experiments, this paper discusses the moderating role of AI recommendation on the relationship of consumers' preferences and information cocoons. …
Using AI to personalise emotionally appealing advertisement
2019
Personal data and information collected online by companies can be used to design and personalise advisements. This chapter extends existing research into the online behavioural advertising by proposing a model that incorporates artificial intelligence and machine learning into developing emotionally appealing advertisements. It is proposed that big data and consumer analytics collected through AI from different sources will be aggregated to have a better understanding of consumers as individuals. Personalised emotionally appealing advertisements will be created with this information and shared digitally using pragmatic advertising strategies. Theoretically, this chapter contributes towards…
« Deirdre O’Mahony, artiste et archéologue des savoirs techniques indigènes »
2022
Les projets participatifs et collaboratifs de l’artiste irlandaise Deirdre O’Mahony, ancrés dans le monde rural du Burren, valorisent le patrimoine vernaculaire et les savoir-faire indigènes. Ses recherches de terrain portant sur l’évolution du paysage abordé comme milieu et les collaborations multiples qu’elle entreprend aboutissent à des propositions artistiques revisitant le land art. Ses interventions dans le paysage sont souvent complétées par des propositions dialogiques, dont le repas partagé, qui invite les participants à explorer l’histoire des lieux, les jeux de pouvoir qui s’y tissent et la pertinence des savoirs vernaculaires pour les enjeux de demain, notamment en matière de sé…
L'araldica dei vescovi agrigentini dal Medioevo ai nostri giorni
2010
Desarrollo de una metodología de implantación de sistemas de vigilancia tecnológica e inteligencia competitiva en la gestión de organizaciones hotele…
2023
El propósito de esta tesis doctoral es conocer si la vigilancia tecnológica y la inteligencia competitiva es un recurso y/o una capacidad clave para la dirección estratégica en las organizaciones hoteleras, así como desarrollar un sistema normalizado de vigilancia tecnológica e inteligencia competitiva que permita incorporar un instrumento práctico de vigilancia de mercados, que mejore la toma de decisiones en la dirección estratégica de los establecimientos hoteleros. Este nuevo instrumento normalizado se diseña incorporando elementos de fuentes externas e internas, variables de vigilancia de mercados, clientes, destinos y productos aportando tres bloques de indicadores ponderados al aplic…
Propuesta Educativa para la Prevención de la Violencia de Género
2016
Promover la igualdad de género y los derechos de las mujeres ha sido una recomendación a todos los gobiernos, desde las primeras publicaciones al respecto, por parte de los distintos organismos internacionales. Hace 20 años que la OMS acordó que la violencia contra la mujer es un problema de Salud Pública y en todos los países del mundo se han llevado a cabo acciones intentando visibilizarla. En Septiembre de 2015 se aprobó la Agenda 2030 para el Desarrollo Sostenible (ODS), un paso más a partir de los Objetivos de Desarrollo del Milenio (2000). A pesar de no ser jurídicamente vinculantes, suponen un reto que marcan la dirección de las decisiones políticas a fin de alcanzar los 17 objetivos…
Justicia con perspectiva de género: análisis cuantitativo de estereotipos y revisión de la imparcialidad judicial en procesos por violencia sexual
2022
El objeto de estudio de esta tesis doctoral es la existencia de estereotipos de género en procesos por violencia sexual. A partir de la aplicación de la perspectiva de género y la realización de estudios empíricos se proponen una serie de mecanismos tendentes a proteger el derecho a la tutela judicial efectiva, especialmente la imparcialidad del juez, y garantizar el principio de debida diligencia del Estado. El cuestionamiento del androcentrismo jurídico por parte de la teoría crítica feminista pone de manifiesto la invisibilización, llegando incluso al olvido, de las mujeres como sujetos político-jurídicos y reconceptualiza el derecho como subjetivo, parcial e irracional si en su desarrol…
Pathogenic mechanisms of how human parvovirus breaks self-tolerance
2017
It is known that viral infections can cause acute, chronic, and autoimmune diseases (ADs). However, the mechanism of how a persistent viral infection contributes to ADs remains still unclear. In this thesis, pathological and immunological aspects of how common viruses can initiate autoimmunity were investigated, and human parvovirus B19 (B19V) was employed as a model virus. B19V non-structural protein 1 (NS1), a superfamily 3 (SF3) helicase, initiated DNA damage resulting in cellular apoptosis. The apoptotic bodies (ApoBods) induced by B19V NS1 were purified and characterized. These ApoBods contained viral NS1 proteins with modified autoimmune-associated self-antigens, e.g. DNA, Smith, Apol…
IgA-Dominant Infection-Associated Glomerulonephritis Following SARS-CoV-2 Infection
2021
The renal involvement of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been reported. The etiology of kidney injury appears to be tubular, mainly due to the expression of angiotensin-converting enzyme 2, the key joint receptor for SARS-CoV-2; however, cases with glomerular implication have also been documented. The multifactorial origin of this renal involvement could include virus-mediated injury, cytokine storm, angiotensin II pathway activation, complement dysregulation, hyper-coagulation, and microangiopathy. We present the renal histological findings from a patient who developed acute kidney injury and de novo nephrotic syndrome, highly suggestive of acute IgA-domina…