Search results for "iNOS"

Effect of LIF-withdrawal on acetylcholine synthesis in the embryonic stem cell line CGR8 is not mediated by STAT3, PI3Ks or cAMP/PKA pathways.

2015

Acetylcholine (ACh) acts as a local cellular signaling molecule and is widely expressed in nature, including mammalian cells and embryonic stem cells. The murine embryonic stem cell line CGR8 synthesizes and releases substantial amounts of ACh. Particularly during early differentiation - a period associated with multiple alterations in geno-/phenotype functions - synthesis and release of ACh are increased by 10-fold. In murine stem cells second messengers of the STAT-3, PI3K and cAMP/PKA pathways are involved in maintaining self-renewal and pluripotency. The present experiments were designed to test whether blockers of these signaling pathways enhance ACh cell content in the presence of LIF…

Saccharomyces cerevisiae yeast strains from the Linosa Island

2013

Protective effect of adenylate deaminase (from Penicillium lanoso-viride) against acute infections in mice

1996

We examined the effects of the immunomodulator-adenylate deaminase (E.C. 3.5.4.6) from Penicillium lanoso-viride on experimental mice infections. Prophylactic intraperitoneal administration of adenylate deaminase (ADA) increased survival time and numbers of survivors after infection with Salmonella typhimurium, Pseudomonas aeruginosa and influenza A (H3N2) virus. Protection against influenza virus after intranasal ADA application was also observed. The influence of ADA was time and dose dependent. The most pronounced protection was obtained by administration of 3 U ADA/mice 24 h prior to infection. ADA had no antibiotic effect against these bacterial strains. Protective effects of ADA were …

The Mediterranean Sanctuary for the Protection of Marine Mammals

1999

Tras una breve descripción de la única zona declarada como Santuario Mediterráneo para la protección de los mamíferos marinos, el presente trabajo comenta algunos aspectos jurídicos relativos a este Santuario marino. En primer lugar, centro la atención en la forma cómo se estableció este Santuario marino. Tras diversas iniciativas de diferentes organizaciones no gubernamentales, Italia, Francia y Mónaco establecieron unilateralmente este Santuario marino en sus respectivas legislaciones nacionales y, posteriormente, estos mismos tres Estados adoptaron un convenio internacional hacia este objetivo. Este instrumento internacional se conoce como la Declaración conjunta por la que se establece …

Seed germination in Sarcopoterium spinosum (L.) Spach from South-Eastern Sicily

2012

Sarcopoterium spinosum (L.) Spach is a nanophanerophyte whose presence in Sicily is limited to the South-East of the island. A study on seed germination behaviour of seeds collected from some populations indicates low viability of seedlings which could seriously put the long-term survival of these populations at risk.

Measurement ofΥ(1S+2S+3S)production inp+pand Au + Au collisions atsNN=200GeV

2015

Measurements of bottomonium production in heavy-ion and p + p collisions at the Relativistic Heavy Ion Collider (RHIC) are presented. The inclusive yield of the three states, (1S + 2S + 3S), was measured in the PHENIX experiment via electron-positron decay pairs at midrapidity for Au + Au and p + p collisions at root sNN = 200 GeV. The (1S + 2S + 3S) -> e(+)e(-) differential cross section at midrapidity was found to be B(ee)d sigma/dy = 108 +/- 38 (stat) +/- 15 (syst) +/- 11 (luminosity) pb in p + p collisions. The nuclear modification factor in the 30% most central Au + Au collisions indicates a suppression of the total. state yield relative to the extrapolation from p + p collision data. …

Synergy and Antagonism of Active Constituents of ADAPT-232 on Transcriptional Level of Metabolic Regulation of Isolated Neuroglial Cells

2013

Gene expression profiling was performed on the human neuroglial cell line T98G after treatment with adaptogen ADAPT-232 and its constituents - extracts of Eleutherococcus senticosus root, Schisandra chinensis berry, and Rhodiola rosea root as well as several constituents individually, namely, eleutheroside E, schizandrin B, salidroside, triandrin, and tyrosol. A common feature for all tested adaptogens was their effect on G-protein-coupled receptor signaling pathways, i.e., cAMP, phospholipase C (PLC), and phosphatidylinositol signal transduction pathways. Adaptogens may reduce the cAMP level in brain cells by down-regulation of adenylate cyclase gene ADC2Y and up-regulation of phosphodiest…

Consumer Demand for Environmental, Social, and Ethical Information in Fishery and Aquaculture Product Labels

2022

[EN] Customers' attention to sustainability labels in fishery and aquaculture products (FAPs) has been increasing in the last decades, and the industry has adapted to this growing interest by adopting fish ecolabels. However, there is a growing interest to widen the sustainability concept to include the social and ethical information of the fishery and aquaculture industry and to go further from the voluntary approach on the labeling of these aspects in FAPs. For this reason, using data from 2021 Eurobarometer and using machine learning techniques, we disentangle the characteristics of the FAP buyers that consider the importance of environmental impact, ethical, and social information appea…

Combined D0 measurements constraining theCP-violating phase and width difference in theBs0system

2007

We combine the D0 measurement of the width difference between the light and heavy B-s(0) mass eigenstates and of the CP-violating mixing phase determined from the time-dependent angular distributions in the B-s(0)-> J/psi phi decays along with the charge asymmetry in semileptonic decays also measured with the D0 detector. With the additional constraint from the world average of the flavor-specific B-s(0) lifetime, we obtain Delta Gamma(s)equivalent to(Gamma(L)-Gamma(H))=0.13 +/- 0.09 ps(-1) and vertical bar phi(s)vertical bar=0.70(-0.47)(+0.39) or Delta Gamma(s)=-0.13 +/- 0.09 ps(-1) and vertical bar phi(s)vertical bar=2.44(-0.39)(+0.47). The data sample corresponds to an integrated luminos…

Exclusive Branching-Fraction Measurements of SemileptonicτDecays into Three Charged Hadrons, intoφπ−ντ, and intoφK−ντ

2008

Using a data sample corresponding to an integrated luminosity of 342 fb(-1) collected with the BABAR detector at the SLAC PEP-II electron-positron storage ring operating at a center-of-mass energy near 10.58 GeV, we measure B(tau(-)->pi(-)pi(-)pi(+)nu(tau)(ex.K-S(0)))=(8.83 +/- 0.01 +/- 0.13)%, B(tau(-)-> K-pi(-)pi(+)nu(tau)(ex.K-S(0)))=(0.273 +/- 0.002 +/- 0.009)%, B(tau(-)-> K-pi K--(+)nu(tau))=(0.1346 +/- 0.0010 +/- 0.0036)%, and B(tau(-)-> K-K-K+nu(tau))=(1.58 +/- 0.13 +/- 0.12)x10(-5), where the uncertainties are statistical and systematic, respectively. These include significant improvements over previous measurements and a first measurement of B(tau(-)-> K-K-K+nu(tau)) in which no re…