Search results for "iNOS"

Nuclear liquid-gas phase transition and supernovae evolution

2004

It is shown that the large density fluctuations appearing at the onset of the first order nuclear liquid-gas phase transition can play an important role in the supernovae evolution. Due to these fluctuations, the neutrino gas may be trapped inside a thin layer of matter near the proto-neutron star surface. The resulting increase of pressure may induce strong particle ejection a few hundred milliseconds after the bounce of the collapse, contributing to the revival of the shock wave. The Hartree-Fock+RPA scheme, with a finite-range nucleon-nucleon effective interaction, is employed to estimate the effects of the neutrino trapping due to the strong density fluctuations, and to discuss qualitat…

Multiwavelength afterglow light curves from magnetized gamma-ray burst flows

2010

We use high-resolution relativistic magnetohydrodynamics simulations coupled with a radiative transfer code to compute multiwavelength afterglow light curves of magnetized ejecta of gamma-ray bursts interacting with a uniform circumburst medium. The aim of our study is to determine how the magnetization of the ejecta at large distance from the central engine influences the afterglow emission, and to assess whether observations can be reliably used to infer the strength of the magnetic field. We find that, for typical parameters of the ejecta, the emission from the reverse shock peaks for magnetization (σ 0 ~ 0.01-0.1 of the flow, and that it is greatly suppressed for higher σ 0 . The emissi…

CARATTERIZZAZIONE MORFOLOGICA E GENETICA DI POPOLAZIONI DI CAPPARIS SPINOSA L. IN SICILIA.

2011

AtPGAP1 functions as a GPI inositol-deacylase required for efficient transport of GPI-anchored proteins

2021

Abstract Glycosylphosphatidylinositol (GPI)-anchored proteins (GPI-APs) play an important role in a variety of plant biological processes including growth, stress response, morphogenesis, signaling, and cell wall biosynthesis. The GPI anchor contains a lipid-linked glycan backbone that is synthesized in the endoplasmic reticulum (ER) where it is subsequently transferred to the C-terminus of proteins containing a GPI signal peptide by a GPI transamidase. Once the GPI anchor is attached to the protein, the glycan and lipid moieties are remodeled. In mammals and yeast, this remodeling is required for GPI-APs to be included in Coat Protein II-coated vesicles for their ER export and subsequent t…

Function of AtPGAP1 in GPI anchor lipid remodeling and transport to the cell surface of GPI-anchored proteins

2021

ABSTRACTGPI-anchored proteins (GPI-APs) play an important role in a variety of plant biological processes including growth, stress response, morphogenesis, signalling and cell wall biosynthesis. The GPI-anchor contains a lipid-linked glycan backbone that is synthesized in the endoplasmic reticulum (ER) where it is subsequently transferred to the C-terminus of proteins containing a GPI signal peptide by a GPI transamidase. Once the GPI anchor is attached to the protein, the glycan and lipid moieties are remodelled. In mammals and yeast, this remodelling is required for GPI-APs to be included in Coat Protein II (COPII) coated vesicles for their ER export and subsequent transport to the cell s…

Characterization of a glycosylphosphatidylinositol-bound cell-wall protein (GPI-CWP) in Yarrowia lipolytica.

2004

The structure and composition of the cell wall of yeast has so far been studied mainly in Saccharomyces cerevisiae. It is basically made up of three components: beta-glucans, chitin and mannose-containing glycoproteins, also called mannoproteins. Most covalently bound cell-wall mannoproteins belong to the so-called glycosylphosphatidylinositol cell-wall protein (GPI-CWP) family, cell-wall proteins that are bound through the remnant of a GPI residue to 1,6-beta-glucan. The non-conventional yeast Yarrowia lipolytica shares Generally Regarded As Safe (GRAS) status with S. cerevisiae, has some industrial applications and is increasingly being proposed as a host for the production of recombinant…

Al-27 and Si-29 Solid-State NMR Characterization of Calcium-Aluminosilicate-Hydrate

2012

International audience; Calcium silicate hydrate (C-S-H) is the main constituent of hydrated cement paste and determines its cohesive properties. Because of the environmental impact of cement industry, it is more and more common to replace a part of the clinker in cement by secondary cementitious materials (SCMs). These SCMs are generally alumina-rich and as a consequence some aluminum is incorporated into the C-S-H. This may have consequences on the cohesion and durability of the material, and it is thus of importance to know the amount and the location of Al in C-S-H and what the parameters are that control these features. The present paper reports the Si-29 and Al-27 MAS NMR analyses of …

Surface AFM microscopy of unworn and worn samples of silicone hydrogel contact lenses

2008

Abstract: Purpose. To evaluate the qualitative and quantitative topographic changes in the surface of worn contact lenses (CLs) of different materials using atomic force microscopy (AFM). Methods. The topography of five different CL materials was evaluated withAFM over a surface of 25 lm2 according to previously published experimental setup. Average roughness (Ra) and root mean square (Rms) values were obtained for unworn and worn samples. Results. The Ra value increased for balafilcon A (11.62–13.68 nm for unworn and worn samples, respectively), lotrafilcon A (3.67–15.01 nm for unworn and worn samples, respectively), lotrafilcon B (4.08–8.42 nm for unworn and worn samples, respectively), g…

La conservación de los recursos vivos marinos antárticos en la Convención de Canberra de 1980

1989

l. INTRODUCCIÓN.- II. LA CONSERVACIÓN DE LOS RECURSOS MARINOS VIVOS EN LA ANTÁRTIDA.- III. VENTAJAS DE ESTE PLANTEAMIENTO CONSERVACIONISTA.- IV. INCONVENIENTES A LOS CONSERVACIÓN DE LOS RECURSOS VIVOS MARINOS ANTÁRTICOS: 1. Los recursos marinos vivos protegidos; 2. Soberanía y jurisdicción en la Antártida; 3. Necesidad de información científica; 4. Procedimiento de adopción de las medidas de conservación; 5. Las medidas de conservación; 6. El control de la aplicación de estas medidas; 7. El relativismo de los tratados; 8. Daños al medio ambiente antártico por otras actividades.- V. CONCLUSIONES.

Transcriptomic identification of miR-205 target genes potentially involved in metastasis and survival of cutaneous malignant melanoma

2020

AbstractCutaneous melanoma is an aggressive neoplasm and is responsible for the majority of skin cancer deaths. Several miRNAs are involved in melanoma tumor progression. One of them is miR-205, the loss of which contributes to the development of melanoma metastasis. We evaluated whole-genome mRNA expression profiling associated with different miR-205 expression levels in melanoma cells. Differential expression analysis identified 243 differentially expressed transcripts including inositol polyphosphate 5′-phosphatase-like protein-1 (INPPL1) and BTB/POZ Domain-Containing Protein 3 (BTBD3). INPPL1 and BTBD3 were downregulated when melanoma cells expressed miR-205, indicating that these genes…