Search results for "iTED"

showing 10 items of 2408 documents

Country, Sex, and Parent Occupational Status: Moderators of the Continuity of Aggression from Childhood to Adulthood

2014

Using data from two American and one Finnish long-term longitudinal studies, we examined continuity of general aggression from age 8 to physical aggression in early adulthood (age 21–30) and whether continuity of aggression differed by country, sex, and parent occupational status. In all samples, childhood aggression was assessed via peer nominations and early adulthood aggression via self-reports. Multi-group structural equation models revealed significant continuity in aggression in the American samples but not in the Finnish sample. These relations did not differ by sex but did differ by parent occupational status: whereas there was no significant continuity among American children from …

AdultEmploymentMaleParentsaggressionstructural equation modellongitudinal studycross-nationalArticleUnited StatesAggressionCohort Studiesoccupational statusYoung AdultChild DevelopmentSex FactorsjatkuvuusHumansFemaleLongitudinal StudiesProspective StudiesChildFinland
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Addressing the impact of SARS-CoV-2 infection in persons with congenital bleeding disorders: The Italian MECCOVID-19 study

2021

congenital bleeding disorders

AdultInheritedMalePediatricsmedicine.medical_specialty2019-20 coronavirus outbreakCoronavirus disease 2019 (COVID-19)congenital bleeding disorderscongenital bleeding disorderSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)haemophiliaHemorrhageHaemophiliaLetter to the EditorsSARS‐CoV‐2Young AdultBlood Coagulation Disorders InheritedCOVID‐19congenital bleeding disorders; COVID-19; epidemiology; haemophilia; observational study; SARS-CoV-2; Adult; Aged; Blood Coagulation Disorders Inherited; COVID-19; Child Preschool; Disease Management; Female; Hemorrhage; Humans; Italy; Male; Middle Aged; SARS-CoV-2; Young AdultEpidemiologymedicineHumansYoung adultDisease management (health)ChildPreschoolLetter to the EditorGenetics (clinical)Agedbusiness.industrySARS-CoV-2COVID-19Disease ManagementHematologyGeneral MedicineBlood Coagulation DisordersMiddle Agedmedicine.diseaseItalySARS-CoV-2.Child PreschoolObservational studyepidemiologyobservational studyFemalebusiness
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Early experiences from one of the first treatment programs for chronic hepatitis B in sub-Saharan Africa

2017

Treatment for chronic hepatitis B (CHB) is virtually absent in sub-Saharan Africa. Here we present early experiences from a pilot program for treatment of CHB in Ethiopia. Adults (≥18 years) with CHB were included in a cohort study at St. Paul’s Hospital Millennium Medical College, Addis Ababa, from February 2015. The baseline assessment included liver function tests, viral markers and transient elastography (Fibroscan 402, Echosense, France). Logistic regression models were used to identify predictors of fibrosis. Tenofovir disoproxil fumarate (TDF) was initiated based on the European Association for the Study of the Liver (EASL) criteria, with some modifications. The initial 300 patients …

AdultLiver CirrhosisMaleHepatitis B virusmedicine.medical_specialtyCirrhosisPilot ProjectsAntiviral therapyAntiviral Agentslcsh:Infectious and parasitic diseasesCohort StudiesYoung Adult03 medical and health sciencesHepatitis B Chronic0302 clinical medicinePregnancyInterquartile rangeInternal medicinemedicineHumanslcsh:RC109-216Hepatitis B e Antigens030212 general & internal medicinePregnancy Complications InfectiousTenofovirAIDS-Related Opportunistic Infectionsmedicine.diagnostic_testCoinfectionbusiness.industryAlanine TransaminaseMiddle AgedViral LoadHepatitis Bmedicine.diseaseResource-limited settingsInfectious DiseasesHBeAgAfricaImmunologyFemale030211 gastroenterology & hepatologyEthiopiaTransient elastographyLiver function testsbusinessViral loadBiomarkersResearch ArticleCohort study
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Treatment of chronic hepatitis B in sub-Saharan Africa: 1-year results of a pilot program in Ethiopia

2018

Background The World Health Organization has set an ambitious goal of eliminating viral hepatitis as a major public health threat by 2030. However, in sub-Saharan Africa, antiviral treatment of chronic hepatitis B (CHB) is virtually unavailable. Herein, we present the 1-year results of a pilot CHB treatment program in Ethiopia. Methods At a public hospital in Addis Ababa, CHB patients were treated with tenofovir disoproxil fumarate based on simplified eligibility criteria. Baseline assessment included liver function tests, viral markers, and transient elastography (Fibroscan). Changes in laboratory markers were analyzed using Wilcoxon signed-rank tests. Adherence to therapy was measured by …

AdultLiver CirrhosisMalemedicine.medical_specialtyAdolescentEpidemiologylcsh:MedicinePilot ProjectsAntiviral therapymedicine.disease_causeAntiviral AgentsYoung Adult03 medical and health sciencesHepatitis B Chronic0302 clinical medicineChronic hepatitisInternal medicineEpidemiologymedicineHumansPilot program030212 general & internal medicineViral hepatitisTenofovirHepatitis B virusmedicine.diagnostic_testbusiness.industryPublic healthlcsh:RGeneral MedicineMiddle AgedViral Loadmedicine.diseaseResource-limited settingsTreatment Adherence and ComplianceTreatment OutcomeFemale030211 gastroenterology & hepatologyEthiopiaTransient elastographybusinessLiver function testsViral hepatitisBiomarkersFollow-Up StudiesResearch ArticleBMC Medicine
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Predictors of mortality in patients under treatment for chronic hepatitis B in Ethiopia: a prospective cohort study

2019

Abstract Background Antiviral treatment for chronic hepatitis B (CHB) is largely unavailable in sub-Saharan Africa; hence, little is known about the prognosis after initiating treatment in African CHB patients. In this study we aimed to assess predictors of mortality in one of the largest CHB cohorts in sub-Saharan Africa. Methods Two-hundred-and-seventy-six CHB patients who started treatment with tenofovir disoproxil fumarate at a public hospital in Ethiopia between March 18, 2015, and August 1, 2017, were included in this analysis. Patients were followed up until October 1, 2017, and deaths were ascertained through hospital records and telephone interview with relatives. Decompensated cir…

AdultLiver CirrhosisMalemedicine.medical_specialtyTime FactorsSurvivalAdolescentEpidemiologyPhysical examinationAntiviral therapyAntiviral AgentsBody Mass Index03 medical and health sciencesYoung Adult0302 clinical medicineHepatitis B ChronicInterquartile rangeRisk FactorsInternal medicineEpidemiologyMedicineHumansProspective Studieslcsh:RC799-869Prospective cohort studyTenofovirProportional Hazards Modelsmedicine.diagnostic_testbusiness.industryHazard ratioGastroenterologyAge FactorsGeneral MedicineHepatitis BHepatologyMiddle Agedmedicine.diseaseHepatitis BResource-limited settingsSurvival RateVDP::Medisinske Fag: 700::Helsefag: 800030220 oncology & carcinogenesislcsh:Diseases of the digestive system. Gastroenterology030211 gastroenterology & hepatologyFemaleEthiopiabusinessBody mass indexResearch Article
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HRCT and scleroderma: semiquantitative evaluation of lung damage and functional abnormalities.

2007

This study sought to validate the Warrick score in the assessment of lung involvement in systemic sclerosis (SSc) and correlate the results with functional abnormalities. In addition, we propose the use of high resolution computed tomography (HRCT) indices of alveolitis and fibrosis to discriminate between different stages of the disease.Thirty-one patients with SSc (16 with the diffuse form and 15 with the limited form) underwent functional and HRCT evaluations of the lung. The semiquantitative evaluation of radiological involvement, as proposed by Warrick, provides a score for each lesion based on the severity and the extent of the pulmonary damage. In addition to the total score, indices…

AdultLung DiseasesMalemedicine.medical_specialtyHigh-resolution computed tomographyGastroenterologySensitivity and SpecificitySeverity of Illness IndexLesionFibrosisDLCOScleroderma LimitedInternal medicineForced Expiratory VolumePulmonary fibrosisSeverity of illnessmedicineHumansRadiology Nuclear Medicine and imagingLung volumesAgedLungScleroderma Systemicmedicine.diagnostic_testbusiness.industryTotal Lung CapacityGeneral Medicinerespiratory systemMiddle Agedmedicine.diseaseFibrosisrespiratory tract diseasesRespiratory Function TestsPulmonary Alveolimedicine.anatomical_structureScleroderma DiffuseFemalemedicine.symptomlung scleroderma HRCTNuclear medicinebusinessTomography X-Ray ComputedLa Radiologia medica
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Growth hormone replacement in adults:Real-world data from two large studies in US and Europe

2020

Objective: This report describes the effectiveness and safety of growth hormone replacement in 3180 adult patients with growth hormone deficiency followed-up for 0.0–12.2 years in two completed, complementary, non-interventional, multicentre studies, NordiNet® International Outcome Study (IOS) (NCT00960128) and the American Norditropin® Studies: Web-Enabled Research (ANSWER) Program (NCT01009905). Design: In both studies, Norditropin® (somatropin; Novo Nordisk A/S, Denmark) was administered at the discretion of the treating physician and according to routine practice. We present data on baseline characteristics, growth hormone dose, safety data and change from baseline in waist circumferenc…

AdultMale0301 basic medicineIGF-I SDSPediatricsmedicine.medical_specialtyWaistHormone Replacement TherapyEndocrinology Diabetes and MetabolismANSWER Program030209 endocrinology & metabolismEffectivenessGrowth hormoneNordiNet® International Outcome Study (IOS)Body compositionHypopituitarismBody Mass IndexGrowth hormone deficiency03 medical and health sciences0302 clinical medicineEndocrinologyElectric ImpedancemedicineHumansGrowth hormone replacementAgedAdult patientsHuman Growth Hormonebusiness.industryMiddle Agedmedicine.diseaseRecombinant ProteinsUnited StatesReal-world dataEuropeClinical Practice030104 developmental biologyGrowth hormone deficiency in adultsBaseline characteristicsBody CompositionFemaleWaist CircumferenceSafetybusinessReal world dataBody mass index
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Monitoring recent trends: The prevalence of disclosure of sexual abuse in a representative sample of the German population based on indicator 16.2.3 …

2019

Abstract Background The monitoring of trends is important. The United Nations (UN) have defined indicators to monitor the proportion of young men and women who have experienced sexual abuse before the age of 18 (Indicator 16.2.3) as part of their global agenda, the Sustainable Development Goals (SDG). Objective To examine recent trends in the disclosure of sexual abuse based on the indicator 16.2.3 of the SDG. Participants and setting A total of 7530 participants across Germany (51.1% female) were included. The participants were between 14 and 94 years old. Methods Three representative surveys were conducted using identical methods in 2010 (N = 2504), 2016 (N = 2510) and 2018 (N = 2516). A …

AdultMale050103 clinical psychologyAdolescentUnited NationsPrevalencePoison controlDisclosureSuicide preventionOccupational safety and healthYoung AdultGermanySurveys and QuestionnairesInjury preventionPrevalenceDevelopmental and Educational PsychologyHumansMedicine0501 psychology and cognitive sciencesbusiness.industry05 social sciencesChild Abuse SexualSustainable DevelopmentPsychiatry and Mental healthSexual abuseChild sexual abusePediatrics Perinatology and Child HealthCohortFemalebusiness050104 developmental & child psychologyDemographyChild Abuse & Neglect
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Psychometric properties of measures of sociocultural influence and internalization of appearance ideals across eight countries

2020

The aim of the current study was to examine the psychometric properties of two well-established measures of sociocultural influence and internalization of the thin/low body fat ideal and muscular ideal. Data from 6272 emerging adults (68.9 % female), aged 18-30 years from Australia, Belgium, Canada, China, Italy, Japan, Spain, and the U.S. were included in this study. Participants completed measures of pressure from mother, fathers, peers, and media, to both increase muscles and lose weight, as well as internalization of the thin/low body fat ideal and muscular ideal. Overall, support for partial invariance was found across the scales. In addition, group level differences were found between…

AdultMale050103 clinical psychologyCanadaChinaSocial PsychologyAdolescentPsychometricsmedia_common.quotation_subjectMothers050109 social psychologySettore M-PSI/08 - PSICOLOGIA CLINICAPeer GroupDevelopmental psychologyBody Mass Index[SHS]Humanities and Social SciencesYoung AdultSex FactorsBelgiumJapanSurveys and QuestionnairesHumans0501 psychology and cognitive sciences10. No inequalitySociocultural evolutionInternalizationGroup levelSocioeconomic statusGeneral PsychologyApplied Psychologymedia_commonIdeal (set theory)05 social sciencesBody WeightAge FactorsAustraliaUnited StatesSociocultural influenceBody imageItalySpainFemalePsychologyBody mass indexInternalizationPressures
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Assessment of EVAR Complications using CIRSE Complication Classification System in the UK Tertiary Referral Centre: A ∼6-Year Retrospective Analysis …

2021

Purpose: To retrospectively analyse complications in endovascular aortic repair (EVAR) interventions and evaluate if the CIRSE (Cardiovascular and Interventional Radiological Society of Europe) complication classification system is appropriate as a standardized classification tool for EVAR patients. Materials and Methods: Demographic, procedural and complication data in 719 consecutive patients undergoing EVAR at one institution from January 2014 to October 2019 were retrospectively reviewed. Data (imaging reports, procedural reports, nurse notes, discharge summary reports) were collected consulting the electronic patient record system (EPR) of the hospital and cleaned and stored in a Micro…

AdultMaleAccess-site complicationmedicine.medical_specialtyTime FactorsAdditional treatmentEndoleakEndovascular aortic repair (EVAR)Tertiary referral centreComplication grading scalePopulationVascular accessRadiology InterventionalSeverity of Illness Index030218 nuclear medicine & medical imagingTertiary Care Centers03 medical and health sciencesYoung Adult0302 clinical medicinePostoperative ComplicationsmedicineRetrospective analysisHumansRadiology Nuclear Medicine and imagingIn patienteducationReferral and ConsultationSocieties MedicalAgedRetrospective StudiesAged 80 and overeducation.field_of_studyCIRSE complication classification systemmedicine.diagnostic_testbusiness.industryGeneral surgeryEndovascular ProceduresInterventional radiologyMiddle AgedUnited KingdomAortic AneurysmEuropeReporting systemTreatment OutcomeRadiological weaponFemaleCardiology and Cardiovascular MedicineComplicationbusinessCardiovascular and interventional radiology
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