Search results for "iTED"
showing 10 items of 2408 documents
¿Estados Unidos de Europa? Mapeo y diseño de constituciones para Europa
2020
En los últimos tiempos, académicos, intelectuales públicos, movimientos políticos y sociales y destacados líderes políticos europeos de diferentes orientaciones ideológicas han hecho un llamamiento a la creación de unos Estados Unidos de Europa. Desde su punto de vista, enfrentar la crisis de legitimidad de la UE requiere una renovación democrática a través de un proceso constituyente. Sin embargo, estas declaraciones no han sido acompañadas por un diseño específico sobre cómo instituir esta nueva Constitución Europea. Con el objeto de discutir las posibles vías de poner en práctica esta idea, este artículo presenta las principales formulaciones del poder constituyente europeo y su traducci…
Archibald Philip Primrose, V Earl of Rosebery 1894-1895 - Un “imperialista liberale”
2020
.La figura di Archibald Philip Primrose, complessa e contraddittoria, può considerarsi lo specchio dell’epoca in cui visse, a cavallo delle grandi rivoluzioni e delle profonde trasformazioni che avrebbero caratterizzato il secolo del ‘900, Uomo di grande cultura e di rara brillantezza intellettuale, fu partecipe dei governi di W. Gladstone, fino a divenire Premier nel 1894, per volere della Regina Vittoria. La sua natura aristocratica ma aperta lo portò, prima degli altri liberali, a percepire l’esigenza di un cambiamento di atteggiamento della Gran Bretagna verso le sue colonie, proponendosi come guida gentile e non oppressiva, espressione di un imperialismo moderno e sensato. Allo stesso …
BBS1 Mutations in a Wide Spectrum of Phenotypes Ranging From Nonsyndromic Retinitis Pigmentosa to Bardet-Biedl Syndrome
2012
OBJECTIVE: To investigate the involvement of the Bardet-Biedl syndrome (BBS) gene BBS1 p.M390R variant in nonsyndromic autosomal recessive retinitis pigmentosa (RP). METHODS: Homozygosity mapping of a patient with isolated RP was followed by BBS1 sequence analysis. We performed restriction fragment length polymorphism analysis of the p.M390R allele in 2007 patients with isolated RP or autosomal recessive RP and in 1824 ethnically matched controls. Patients with 2 BBS1 variants underwent extensive clinical and ophthalmologic assessment. RESULTS: In an RP proband who did not fulfill the clinical criteria for BBS, we identified a large homozygous region encompassing the BBS1 gene, which carrie…
Intelligence in DSM-IV combined type attention-deficit/hyperactivity disorder is not predicted by either dopamine receptor/transporter genes or other…
2008
Contains fulltext : 69677.pdf (Publisher’s version ) (Closed access) A major goal of genetic studies of attention deficit hyperactivity disorder (ADHD) is to identify individual characteristics that might help segregate the disorder's inherent heterogeneity. [Mill et al. (2006); Arch Ger Psychiatry 63:462-469] recently reported a potentially important association between two dopamine-related risk polymorphisms (DRD4 variable number tandem repeat (VNTR) in exon 3 and DAT1 VNTR in the 3' UTR) and lowered IQ in ADHD. The objective of the current study was to replicate the [Mill et al. (2006); Arch Ger Psychiatry 63:462-469] findings in a clinical sample and to extend the analysis to a large ra…
Genetic heterogeneity in ADHD: DAT1 gene only affects probands without CD
2008
Contains fulltext : 70183.pdf (Publisher’s version ) (Closed access) Previous studies have found heterogeneous association between DAT1-3'-UTR-VNTR and attention deficit hyperactivity disorder (ADHD). Various proportions of conduct disorder (CD) comorbidity in their ADHD samples may partially explain the observational discrepancies. Evidence for this comes from family and twin studies which found ADHD probands with CD (ADHD + CD) are genetically different from those without CD (ADHD - CD). Genotypes of 20 DAT1 markers were analyzed in 576 trios, consisting of 141 ADHD + CD and 435 ADHD - CD. In addition to the classical TDT test, a specific genetic heterogeneity test was performed to identi…
A homozygous mutation in the TUB gene associated with retinal dystrophy and obesity.
2013
Inherited retinal dystrophies are a major cause of childhood blindness. Here, we describe the identification of a homozygous frameshift mutation (c.1194_1195delAG, p.Arg398Serfs*9) in TUB in a child from a consanguineous UK Caucasian family investigated using autozygosity mapping and whole-exome sequencing. The proband presented with obesity, night blindness, decreased visual acuity, and electrophysiological features of a rod cone dystrophy. The mutation was also found in two of the proband's siblings with retinal dystrophy and resulted in mislocalization of the truncated protein. In contrast to known forms of retinal dystrophy, including those caused by mutations in the tubby-like protein …
English and French Modes of Regulation of the Education System : a comparison
2003
03069; International audience; This paper describes English and French modes of regulation of the educational system, stressing the contrast between them (regulation by process versus regulation by outcomes), while their goals and organisation prove rather more convergent over the last 30 years. It tries to assess the correspondence between those two ways of operating and what we know about the functioning of organisations like schools. From that point of view, the French system fits the economic theory of organisation less well than the English one, so that some contradictions and tensions are predictable. Last, it looks for some relationhip with indicators of effectiveness, equity and soc…
The good process or the great illusion? A spatial perspective on public participation in Danish municipal wind turbine planning
2021
This paper explores the nature of public participation in Danish municipal wind power planning. Although the procedure for involving citizens embedded in the environmental impact assessment (EIA) procedure for wind power projects is often praised for its participatory character, the approach is not without problems. In this paper, we identify the limitations and potentials of the public space provided for citizen involvement. By means of Gaventa’s terminology suggesting a continuum of public spaces for participation, the paper shows how the planning process can be approached from different spatial perspectives – each of them illuminating different forms of power, resistance and opportunitie…
The impact of COVID-19 on the practice of Oral and Maxillofacial Pathology in the United States and Canada.
2022
The COVID-19 pandemic has significantly disrupted the delivery of healthcare, including oral healthcare services. The restrictions imposed for mitigating spread of the virus forced dental practitioners to adopt significant changes in their workflow pattern. The aim of this study was to investigate the impact of the pandemic on the practice of oral and maxillofacial pathology in two countries in regard to educational activities, and clinical and diagnostic pathology services.An online questionnaire was distributed to oral and maxillofacial pathologists in the United States and Canada. The survey was designed by combining dichotomous, multiple choice, and Likert response scale questions. Stat…
Power of Paradox: Grassroots Organizations’ Legitimacy Strategies Over Time
2021
Fringe stakeholders with limited resources, such as grassroots organizations (GROs), are often ignored in business and society literature. We develop a conceptual framework and a set of propositions detailing how GROs strategically gain legitimacy and influence over time. We argue that GROs encounter specific paradoxes over the emergence, development, and resolution of an issue, and they address these paradoxes using cognitive, moral, and pragmatic legitimacy strategies. While cognitive and moral strategies tend to be used consistently, the flexible and paradoxical use of pragmatic strategies has important consequences, both for GROs’ legitimacy and for their potential influence over powerf…