Search results for "iTED"

showing 10 items of 2408 documents

Stability and disassembly properties of human naïve Hsp60 and bacterial GroEL chaperonins.

2015

Human Hsp60 chaperonin and its bacterial homolog GroEL, in association with the corresponding co-chaperonins Hsp10 and GroES, constitute important chaperone systems promoting the proper folding of several mitochondrial proteins. Hsp60 is also currently described as a ubiquitous molecule with multiple roles both in health conditions and in several diseases. Naïve Hsp60 bearing the mitochondrial import signal has been recently demonstrated to present different oligomeric organizations with respect to GroEL, suggesting new possible physiological functions. Here we present a combined investigation with circular dichroism and small-angle X-ray scattering of structure, self-organization, and sta…

guanidiniun chloride0301 basic medicineGuanidinium chlorideSmall AngleCircular dichroismBiophysicsmacromolecular substancesBiochemistryGroELChaperoninScatteringMitochondrial Proteins03 medical and health scienceschemistry.chemical_compoundBacterial ProteinsX-Ray DiffractionScattering Small AngleHumansGuanidinebiologyProtein StabilityCircular DichroismOrganic ChemistryTemperatureGroESSAXSChaperonin 60Hsp60GroELSettore FIS/07 - Fisica Applicata(Beni Culturali Ambientali Biol.e Medicin)CDcited By 5enzymes and coenzymes (carbohydrates)Denaturation030104 developmental biologychemistryBiochemistryChaperone (protein)biological sciencesbiology.proteinCD; Denaturation; GroEL; Guanidinium chloride; Hsp60; SAXS; Bacterial Proteins; Chaperonin 60; Circular Dichroism; Humans; Mitochondrial Proteins; Protein Stability; Scattering Small Angle; Temperature; X-Ray DiffractionbacteriaHSP60Guanidinium chlorideBiophysical chemistry
researchProduct

Combination vaccines containing DTPa–Hib: impact of IPV and coadministration of CRM197 conjugates

2008

Vaccination with diphtheria-tetanus-acellular pertussis (DTPa)-Haemophilus influenzae type b (Hib) combinations generally elicits anti-polyribosyl-ribitol-phosphate (PRP) antibody concentrations of more than 0.15 microg/ml, a criterion that is linked to the protection of infants against Hib disease. In the UK, vaccination with DTPa3-Hib elicited atypically low anti-PRP antibody levels and was associated with breakthrough Hib cases. While the absence of a toddler booster is considered to be a key factor explaining the lowered control of Hib disease, we propose that the coadministration of serogroup C Neisseria meningitidis conjugate vaccine (MenC)-CRM197, which coincided with the introductio…

health care facilities manpower and servicesImmunologyDiphtheria-Tetanus-acellular Pertussis Vaccinesmedicine.disease_causecomplex mixturesBacterial ProteinsAntigenConjugate vaccineImmunityDrug DiscoveryHumansMedicineDiphtheria-Tetanus-acellular Pertussis VaccinesHaemophilus VaccinesPharmacologybusiness.industryNeisseria meningitidisToxoidHepatitis Bbacterial infections and mycosesmedicine.diseaseVirologyUnited Kingdomcarbohydrates (lipids)VaccinationPoliovirus Vaccine InactivatedImmunologybacteriaMolecular MedicinebusinessExpert Review of Vaccines
researchProduct

Coastal high-frequency radars in the Mediterranean - Part 2: Applications in support of science priorities and societal needs

2022

The Mediterranean Sea is a prominent climate-change hot spot, with many socioeconomically vital coastal areas being the most vulnerable targets for maritime safety, diverse met-ocean hazards and marine pollution. Providing an unprecedented spatial and temporal resolution at wide coastal areas, high-frequency radars (HFRs) have been steadily gaining recognition as an effective land-based remote sensing technology for continuous monitoring of the surface circulation, increasingly waves and occasionally winds. HFR measurements have boosted the thorough scientific knowledge of coastal processes, also fostering a broad range of applications, which has promoted their integration in coastal ocean …

high-frequency radars ; Mediterranean ; reviewIntracoastal waterways -- Mediterranean regionhigh-frequency radar (HFR) sea surface currents ocean wavesSettore ICAR/02 - Costruzioni Idrauliche E Marittime E IdrologiaMaritime lawUnited Nations Convention on the Law of the Sea (1982 December 10)Green New Deal -- European Union countriesGeneral MedicineRemote sensingEnvironmental monitoring -- Mediterranean regionGeophysics[SDU]Sciences of the Universe [physics]Coastal zone management -- Mediterranean regionCoastal ecosystem health[SDU.STU.OC]Sciences of the Universe [physics]/Earth Sciences/Oceanography
researchProduct

Modelling competences and anticipating the future competence needs in the forest sector

2018

This explorative study examined practices of competence modelling in the forest sector organisations and how organisations anticipate changes in competence needs in the future. Semi-structured in-depth interviews (n=10) were conducted amongst forest sector experts in Finland and data was analysed by thematic analysis. The findings showed that the practices of modelling competences were diverse, most frequently used ones being superior-subordinate review discussions and quantitative competence surveys. In addition to these formal systems, informal modelling, especially on the team level and in smaller companies was also frequent. Organisations used competence modelling for several human reso…

human resourcesKnowledge managementHigher educationRESOURCEScompetence modellingmetsäalaUNITED-STATESHIGHER-EDUCATIONINDUSTRYmetsätyöntekijätta516ammattitaitolcsh:ForestryHuman resourcesCompetence (human resources)OUTCOMES4112 Forestrybusiness.industryEcological ModelingForestryPERFORMANCEfuture needsta4112Work lifeforest sectorkompetenssihenkilöstöresurssitlcsh:SD1-669.5work lifebusinessPsychology
researchProduct

Rhetoric in the American and Cuban palaver on human trafficking

2010

The purpose of the thesis is to understand how the anti-human trafficking dialogue in the Cuban-American context is used as medium to express national agendas. The research data were speeches delivered by representatives of the US and Cuban governments that specifically mentioned Cuba or the United States in addition to human trafficking. The broad categories that emerged in these speeches included religion, morality, children (youth), and gender. The rhetoric employed within each of these categories was examined to reveal how the palaver on human trafficking was used to promote American and Cuban agendas. It was found that the use of religious rhetoric is an effective tool for the American…

human traffickingrhetoricKuubaCubaihmiskaupparetoriikkaUnited StatesYhdysvallat
researchProduct

Time to wake up, sanoo senaattori Whitehouse

2018

Demokraattisenaattori Sheldon Whitehouse aloitti ilmastonmuutosta koskevien puheidensa sarjan Yhdysvaltain kongressissa vuonna 2012. Nyt hän on puhunut aiheesta 223 kertaa. Marraskuun välivaaleissa 2018 Whitehouse valittiin kolmannelle senaattorikaudelle selvällä äänten enemmistöllä. nonPeerReviewed

ilmastopolitiikkaparlamenttivaalitCongressmidterm electionssenaattoritYhdysvallatUnited States
researchProduct

The Design and Impacts of Individual Sanctions: Evidence From Elites in Côte d’Ivoire and Zimbabwe

2022

Since the 1990s, sanctions senders like the European Union, the United States, and the United Nations have been imposing visa bans and asset freezes on individuals as a key element of their sanctions packages. Notwithstanding the growing centrality that individual sanctions have acquired in international sanctions practice, little is known about the impact of sanctions listings on designees. Some researchers have scrutinised targeting choices, while others have explored the effects of sanctions on designees. However, no study has yet examined the fit between targeting choices and impacts on designees. First, we interrogate the theory of targeted sanctions to identify the expectations that i…

impact of sanctionsunited nationscôte d’ivoireUNESCO::CIENCIAS JURÍDICAS Y DERECHOtargeted sanctionszimbabweeuropean union
researchProduct

The United Nations Conference on the Human Environment.

2023

The United Nations Conference on the Human Environment. 1. Introduction. 2. The 1972 Stockholm Declaration. 3. The Action Plan for the Human Environment. 3. Consequences of the United Nations Conference on the Human Environment.

international environmental lawconference on the human environmentunited nationsUNESCO::CIENCIAS JURÍDICAS Y DERECHO::Derecho internacionalstockholm conference
researchProduct

INTERNATIONAL MIGRATION IN THE EUROPEAN UNION: EMIGRATION FROM LATVIA TO THE UNITED KINGDOM

2013

Elektroniskā versija nesatur pielikumus

international migration (Latvia United Kingdom)Emigrācija un imigrācijaĢeogrāfijamigrant social networksemigrationCilvēka ģeogrāfijaĢeogrāfijas un zemes zinātnes
researchProduct

Purposes and Principles of the United Nations Organization.

2023

Purposes and Principles of the United Nations Organization. 1. Introduction. 2. The Purposes of the United Nations. 3. The Principles of the United Nations.

international subjectivityUNESCO::CIENCIAS JURÍDICAS Y DERECHO::Derecho internacionalunited nations organizationpurposes and principlesUNOinternational law
researchProduct