Search results for "ikääntyminen"
showing 10 items of 427 documents
Genome-wide Association Analysis in Humans Links Nucleotide Metabolism to Leukocyte Telomere Length
2020
Leukocyte telomere length (LTL) is a heritable biomarker of genomic aging. In this study, we perform a genome-wide meta-analysis of LTL by pooling densely genotyped and imputed association results across large-scale European-descent studies including up to 78,592 individuals. We identify 49 genomic regions at a false dicovery rate (FDR) < 0.05 threshold and prioritize genes at 31, with five highlighting nucleotide metabolism as an important regulator of LTL. We report six genome-wide significant loci in or near SENP7, MOB1B, CARMIL1, PRRC2A, TERF2, and RFWD3, and our results support recently identified PARP1, POT1, ATM, and MPHOSPH6 loci. Phenome-wide analyses in >350,000 UK Biobank p…
Perceived barriers in the outdoor environment and development of walking difficulties in older people
2012
SIR—Older people with mobility limitations often report more barriers in their outdoor environment than people with intact mobility [1]. However, it is uncertain whether older people perceive their environment as problematic because of their mobility limitations or whether the environmental barriers precede incident mobility limitation, as most studies have been limited to cross-sectional analyses [2–5]. Only a few longitudinal studies have shown that barriers in the outdoor environment, such as poor street conditions, poor lighting and heavy traffic, increase the risk for overall functional loss [6, 7] and decrease physical activity participation [8]. More knowledge is needed about the cha…
Aging as a topic in a business magazine : an opportunity or threat for management?
2018
Purpose Recently, research on aging in the work-life context from the perspective of how to manage, support and retain an aging workforce has increased among management scholars, and therefore is contributing to the current societal need to extend work careers. The purpose of this paper is to analyze the articles discussing aging in the work-life context in the Finnish business magazine Talouselämä (Economic Life) during the years 2002–2017. Design/methodology/approach A total of 81 articles were included in the analysis. They were classified into seven themes as a result of a content analysis. Three levels of discussions on aging were identified: societal, organizational and individual. T…
“Once an entrepreneur, always an entrepreneur” : positioning analysis of written narratives
2021
PurposeThe negative stereotypes concerning late-career workers are found to prevail and lead to negative circulation of narratives and actions between individuals and societies. Using the context of late-career entrepreneurs, the paper aims to find an alternative and a more positive narrative concerning late-career work by focusing on entrepreneurs and the narrative positioning related to them.Design/methodology/approachThe authors used a narrative-positioning analysis, cycling through three levels of analysis and then returning to level two, in order to study our sample of seven narratives written by Finnish late-career entrepreneurs. The authors present in detail one story-telling narrati…
Effects of a Home‐Based Physical Rehabilitation Program on Tibial Bone Structure, Density, and Strength After Hip Fracture: A Secondary Analysis of a…
2019
Abstract Weight‐bearing physical activity may decrease or prevent bone deterioration after hip fracture. This study investigated the effects of a home‐based physical rehabilitation program on tibial bone traits in older hip fracture patients. A population‐based clinical sample of men and women operated for hip fracture (mean age 80 years, 78% women) was randomly assigned into an intervention (n = 40) and a standard care control group (n = 41) on average 10 weeks postfracture. The intervention group participated in a 12‐month home‐based rehabilitation intervention, including evaluation and modification of environmental hazards, guidance for safe walking, nonpharmacological pain management, m…
Murtumatta mukana - lujuutta liikkumalla : liikuntaryhmiin osallistumisen yhteys ryhmäläisten fyysiseen aktiivisuuteen, fyysiseen toimintakykyyn ja t…
2016
Tarkoitus: Tämän tutkimuksen tarkoituksena oli selvittää, onko Murtumatta mukana – lujuutta liikkumalla – vertaiskoulutettujen ohjaajien ohjaamiin vertaisliikuntaryhmiin osallistumisella yhteyttä ryhmäläisten fyysiseen aktiivisuuteen, fyysiseen toimintakykyyn ja tasapainoon. Menetelmät: Tutkimusasetelma oli havainnoiva poikkileikkausasetelma. Eläkeliiton osoittamat vertaisohjaajat Jyväskylän ja Lapuan alueella tiedottivat tutkimuksesta ja jakoivat kysely-lomakkeita tutkimuksesta kiinnostuneille vertaisliikuntaryhmäläisille. Tutkimuskyselyitä pa-lautui 100 kpl, joista muodostettiin 6kk liikuntaryhmässä mukana olleiden (N=57) ryhmät. Lisäksi vapaaehtoisille halukkaille (N=62) tehtiin tasapain…
Individualized counselling for active aging: protocol of a single-blinded, randomized controlled trial among older people (the AGNES intervention stu…
2019
Background: Active aging has been established as a policy goal for aging societies. We define active aging at the individual level as striving for elements of well-being through activities in relation to a person’s goals, functional capacities and opportunities. Increasing evidence suggests that any meaningful activity is beneficial for different aspects of well-being in older people. The aim of the present randomized controlled trial is to test the feasibility and effectiveness of a one-year community-based intervention on active aging. The AGNES intervention aims at increasing older peoples’ participation in self-selected valued activities. Methods: The proposed study is a two-arm single-…
Effects of a 9-month resistance training intervention on quality of life, sense of coherence, and depressive symptoms in older adults: randomized con…
2017
Purpose (1) To determine the effects of a 9-month resistance training intervention on quality of life, sense of coherence, and depressive symptoms in older adults, and (2) to compare effects between different training frequencies. Methods Men and women aged 65–75 (N = 106) were randomized to four groups according to training frequency: training groups RT1 (n = 26), RT2 (n = 27), and RT3 (n = 28) and non-training control group (n = 25). All training groups attended supervised resistance training twice a week for 3 months. For the following 6 months, they continued training with different frequencies (1, 2 or 3 times per week). Psychological functioning was measured by quality of life (WHOQOL…
The effect of physical activity counseling on diabetics' mobility : results of a secondary analysis
2013
The preservation of mobility is essential for maintaining an independent and active lifestyle in old age. However, diabetes greatly increases older people’s susceptibility to mobility loss, leading to an increased risk of dependence. Given the increased prevalence of diabetes with age, and the increasing incidence of the disease worldwide, public health initiatives for preventing mobility loss with age must also prove effective for diabetics. The screening and counseling for physical activity among older people (SCAMOB) study examines the effectiveness of physical activity counseling for the prevention of mobility loss in an older population. Although the cohort as a whole has shown positiv…
Activity typologies as a design model for the ubiquitous detection of daily routines
2018
Emerging technologies open up new visions and business potential for systems design and development in the areas of wellbeing and health. New technologies enable the detection of human performance and early changes in physical and cognitive functioning, making it possible to monitor an older person’s wellbeing. This kind of technology or service sets significant requirements for design, as design concepts must be able to capture the complexity of people’s daily lives in terms of activities and environments. Technology itself is “blind” unless designers can adapt it to human life. There is thus a distinct need for comprehensive design and development models that generate adequate human requi…