Search results for "ikääntyminen"
showing 10 items of 427 documents
Visual acuity in relation to functional performance, falls and mortality in old age
2010
Mortality associations with DNA methylation-based biological aging and physical functioning measures across a 20-year follow-up period
2023
Background Measures of biological aging range from DNA methylation (DNAm)-based estimates to measures of physical abilities. The purpose of this study was to compare DNAm- and physical functioning-based measures of biological aging in predicting mortality. Methods We studied 63- to 76-year-old women (N = 395) from the Finnish Twin Study on Aging (FITSA). Participants’ biological age (epigenetic clocks DNAm GrimAge and DunedinPACE) was estimated using blood DNAm data. Tests of physical functioning conducted under standardized laboratory conditions included the Timed Up and Go (TUG) test and 10-m walk test. Mortality hazard ratios (HRs) were calculated per every one standard deviation (SD) in…
Does the epigenetic clock GrimAge predict mortality independent of genetic influences : an 18 year follow-up study in older female twin pairs
2021
Background: Epigenetic clocks are based on DNA methylation (DNAm). It has been suggested that these clocks are useable markers of biological aging and premature mortality. Because genetic factors explain variations in both epigenetic aging and mortality, this association could also be explained by shared genetic factors. We investigated the infuence of genetic and lifestyle factors (smoking, alcohol consumption, physical activity, chronic diseases, body mass index) and education on the association of accelerated epigenetic aging with mortality using a longitudinal twin design. Utilizing a publicly available online tool, we calculated the epigenetic age using two epigenetic clocks, Horvath D…
Depressive Symptoms and Mortality : Findings from Helsinki Birth Cohort Study
2023
Background Individuals with depression and depressive symptoms have a higher mortality rate than non-depressed individuals. The increased comorbidity and mortality associated with depression has remained largely unexplained. The underlying pathophysiological differences between depressive subtypes, melancholic and non-melancholic, may provide some explanation to this phenomenon. Methods 1995 participants (mean age 61 years) from the Helsinki Birth Cohort Study were recruited for this prospective study and followed up for a mean of 14.1 years. Information regarding medical history, lifestyle, and biochemical parameters were obtained. Depressive symptoms were assessed using the Beck Depressio…
Job strain among blue-collar and white-collar employees as a determinant of total mortality: a 28-year population-based follow-up.
2012
Objectives To investigate the effect of job demand, job control and job strain on total mortality among white-collar and blue-collar employees working in the public sector. Design 28-year prospective population-based follow-up. Setting Several municipals in Finland. Participants 5731 public sector employees from the Finnish Longitudinal Study on Municipal Employees Study aged 44–58 years at baseline. Outcomes Total mortality from 1981 to 2009 among individuals with complete data on job strain in midlife, categorised according to job demand and job control: high job strain (high job demands and low job control), active job (high job demand and high job control), passive job (low job demand a…
Hermolihasjärjestelmän suorituskyky 40-, 50-, 60-, 75-vuotiailla yleisurheilun veteraaniheittäjillä
2005
Tommi Ojanen. 2005. Hermolihasjärjestelmän suorituskyky 40-, 50-, 60-, 75- vuotiailla yleisurheilunveteraaniheittäjillä. Pro Gradu–tutkielma, Liikuntabiologian laitos. Jyväskylän yliopisto,66 sivua.Tämän tutkimuksen tarkoituksena oli pyrkiä selvittämään aktiivisesti harjoittelevien eri-ikäistenyleisurheilun veteraaniheittäjien voimantuotollisia ominaisuuksia ja samalla kuvaamaan ikääntymisenvaikutuksia hermo-lihasjärjestelmän voimantuottoon. Tutkimukseen osallistui 32 eriikäistä(36 – 85- vuotta) veteraanisarjojen kuulantyönnössä, kiekonheitossa, moukarinheitossa japainonheitossa kilpailevaa mieshenkilöä, joista muodostettiin neljä ikäryhmää; M40 (n=6), M50(n=5), M60 (n=12) ja M75 (n=9). Lis…
"Lauletaan vaan yhdessä, pojat!" : musiikki ja identiteetti sotiemme veteraanien ryhmämusiikkiterapiassa - etnografis-narratiivinen tutkimus
2016
Studies concerning music and identity have shown that the music which an individual values as important tells stories about the subjective reality of the individual (Lehtonen & Niemelä 1997; Baker & Wigram 2004). Through the use of individualized meaningful music in music therapy, a possibility for raising and evaluating processes connected with identity can be created (Magee & Davidson 2004b). Even recent brain studies have shown these connections. When meaningful music is used activity is observed within deep parts of the brain, suggesting a connection between contextualized meaningful music and activity in the brain where the pleasure and the autobiographical memory centers exist (Buruna…
Iästä johtamiseen : ikäjohtaminen ja eri-ikäisyys johtajuuden tutkimuskohteena
2011
Job satisfaction mediates the association between perceived leadership styles and early retirement intentions
2016
The ageing of the population is particularly challenging for the healthcare sector, which is at the same time facing a nursing shortage. Therefore, improving work conditions and well-being at work in order to prolong nurses’ careers and retention in their profession until retirement age has become one of the key issues of healthcare leaders and policymakers. This study tested a structural model linking nurses’ perceived leadership styles and early retirement intentions. We tested the model in a sample of 343 nurses at one Finnish university hospital. It was hypothesized that the relationship between perceived leadership styles and early retirement intentions would be mediated by job satisfa…