Search results for "ikääntyminen"
showing 10 items of 427 documents
Early-Life Factors as Predictors of Age-Associated Deficit Accumulation Across 17 Years From Midlife Into Old Age
2022
Abstract Background Early-life exposures have been associated with the risk of frailty in old age. We investigated whether early-life exposures predict the level and rate of change in a frailty index (FI) from midlife into old age. Methods A linear mixed model analysis was performed using data from 3 measurement occasions over 17 years in participants from the Helsinki Birth Cohort Study (n = 2 000) aged 57–84 years. A 41-item FI was calculated on each occasion. Information on birth size, maternal body mass index (BMI), growth in infancy and childhood, childhood socioeconomic status (SES), and early-life stress (wartime separation from both parents) was obtained from registers and health ca…
Early life determinants of frailty in old age : the Helsinki Birth Cohort Stud
2018
Background there is evidence suggesting that several chronic diseases have their origins in utero and that development taking place during sensitive periods may affect the aging process. We investigated whether early life determinants would be associated with frailty in old age. Methods at a mean age of 71 years, 1,078 participants belonging to the Helsinki Birth Cohort Study were assessed for frailty according to the Fried frailty criteria. Early life measurements (birth weight, length, mother body mass index [BMI] and parity) were obtained from birth, child welfare and school health records. Multinomial regression analysis was used to assess the association between early life determinants…
Personal goals in old age : relationships with resources in life, exercise activity, and life-space mobility
2016
Voimaharjoittelun ja proteiinisupplementaation vaikutus myostatiinin ja siihen liittyvien geenien ilmentymiseen nuorilla ja vanhoilla miehillä
2008
Salmijärvi, Hanna 2008. Voimaharjoittelun ja proteiinisupplementaation vaikutus myostatiinin ja siihen liittyvien geenien ilmentymiseen nuorilla ja vanhoilla miehillä. Liikuntafysiologian Pro gradu – tutkielma. Jyväskylän yliopisto. Liikuntabiologian laitos, 80s. Myostatiini vaikuttaa luurankolihasten kasvuun negatiivisesti pääasiallisesti estämällä satelliittisolujen kypsymistä ja erilaistumista. Hypertrofiaolosuhteissa satelliittisolut jakautuvat ja luovuttavat lihassoluihin uusia tumia. Myogeeniset säätelytekijät MyoD ja myogeniini säätelevät satelliittisolujen kypsymistä ja erilaistumista. Riittävä proteiinien saanti on hypertrofialle välttämätöntä fyysisen suorituksen yhteydessä. Ikään…
Muscle hypertrophy and serum hormone concentrations during combined strength and endurance training vs. strength or endurance training only in middle…
2008
Jensen, Benjamin 2008. Muscle hypertrophy and serum hormone concentrations during combined strength and endurance training vs. strength or endurance training only in middle aged and older women. University of Jyväskylä, Department of Biology of Physical Activity. Master’s thesis in Science of Sport Coaching and Fitness Testing. 70 pp. Purpose: The purpose of this investigation was to compare the effects of strength training only (2 x week), endurance training only (2 x week), and combined training (2 + 2 x week) on muscle hypertrophy and serum hormone concentrations in middle-aged and older women during 21 weeks of training. Methods: 96 healthy, moderately active middle-aged and older women…
Iän vaikutus lihasarkkitehtuuriin 16-85-vuotiailla pikajuoksijoilla
2003
Tämän tutkimuksen tarkoituksena oli selvittää ikääntymisen vaikutusta vastuslateraliksen (VL), gastrocnemius medialiksen (GM) ja gastrocnemius lateraliksen (GL)paksuuteen, lihassyykimppujen pennaatiokulmaan sekä pituuteen. Koehenkilöinä oli 9316-85-vuotiasta miespikajuoksijaa, jotka harrastivat kilpailumielessä pikajuoksuaveteraanisarjoissa. Pennaatiokulmat ja lihaspaksuudet mitattiin yhdestä kohdastalihaksen päältä reaaliaikaisella B-mallin ultraäänilaitteella ja lihassyykimpun pituusarvioitiin pennaatiokulman ja lihaspaksuuden avulla.Korrelaatioanalyysi osoitti sekä absoluuttisen että raajan pituuteen suhteutetun lihaksenpaksuuden vähenevän merkitsevästi kaildssa mitatuissa lihaksissa iän…
Fear of falling and coexisting sensory difficulties as predictors of mobility decline in older women
2012
Background. Mobility decline, the coexistence of several sensory difficulties and fear of falling (FOF) are all common concerns in older people; however, knowledge about the combined effect of FOF and coexisting sensory difficulties on mobility is lacking. Methods. Data on self-reported FOF, difficulties in hearing, vision, balance, and walking 2 km were gathered with a structured questionnaire among 434 women aged 63–76 years at baseline and after a 3-year follow-up. Logistic regression models were used for analyses. Results. Every third participant reported difficulties in walking 2 km at baseline. In cross-sectional analysis, the odds ratio for difficulties in walking 2 km was higher amo…
Promoting mobility after hip fracture (ProMo): study protocol and selected baseline results of a year-long randomized controlled trial among communit…
2011
Background. To cope at their homes, community-dwelling older people surviving a hip fracture need a sufficient amount of functional ability and mobility. There is a lack of evidence on the best practices supporting recovery after hip fracture. The purpose of this article is to describe the design, intervention and demographic baseline results of a study investigating the effects of a rehabilitation program aiming to restore mobility and functional capacity among community-dwelling participants after hip fracture. Methods/Design. Population-based sample of over 60-year-old community-dwelling men and women operated for hip fracture (n = 81, mean age 79 years, 78% were women) participated in t…
Painoindeksin yhteys liikkumiskyvyn palautumiseen iäkkäillä lonkkamurtumapotilailla
2015
Kaatumisen seurauksena syntyvät lonkkamurtumat ovat yleisiä iäkkäillä henkilöillä. Lonkkamurtumat aiheuttavat yksilölle kärsimystä ja yhteiskunnalle mittavia kustannuksia. Lonkkamurtuma saattaa johtaa liikkumiskyvyn rajoitukseen, joka voi olla pitkäaikaista tai pysyvää. Alhainen painoindeksi on lonkkamurtuman merkittävä riskitekijä, kun taas ylipainon tiedetään olevan yhteydessä moniin terveyshaittoihin sekä heikompaan liikkumiskykyyn terveillä kotona asuvilla vanhuksilla. Painoindeksin yhteyttä lonkkamurtuman kokeneiden liikkumiskyvyn palautumisen on aikaisemmin tutkittu niukasti. Tämä tutkimuksen tarkoituksena on selvittää kotona toteutetun kuntoutusintervention vaikutuksia lonkkamurtumas…
Trajectories of mobility limitations over 24 years and their characterization by shift work and leisure-time physical activity in midlife
2019
Background We aimed to investigate trajectories of mobility limitations (MLs) over a period of 24 years. In addition, we aimed to study how shift work and leisure-time physical activity (LTPA) in midlife predict assignment to MLs trajectories separately for those retired on statutory pensions (SPs) and on disability pensions (DPs). Methods Subjects who responded MLs questionnaires (1985–2009, N = 3048) in Finnish Longitudinal Study on Aging Municipal Employees were included in this prospective cohort study. LTPA and shift work were measured during baseline. International Classification of Functioning was used to code MLs. Growth mixture modeling was used to identify the trajectories of MLs.…