Search results for "illness"

2007

Anderson-Fabry Disease: A Multiorgan Disease

2013

Fabry disease (FD) is a rare X-linked lysosomal storage disorder caused by a deficiency of the enzyme α-galactosidase A . FD causes glycolipids, such as globotriaosylceramide (Gb3), to accumulate in the vascular endothelium of several organs (fig.2), including the skin, kidneys, nervous system, and heart, thereby triggering inflammation and fibrosis . These processes generally result in organ dysfunction, which is usually the first clinical evidence of FD. Patients with classic FD have various symptoms, eg, acroparesthesias, hypohidrosis, angiokeratomas, corneal opacities, cerebrovascular lesions, cardiac disorders, andrenal dysfunction.However, evolving knowledge about the natural course o…

Exacerbated experimental autoimmune encephalomyelitis in mast-cell-deficient KitW-sh/W-sh mice

2011

Mast cell (MC)-deficient c-Kit mutant Kit(W/W-v) mice are protected against experimental autoimmune encephalomyelitis (EAE), an animal model of multiple sclerosis, suggesting a detrimental role for MCs in this disease. To further investigate the role of MCs in EAE, we took advantage of a recently characterized model of MC deficiency, Kit(W-sh/W-sh). Surprisingly, we observed that myelin oligodendrocyte glycoprotein (MOG)(35-55)-induced chronic EAE was exacerbated in Kit(W-sh/W-sh) compared with Kit(+/+) mice. Kit(W-sh/W-sh) mice showed more inflammatory foci in the central nervous system (CNS) and increased T-cell response against myelin. To understand whether the discrepant results obtaine…

Cancer care for the homeless population: a literature review

2020

Abstract Background The last global survey in 2005 of the United Nations estimated that 100 million people were homeless. Cancer is becoming one of the most important public health problems worldwide, but specifically, the prevalence of cancer-related mortality for the homeless population has been reported to be double compared to the average adult population. To date, health research pays insufficient attention to studying cancer and improving the delivery of cancer care for the homeless population. Methods A systematic literature review of relevant databases was employed to identify all the quantitative studies addressing cancer care for the homeless population in English, Spanish, French…

Prevalence, correlates, and predictors of depersonalization experiences in the German general population.

2009

The survey aimed to investigate the prevalence of depersonalization (DP) experiences, its sociodemographic characteristics and its associations with medical conditions, illness behavior, and potential etiologic factors. A representative face-to-face household survey was conducted. The sample consists of n = 1,287 participants aged 14 to 90 years. Sociodemographic variables, medical conditions, current mental disorders, health care utilization, and childhood adversities were assessed. A total of 1.9% participants scored in the range of clinically significant DP (DP-C) and 9.7% reported at least some impairment through DP (DP-I). DP-C/DP-I were strongly associated with depression and anxiety.…

Psychological defense styles, childhood adversities and psychopathology in adulthood.

2003

OBJECTIVE: The present study explores the link between reported sexual and/or physical abuse and psychological defense styles, as well as the association of both with psychological distress in adulthood. In two patient samples that differ in psychological distress and somatization, we examine whether the adversities reported and immature defense styles are associated with psychopathological symptoms. METHOD: We examined 266 consecutive inpatients in the psychosomatic department and 109 consecutive inpatients who had been treated for low-back pain in the orthopedic department of a German university hospital. Psychological defense styles were assessed by a two-factor solution of the German mo…

The Meaning of Food in the Novel "Peony in Love"

2018

The aim of the paper is to show universal and culture-specific meanings of food, taking into consideration different roles nutrition plays in human life. The complicated nature of relations between people and their meals is illustrated with examples from literature, based on the book Peony in Love by Asian American contemporary author Lisa See. The book makes a good example of the subject of food and culture as the main plot is connected with traditional Chinese opera that influenced young women to die of starvation because of love sickness. The Peony Pavilion (Chinese: 牡丹亭; pinyin: Mǔdān tíng) is a play written by Tang Xianzu in the Ming Dynasty and first performed in 1598, but its message…

Istota odpowiedzialności rodziny za osobę chorą

2020

Opieka nad chorymi jest przedmiotem licznych studiów i opracowań, a w obszarze teologii moralnej wiąże się głównie z problematyką odpowiedzialności różnych podmiotów, w tym samego chorego, za proces leczenia i podejście do osób wymagających troski. Jednym z tych podmiotów jest najbliższe otoczenie osoby chorej, które stanowi rodzina. Niniejszy artykuł przedstawia problem istoty odpowiedzialności za osobę chorą, która spoczywa na rodzinie. Na początku autor prezentuje zjawisko choroby i jej wielorakie odniesienia do życia rodziny. Następnie zostało omówione znaczenie rodziny w doświadczeniu choroby. Po wyjaśnieniu doświadczeń choroby w rodzinie został przedstawiony problem istoty odpowiedzia…

Critical single proximal left arterial descending coronary artery stenosis to mimic chronic myocardial ischemia: a new model induced by minimal invas…

2008

<i>Background/Aims:</i> The present report examines a new pig model for progressive induction of high-grade stenosis, for the study of chronic myocardial ischemia and the dynamics of collateral vessel growth. <i>Methods:</i> Thirty-nine Landrace pigs were instrumented with a novel experimental stent (GVD stent) in the left anterior descending coronary artery. Eight animals underwent transthoracic echocardiography at rest and under low-dose dobutamine. Seven animals were examined by nuclear PET and SPECT analysis. Epi-, mid- and endocardial fibrosis and the numbers of arterial vessels were examined by histology. <i>Results:</i> Functional analysis showed a…

Concensus Rorschach interaction patterns of families with an asthmatic child

1987

This paper reports a study of interaction in families with a child suffering from bronchial asthma. Eighteen families, subdivided into two groups according to the severity of the child's illness, were given the Consensus Rorschach following Willi's procedure. Quantitative assessments of family members on cognitive-affective functioning and social interaction were obtained. Factor analysis of quantitative scores revealed diversified interactional strategies among family member groups. Families as wholes varied as to patterns of cross-generational alliances and/or domination of different family members and could be clustered into four interactional pattern groups. There was no correlation bet…