Search results for "illness"

showing 10 items of 1529 documents

Prophylaxis In Congenital Factor VII Deficiency, Indications, Efficacy and Safety: Results of the STER

2010

Abstract Abstract 665 Introduction Prophylaxis is considered a difficult endeavour in FVII deficiency, especially because of the very short FVII zymogen and FVIIa half-lives, mainly in childhood. The Seven Treatment Evaluation Registry (STER, www.targetseven.org) is a prospective observational, multi-centre, web-based registry concerned with the evaluation of treatments for spontaneous bleeding episodes, surgery and prophylaxis in patients with FVII deficiency. As regards prophylaxis, STER provides the frame for a structured and detailed data capture aiming at: a) identifying patients in whom prophylaxis is advisable, b) defining clinical settings in which prophylaxis is necessary and c) de…

Gastrointestinal bleedingPediatricsmedicine.medical_specialtybusiness.industryImmunologyCell BiologyHematologyHemarthrosismedicine.diseaseBiochemistryRegimenConcomitantSeverity of illnessmedicineProphylaxis in Factor VII deficiency inherited Factor VII deficiencyObservational studyDosingFresh frozen plasmabusinessBlood
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Thresholds of hope: stories of lacking generosity

2019

ABSTRACTHope is a pivotal part of recovery in a broad range of health conditions, including those relating to the field of mental health and substance abuse. People who experience co-occurring ment...

GenerosityAddictionmedia_common.quotation_subject05 social sciencesPublic Health Environmental and Occupational Healthmedicine.diseaseMental illnessMental health030227 psychiatryDevelopmental psychologySubstance abuse03 medical and health sciences0302 clinical medicinemedicineDual diagnosis0501 psychology and cognitive sciencesPsychologySocial Sciences (miscellaneous)050104 developmental & child psychologymedia_commonSocial Work in Mental Health
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Factors influencing psychological well-being in patients with Parkinson's disease.

2017

Background Both motor and non-motor symptoms could contribute to significant deterioration of psychological well-being in patients with Parkinson's disease (PD). However, its assessment has been only indirectly evaluated using tools based on health-related quality of life (HRQoL), such as the PDQ-39 scale. Objectives To evaluate psychological well-being in PD using a specific tool of assessment, the Psychological Well-being Scale (PWS), and its clinical correlates. Methods This article reports data of patients' perception of health state, as measured by means of the PWS, from an epidemiological, cross-sectional study conducted in Italian PD patients (FORTE Study). We tested possible relatio…

Genetics and Molecular Biology (all)MaleParkinson's diseaseEmotionsPoison controlSocial Scienceslcsh:MedicinePathology and Laboratory MedicineBiochemistrySeverity of Illness IndexAged; Depression; Fatigue; Female; Humans; Italy; Male; Middle Aged; Parkinson Disease; Psychiatric Status Rating Scales; Quality of Life; Severity of Illness Index; Surveys and Questionnaires; Biochemistry Genetics and Molecular Biology (all); Agricultural and Biological Sciences (all)0302 clinical medicineMathematical and Statistical TechniquesQuality of lifeSurveys and QuestionnairesMedicine and Health SciencesMedicinePsychologySurveys and Questionnaire030212 general & internal medicinelcsh:ScienceDepression (differential diagnoses)FatigueMultidisciplinaryMovement DisordersDepressionNeurodegenerative DiseasesParkinson DiseaseMiddle AgedPsychiatric Status Rating ScalehumanitiesNeurologyItalyPhysical SciencesFemaleStatistics (Mathematics)Clinical psychologyResearch ArticleHumanResearch and Analysis Methods03 medical and health sciencesSigns and SymptomsDiagnostic MedicineSeverity of illnessInjury preventionMental Health and PsychiatryHumansStatistical MethodsAgedPsychiatric Status Rating Scalesparkinson's disease quality of lifeAnalysis of VarianceBiochemistry Genetics and Molecular Biology (all)business.industryMood Disorderslcsh:RBeck Depression InventoryBiology and Life Sciencesmedicine.diseaseHealth CareAgricultural and Biological Sciences (all)Psychological well-beingAged; Depression; Fatigue; Female; Humans; Italy; Male; Middle Aged; Parkinson Disease; Psychiatric Status Rating Scales; Quality of Life; Severity of Illness Index; Surveys and QuestionnairesQuality of Lifelcsh:QbusinessSleep Disorders030217 neurology & neurosurgeryMathematicsPLoS ONE
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A framework for remission in SLE

2017

ObjectivesTreat-to-target recommendations have identified ‘remission’ as a target in systemic lupus erythematosus (SLE), but recognise that there is no universally accepted definition for this. Therefore, we initiated a process to achieve consensus on potential definitions for remission in SLE.MethodsAn international task force of 60 specialists and patient representatives participated in preparatory exercises, a face-to-face meeting and follow-up electronic voting. The level for agreement was set at 90%.ResultsThe task force agreed on eight key statements regarding remission in SLE and three principles to guide the further development of remission definitions:1. Definitions of remission wi…

Genetics and Molecular Biology (all)PediatricsAutoimmune diseasesNEPHRITIS PATIENTSDISEASE-ACTIVITYSeverity of Illness IndexBiochemistryRETROSPECTIVE ANALYSIS0302 clinical medicineQuality of lifePrednisoneAdrenal Cortex HormonesLupus Erythematosus SystemicImmunology and AllergyCHINESE PATIENTS030212 general & internal medicineSYSTEMIC-LUPUS-ERYTHEMATOSUSskin and connective tissue diseasesPREDICTORSOUTCOMESSystemic lupus erythematosusMalalties autoimmunitàriesRemission InductionSYSTEMIC-LUPUS-ERYTHEMATOSUS; DISEASE-ACTIVITY; RETROSPECTIVE ANALYSIS; INITIAL VALIDATION; NEPHRITIS PATIENTS; AMERICAN-COLLEGE; CHINESE PATIENTS; RENAL FLARES; PREDICTORS; OUTCOMESSymptom Flare UpConnective tissue diseaseManchester Institute for Collaborative Research on AgeingEstudi de casosOutcomes researchAntibodies AntinuclearDNA/immunologyImmunosuppressive Agentsmedicine.drugmedicine.medical_specialtyFarmacologiaResearchInstitutes_Networks_Beacons/MICRAConsensusImmunologyAdrenal Cortex Hormones/therapeutic useAMERICAN-COLLEGELupus Erythematosus Systemic/bloodSystemic Lupus ErythematosusGeneral Biochemistry Genetics and Molecular BiologyMaintenance Chemotherapy03 medical and health sciencesAntimalarialsRheumatologySeverity of illnessmedicineDisease Activity; Outcomes research; Systemic Lupus Erythematosus; Immunology and Allergy; Rheumatology; Immunology; Biochemistry Genetics and Molecular Biology (all)HumansDisease Activity030203 arthritis & rheumatologyPharmacologyAntibodies Antinuclear/bloodLupus erythematosusbusiness.industryTask forceConstruct validityRENAL FLARESComplement System ProteinsDNAINITIAL VALIDATIONDisease Activity; Outcomes research; Systemic Lupus Erythematosusmedicine.diseaseLupus eritematósAntimalarials/therapeutic usePhysical therapyImmunosuppressive Agents/therapeutic useComplement System Proteins/metabolismCase studiesOutcomes researchbusinessAnnals of the Rheumatic Diseases
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Caring, employment, and quality of life: comparison of employed and nonemployed mothers of adults with intellectual disability.

2010

Abstract The effects of caregiving on mothers of adults with intellectual disability was examined by determining whether there are differences in quality of life and related factors between mothers with different employment status. Study participants were 302 working-age mothers who had adult children with intellectual disability based on the 2008 census survey on intellectual disability carried out in Hsinchu, City, Taiwan. Results revealed that nonemployed mothers are more likely to have a lower level of health status, including the WHOQOL Physical Health domain, than are mothers employed fulltime. Multiple regression analysis showed that mothers' quality of life was significantly determi…

GerontologyAdultEmploymentMalemedicine.medical_specialtyHealth StatusTaiwanMothersFamily incomeDevelopmental psychologySocial supportQuality of life (healthcare)Arts and Humanities (miscellaneous)Cost of IllnessIntellectual disabilityActivities of Daily LivingDevelopmental and Educational PsychologymedicineHumansChild rearingPublic healthSocial environmentSocial SupportGeneral MedicineMiddle Agedmedicine.diseaseMental healthPsychiatry and Mental healthNeuropsychology and Physiological PsychologyCaregiversPediatrics Perinatology and Child HealthIncomeQuality of LifeAdult ChildrenFemaleNeurology (clinical)PsychologyRespite CareAmerican journal on intellectual and developmental disabilities
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Life expectancy of people with intellectual disability: a 35-year follow-up study.

2000

A 35-year follow-up study based on a nation-wide population study of the life expectancy of people with intellectual disability (ID) was undertaken. The study population consisted of a total of 60,969 person-years. A prospective cohort study with mortality follow-up for 35 years was used and the life expectancy of people with ID was calculated for different levels of intelligence. Proportional hazard models were used to assess the influence of level of intelligence and associated disorders on survival. People with mild ID did not have poorer life expectancy than the general population and subjects with mild ID did not have lower life expectancy in the first 3 decades of life. In cases with …

GerontologyAdultMale030506 rehabilitationAdolescentHealth StatusPopulationSeverity of Illness Index03 medical and health sciences0302 clinical medicineLife ExpectancySex FactorsArts and Humanities (miscellaneous)Risk FactorsIntellectual DisabilityHealth careIntellectual disabilitySeverity of illnessmedicineHumans030212 general & internal medicine10. No inequalityeducationProspective cohort studyChildAgedAged 80 and overeducation.field_of_studybusiness.industryRehabilitationMiddle Agedmedicine.disease3. Good healthPsychiatry and Mental healthNeurologyRelative riskChild PreschoolLife expectancyPopulation studyFemaleNeurology (clinical)0305 other medical sciencebusinessPsychologyDemographyFollow-Up StudiesJournal of intellectual disability research : JIDR
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Resilience in Informal Caregivers of People Living with Dementia in the Face of COVID-19 Pandemic-Related Changes to Daily Life

2022

Abstract. Informal caregivers of people living with dementia (PwD) are at increased risk for the development of stress-related physical and mental illness. Nevertheless, because of differing resilience, they show interindividual differences in their ability to cope. Particularly during the COVID-19 pandemic, with the associated pandemic control measures and pandemic-related changes to daily life, resilience might be further challenged, and stress might consequently increase. Therefore, we review the evidence on informal caregivers’ experience during the COVID-19 pandemic regarding effects of the pandemic control measures on (a) the caregiver’s health, (b) the care recipient’s health, (c) th…

GerontologyCoronavirus disease 2019 (COVID-19)media_common.quotation_subjectSocial distanceFace (sociological concept)Caregiver burdenmedicine.diseaseMental illnessPandemicmedicineDementiaPsychological resilienceGeriatrics and GerontologyPsychologyGerontologymedia_commonGeroPsych
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Adverse Clinical Events and Mortality During Hospitalization and 3 Months After Discharge in Cognitively Impaired Elderly Patients

2012

BACKGROUND: Controversial findings are reported on hospital outcome in cognitively impaired patients. The aim of this study was to explore mortality risk according to cognitive status during hospitalization and after 3 months in elderly patients. METHODS: Sixty-six internal medicine and geriatric wards in Italy participated in the "Registry Politerapie SIMI (REPOSI)" during 2010. Of the 1,380 in-patients, aged 65 and older enrolled, 1,201 were included. Cognition was evaluated with the Short Blessed Test (SBT). Logistic regression was used to evaluate the association of questionable and impaired cognition (according to SBT cutoff points) with mortality during hospitalization and at follow-u…

GerontologyMaleARDSTime FactorsSettore MED/09 - Medicina InternaActivities of Daily Living Aged Aged; 80 and over Cognition Disorders; diagnosis/mortality Female Geriatric Assessment; methods Hospital Mortality Hospitalization; statistics /&/ numerical data Humans Intelligence Tests Italy; epidemiology Logistic Models Male Odds Ratio Patient Discharge; statistics /&/ numerical data Risk Assessment; methods Risk Factors Severity of Illness Index Time Factorsdiagnosis/mortalitycognitively impaired patients; Registry Politerapie SIMI (REPOSI); Elderly patients;Logistic regressionSeverity of Illness IndexDementia; agingRisk FactorsActivities of Daily Living80 and overOdds RatioHospital MortalityAged 80 and overIntelligence TestsAdverse clinical eventsCognitionSettore MED/45 - Scienze Infermieristiche Generali Cliniche E PediatrichePatient Dischargestatistics /&/ numerical dataHospitalizationItalyFemaleepidemiologyElderly patientmedicine.medical_specialtyelderly patientsRisk AssessmentOddsmethodsNOInternal medicinemedicineDementiaHumansRegistry Politerapie SIMI (REPOSI)Adverse effectGeriatric Assessmentcognitive functionAgedbusiness.industryagingOdds ratiocognitively impaired patientmedicine.diseasemortalityConfidence intervalhospital admissionLogistic ModelsAdverse clinical events; elderly patients; cognitive function; mortality; hospital admissionDementiaGeriatrics and GerontologybusinessCognition Disorders
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Physical Activity Among Adolescents With Long-Term Illnesses or Disabilities in 15 European Countries.

2017

Physical activity (PA) is an important health-promoting behavior from which adolescents with long-term illnesses or disabilities (LTID) can benefit. It is important to monitor differences across countries in adherence with PA recommendations for health. The aim of this study was to compare PA levels among 15 European countries after disaggregating data by disability. Data from pupils (mean age = 13.6 years, SD = 1.64) participating in the 2013/2014 Health Behavior in School-aged Children study were analyzed to compare adolescents without LTID, with LTID, and with LTID that affects their participation (affected LTID). Logistic regression models adjusted for age and family affluence, stratifi…

GerontologyMaleChronic conditionsmedicine.medical_specialtyAdolescentvammaisetPhysical activityphysical activityPhysical Therapy Sports Therapy and RehabilitationliikuntaLogistic regression03 medical and health sciences0302 clinical medicineOutcome variablenuoretMainstream schoolsSDG 3 - Good Health and Well-beingRA0421RA0421 Public health. Hygiene. Preventive MedicineCountry grouplong-term IllnessesMedicineHumanstoimintarajoitteetDisabled Personsadolescents030212 general & internal medicineEurooppakrooniset tauditPsychiatryChildExerciseInclusionDisability030505 public healthbusiness.industry3rd-DASEuropeHealthChronic DiseaseFemaleSelf ReportHealth behavior0305 other medical sciencebusinessterveysInclusion (education)fyysinen aktiivisuusAdapted physical activity quarterly : APAQ
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Social economic costs and health-related quality of life in patients with amyotrophic lateral sclerosis in Spain.

2008

Amyotrophic lateral sclerosis (ALS) is a process that leads to the functional disability of the individual in a relatively short period of time, with a very important limitation of autonomy and affecting the quality of life. We wished to determine the economic burden (direct and indirect costs), as well as health-related quality of life (HRQoL) in patients with ALS in Spain. A cross-sectional study was carried out on 63 patients with ALS during 2004. A retrospective assessment of the use of resources was obtained through questionnaires completed by the patients and/or the patients' caregivers. The approach used was a cost-of-illness study based on a societal perspective. We assessed the HRQ…

GerontologyMaleCross-sectional studyMEDLINESeverity of Illness IndexIndirect costsQuality of lifeCost of IllnessEconomic costSurveys and QuestionnairesSeverity of illnessMedicineHumansAmyotrophic lateral sclerosisAgedRetrospective Studiesbusiness.industryAmyotrophic Lateral SclerosisRetrospective cohort studyGeneral MedicineHealth Care CostsMiddle Agedmedicine.diseaseCross-Sectional StudiesNeurologyCaregiversSocioeconomic FactorsSpainQuality of LifeFemaleNeurology (clinical)businessAmyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases
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