Search results for "illness"

showing 10 items of 1529 documents

Progression From Paroxysmal to Persistent Atrial Fibrillation. Clinical Correlates and Prognosis

2010

Objectives: We investigated clinical correlates of atrial fibrillation (AF) progression and evaluated the prognosis of patients demonstrating AF progression in a large population. Background: Progression of paroxysmal AF to more sustained forms is frequently seen. However, not all patients will progress to persistent AF. Methods: We included 1,219 patients with paroxysmal AF who participated in the Euro Heart Survey on AF and had a known rhythm status at follow-up. Patients who experienced AF progression after 1 year of follow-up were identified. Results: Progression of AF occurred in 178 (15%) patients. Multivariate analysis showed that heart failure, age, previous transient ischemic attac…

MaleTime FactorPrognosiRisk FactorpredictionMiddle AgedRisk AssessmentSeverity of Illness IndexAtrial FibrillationDisease ProgressionepidemiologyFemaleatrial fibrillation; epidemiology; prediction; prognosis; progression; Aged; Atrial Fibrillation; Female; Humans; Male; Middle Aged; Prognosis; Risk Assessment; Risk Factors; Severity of Illness Index; Time Factors; Disease ProgressionprogressionAgedHuman
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Intensive care unit strain should not rush physicians into making inappropriate decisions, but merely reduce the time to the right decisions being ma…

2016

The effect of capacity strain in an ICU on the timing of end-of-life decision-making is unknown. We sought to determine how changes in strain impact timing of new do-not-resuscitate (DNR) orders and of death.Retrospective cohort study of 9891 patients dying in the hospital following an ICU stay ≥72 h in Project IMPACT, 2001-2008. We examined the effect of ICU capacity strain (measured by standardized census, proportion of new admissions, and average patient acuity) on time to initiation of DNR orders and time to death for all ICU decedents using fixed-effects linear regression.Increases in strain were associated with shorter time to DNR for patients with limitations in therapy (predicted ti…

MaleTime FactorsDatabases Factualcommunication strategySeverity of Illness Indexlaw.invention0302 clinical medicinelawicuVasoconstrictor Agents030212 general & internal medicineHospital MortalityComputingMilieux_MISCELLANEOUSmedia_commonResuscitation OrdersAged 80 and overTerminal CaresupportGeneral MedicineMiddle AgedIntensive care unit3. Good healthIntensive Care UnitsEditorialqualityFemaleMedical emergencyof-life practicesAutonomyAdultmedicine.medical_specialtymedia_common.quotation_subjectCritical IllnessDecision Making03 medical and health sciencesQuality of life (healthcare)[ SDV.MHEP ] Life Sciences [q-bio]/Human health and pathologymedicineendHumansQuality (business)surrogateIntensive care medicineAgedRetrospective Studiescapacity strainbusiness.industry030208 emergency & critical care medicinefamily membersLength of Staymedicine.diseaseRespiration ArtificialcultureLinear Modelsbusiness[SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
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Prevalence of fatigue in Parkinson disease and its clinical correlates

2014

Objective: To assess in a noninterventional setting the prevalence and severity of fatigue in patients with Parkinson disease (PD). Methods: This was a cross-sectional study conducted in Italian patients with PD. Objectives included the evaluation of the current prevalence and severity of fatigue in patients with PD measured using the 16-item Parkinson Fatigue Scale (PFS-16), distressing fatigue (defined as a PFS-16 mean score $3.3), and assessment of its clinical correlates. Results: A total of 402 patients were enrolled and 394 patients completed the PFS-16 questionnaire with a PFS-16 mean (6SD) score of 2.87 6 0.99. Of these, 136 patients (33.8%) reported distressing fatigue (PFS-16 mean…

MaleTime FactorsDiseaseDSM-IV 5 Diagnostic and Statistical Manual of Mental Disorders 4th edition; ICD-10 5 International Classification of Diseases 10th revision; MAO-B 5 monoamine oxidase B; MS 5 multiple sclerosis; PD 5 Parkinson disease; PDQ-39 5 39-item Parkinson’s Disease Questionnaire; PDSS 5 Parkinson’s Disease Sleep Scale; PFS-16 5 16-item Parkinson Fatigue Scale; UPDRS 5 Unified Parkinson’s Disease Rating ScaleSeverity of Illness IndexQuality of life80 and overPrevalencePDSS 5 Parkinson’s Disease Sleep ScaleAge FactorDepression (differential diagnoses)FatigueAged 80 and overDepressionmusculoskeletal neural and ocular physiologyAge FactorsParkinson DiseasePDQ-39 5 39-item Parkinson’s Disease QuestionnaireMiddle AgedItalyPFS-16 5 16-item Parkinson Fatigue ScaleFemaleSettore MED/26 - NeurologiaMS 5 multiple sclerosiPsychologyHumanAdultSleep Wake Disordersmedicine.medical_specialtyPD 5 Parkinson diseasemacromolecular substancesArts and Humanities (miscellaneous)Internal medicinemedicineDistressingHumansIn patientAgedCross-Sectional StudieMAO-B 5 monoamine oxidase BUPDRS 5 Unified Parkinson’s Disease Rating Scalenervous system diseasesAdult; Age Factors; Aged; Aged 80 and over; Cross-Sectional Studies; Depression; Fatigue; Female; Humans; Italy; Male; Middle Aged; Parkinson Disease; Prevalence; Severity of Illness Index; Sleep Wake Disorders; Time Factors; Neurology (clinical); Arts and Humanities (miscellaneous)Cross-Sectional Studiesnervous systemICD-10 5 International Classification of Diseases 10th revisionPhysical therapyNeurology (clinical)DSM-IV 5 Diagnostic and Statistical Manual of Mental Disorders 4th editionSleep Disorder
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Papillary muscle relocation in conjunction with valve annuloplasty improve repair results in severe ischemic mitral regurgitation

2012

OBJECTIVE: The incidence of recurrent mitral regurgitation (MR) after restrictive annuloplasty (RA) was 5% to 20% in several reports. There are many opinions in favor of adding subvalvular procedures to RA to reduce the tenting forces and improve the repair results. METHODS: From March 2003 to May 2010, 55 patients with severe ischemic MR who had undergone papillary muscle (PPM) relocation in conjunction with mitral annuloplasty in our institutions were enrolled. The patients were matched 1:1 with those who underwent isolated RA using the propensity score. The mean left ventricular ejection fraction was 42% ± 6%. The mean tenting area and coaptation depth was 3.2 ± 0.6 cm(2) and 1.3 ± 0.2 c…

MaleTime FactorsMitral Valve AnnuloplastyLeftMyocardial IschemiaKaplan-Meier EstimateSeverity of Illness IndexVentricular Function LeftPapillary muscle annuloplasty mitral regurgitationPostoperative ComplicationsRisk FactorsMitral valve annuloplastyAged; Chi-Square Distribution; Disease-Free Survival; Female; Hospital Mortality; Humans; Italy; Kaplan-Meier Estimate; Logistic Models; Male; Matched-Pair Analysis; Middle Aged; Mitral Valve Insufficiency; Myocardial Ischemia; Papillary Muscles; Postoperative Complications; Propensity Score; Proportional Hazards Models; Risk Assessment; Risk Factors; Secondary Prevention; Severity of Illness Index; Stroke Volume; Time Factors; Treatment Outcome; Ventricular Function Left; Mitral Valve AnnuloplastySecondary PreventionClinical endpointVentricular FunctionHospital MortalityMyocardial infarctionEjection fractionIncidence (epidemiology)Mitral Valve InsufficiencyMiddle AgedPapillary MusclesTreatment Outcomemedicine.anatomical_structureItalyCardiologyFemaleCardiology and Cardiovascular MedicinePulmonary and Respiratory Medicinemedicine.medical_specialtyMatched-Pair AnalysisRisk AssessmentDisease-Free SurvivalInternal medicinemedicineHumansPropensity ScorePapillary muscleAgedProportional Hazards ModelsMitral regurgitationChi-Square Distributionbusiness.industryStroke VolumeSettore MED/23 - Chirurgia Cardiacamedicine.diseaseSurgeryLogistic ModelsPropensity score matchingSurgerybusiness
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Changes in myocardial iron content following administration of intravenous iron (Myocardial‐IRON): Study design

2018

Treatment with intravenous ferric carboxymaltose (FCM) has been shown to improve symptoms, functional capacity, and quality of life in patients with heart failure and iron deficiency. However, the underlying mechanisms for these beneficial effects remain undetermined. The aim of this study is to quantify cardiac magnetic resonance changes in myocardial iron content after administration of intravenous FCM in patients with heart failure and iron deficiency and contrast them with parameters of heart failure severity. This is a multicenter, double-blind, randomized study. Fifty patients with stable symptomatic heart failure, left ventricular ejection fraction <50%, and iron deficiency will be r…

MaleTime FactorsMyocardial ironheart failure030204 cardiovascular system & hematologyFerric CompoundsSeverity of Illness IndexVentricular Function Left030218 nuclear medicine & medical imaginglaw.invention0302 clinical medicineiron deficiencyClinical ProtocolsQuality of lifeRandomized controlled triallawCardiac Magnetic Resonance Ferric Carboxymaltose Heart Failure Iron Deficiency Myocardial IronInfusions IntravenousEjection fractionAnemia Iron-DeficiencyGeneral MedicineIron deficiencyferric carboxymaltoseTreatment OutcomeResearch DesignCardiologyFemaleCardiology and Cardiovascular MedicineCardiac function curvemedicine.medical_specialtyTrial DesignsMagnetic Resonance Imaging CinePlacebocardiac magnetic resonance03 medical and health sciencesDouble-Blind MethodInternal medicinemedicineHumansMaltosemyocardial ironAgedHeart Failurebusiness.industryMyocardiumStroke VolumeRecovery of Functionmedicine.diseaseSpainHeart failureHematinicsQuality of Lifebusiness
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The impact of frailty on ICU and 30-day mortality and the level of care in very elderly patients (≥ 80 years)

2017

Purpose: Very old critical ill patients are a rapid expanding group in the ICU. Indications for admission, triage criteria and level of care are frequently discussed for such patients. However, most relevant outcome studies in this group frequently find an increased mortality and a reduced quality of life in survivors. The main objective was to study the impact of frailty compared with other variables with regards to short-term outcome in the very old ICU population. Methods: A transnational prospective cohort study from October 2016 to May 2017 with 30 days follow-up was set up by the European Society of Intensive Care Medicine. In total 311 ICUs from 21 European countries participated. Th…

MaleTime FactorsOutcome AssessmentFrail Elderly/statistics & numerical data[SDV]Life Sciences [q-bio]HSJ UCIPassiveCritical Care and Intensive Care MedicineFrailty/classification/diagnosis/mortality/therapySeverity of Illness IndexSeverity of illneElderly0302 clinical medicineQuality of lifeElderly; Frailty; ICU; Mortality; Octogenarians; Severity of illness; Aged 80 and over; Critical Illness; Europe; Euthanasia Passive; Female; Frail Elderly; Frailty; Geriatric Assessment; Humans; Intensive Care Units; Length of Stay; Male; Outcome Assessment Health Care; Proportional Hazards Models; Prospective Studies; Quality of Life; Severity of Illness Index; Time Factors; Hospital MortalityOutcome Assessment Health Care80 and overProspective StudiesHospital Mortality030212 general & internal medicineProspective cohort studyAged 80 and overeducation.field_of_studyddc:617FrailtyMortality rate[SDV] Life Sciences [q-bio]EuropeIntensive Care UnitsLength of Stay/statistics & numerical dataCohortIntensive Care Units/statistics & numerical dataCritical IllneFemaleSOFA scoreHumanmedicine.medical_specialtyOctogenariansTime FactorCritical IllnessFrail ElderlyIntensive Care UnitPopulationINTENSIVE-CARESeverity of illnessEurope/epidemiologyOutcome Assessment (Health Care)03 medical and health sciencesOctogenarianIntensive careSeverity of illnessJournal ArticlemedicineHumansCOHORTMortalityOctogenarinansIntensive care medicineeducationGeriatric AssessmentAgedProportional Hazards ModelsOLDEREuthanasiabusiness.industry030208 emergency & critical care medicineLength of StayEuthanasia PassiveHealth CareProspective StudieCritical Illness/mortalityUNITICUEmergency medicineProportional Hazards ModelQuality of LifebusinessIntensive Care Medicine
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Sleep apnea risk in subjects with asthma with or without comorbid rhinitis

2014

BACKGROUND: As many as 80% of patients with asthma suffer from allergic rhinitis (AR), and rhinitis symptoms are associated with sleep complaints The aim of this cross-sectional study was to assess the prevalence of obstructive sleep apnea syndrome risk in patients with asthma and to explore the association between comorbid rhinitis and obstructive sleep apnea syndrome risk. METHODS: Subjects with asthma were recruited by general practitioners during a control visit. Physicians compiled a questionnaire that assessed the presence of AR according to ARIA (Allergic Rhinitis and Its Impact on Asthma) guidelines and factors influencing the risk of obstructive sleep apnea syndrome (gastroesophage…

MaleTime FactorsSettore MED/10 - Malattie dell'Apparato RespiratorioComorbidityCritical Care and Intensive Care MedicineSeverity of Illness IndexRisk FactorsSurveys and QuestionnairesPrevalenceSurveys and QuestionnaireRhinitisriskSleep Apnea ObstructiveMedicine (all)ApneaSleep apneaGeneral MedicineMiddle Agedsleep apneaFemalemedicine.symptomAllergic rhinitis; Asthma; Obstructive sleep apnea syndrome; Risk; Sleep apnea; STOP-BANG; Pulmonary and Respiratory Medicine; Critical Care and Intensive Care MedicineHumanPulmonary and Respiratory MedicineAdultmedicine.medical_specialtyTime Factorobstructive sleep apnea syndromeAllergicInternal medicineSTOP-BANGSeverity of illnessmedicineAllergic rhinitiHumansAsthmaCross-Sectional Studieallergic rhinitisbusiness.industryObstructiveRisk FactorSTOP-BANG; allergic rhinitis; asthma; obstructive sleep apnea syndrome; risk; sleep apneaOdds ratioasthmamedicine.diseaseObesityComorbidityRhinitis Allergicrespiratory tract diseasesObstructive sleep apneaAllergic rhinitis; Asthma; Obstructive sleep apnea syndrome; Risk; Sleep apnea; STOP-BANG; Adult; Asthma; Comorbidity; Cross-Sectional Studies; Female; Humans; Male; Middle Aged; Prevalence; Rhinitis Allergic; Risk Factors; Severity of Illness Index; Sleep Apnea Obstructive; Surveys and Questionnaires; Time FactorsCross-Sectional StudiesPhysical therapybusiness
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Use of Solovov-Badenoch principle in treating severe and recurrent vesico-urethral anastomosis stricture after radical retropubic prostatectomy: tech…

2012

What's known on the subject? and What does the study add? Many different approaches have been used to treat bladder neck strictures and urinary incontinence after radical prostatectomy in the past. Most techniques are highly invasive and carry a high risk of complications. The present study describes the use of the Solovov-Badenoch 'pull-through urethroplasty' as well as artificial urinary sphincter implantation.• To report our experience in the management of patients with combined urinary incontinence and stricture after radical prostatectomy with a two-step approach: urethroplasty with a 'pull-through' technique after the Solovov-Badenoch principle; and artificial urinary sphincter (AUS) …

MaleTime FactorsVesico-urethral anastomosiTime FactorUrologyUrinary BladderUrinary incontinenceBladder neck contractureSeverity of Illness IndexFollow-Up StudiePostoperative ComplicationsUrethraRetrospective StudieRecurrenceHumansTreatment FailureAgedRetrospective StudiesProstatectomyAnastomosis SurgicalMiddle AgedRadical prostatectomyUrinary Bladder Neck ObstructionTreatment OutcomeArtificialUrinary sphincterPostoperative ComplicationStrictureHumanFollow-Up Studies
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Bone mineral density of the proximal femur after hip resurfacing arthroplasty: 1-year follow-up study

2011

Abstract Background Hip resurfacing arthroplasty (HRA) is considered a bone-preserving procedure and may eliminate proximal femoral stress shielding and osteolysis. However, in addition to implant-related stress-shielding factors, various patient-related factors may also have an effect on bone mineral density (BMD) of the proximal femur in patients with HRA. Thus, we studied the effects of stem-neck angle, demographic variables, and physical functioning on the BMD of the proximal femur in a one-year follow-up. Methods Thirty three patients (9 females and 24 males) with a mean (SD) age of 55 (9) years were included in the study. BMD was measured two days and 3, 6, and 12 months postoperative…

MaleTime Factorslcsh:Diseases of the musculoskeletal systemBone densityArthroplasty Replacement Hipmedicine.medical_treatmentdual energy X-ray absorptiometry02 engineering and technologySeverity of Illness IndexOsteoarthritis HipAbsorptiometry Photon0302 clinical medicineBone DensityOrthopedics and Sports MedicineFemurProspective StudiesFinlandstress shielding2. Zero hungerBone mineral030222 orthopedicsmedicine.diagnostic_teststem-neck angleMiddle AgedStress shieldingHip resurfacingREPLACEMENTTreatment Outcomemedicine.anatomical_structureFemaleResearch Articlebone remodeling dual energy X-ray absorptiometrymusculoskeletal diseasesmedicine.medical_specialtyeducation0206 medical engineering03 medical and health sciencesFemoral headPOSTERIOR APPROACHRheumatologymedicineHumansFemurPRESERVATIONbone remodelingNECKDual-energy X-ray absorptiometrybusiness.industry3126 Surgery anesthesiology intensive care radiology020601 biomedical engineeringArthroplastySurgeryLogistic Models5-YEARMODESABSORPTIOMETRYFEMORAL-HEADlcsh:RC925-935businessNuclear medicineFollow-Up StudiesBMC Musculoskeletal Disorders
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Finding ways to carry on: stories of vulnerability in chronic illness

2020

Purpose: In this study, we explore the lived experiences of chronic illness in four groups of patients; children with asthma, adolescents with diabetes, young adults with depression, and adult patients with chronic, obstructive pulmonary disease (COPD). Persons living with chronic illness are often designated as vulnerable. This study builds on the assumption that being vulnerable belongs to being human, and that vulnerability also might entail strength and possibilities for growth. Methods: A narrative analysis was undertaken to illuminate how experiences of vulnerability were narrated across the four patient groups, presenting four individual stories, one from each of the patient groups. …

MaleTime Factorslife worldvulnerabilityChronic illnessDevelopmental psychologyPulmonary Disease Chronic Obstructive0302 clinical medicineEmpirical Studies030212 general & internal medicineYoung adultChildlcsh:R5-920Narration030504 nursingDepressionHealth PolicyAge FactorsVDP::Medical disciplines: 700::Health sciences: 800Middle AgedSocial ParticipationPeer reviewVDP::Medisinske Fag: 700::Helsefag: 800phenomenologyFemaleLife worldlcsh:Medicine (General)0305 other medical sciencePsychologychronic illnessResearch ArticleAdultAdolescentPulmonary diseasenarrative analysisNarrative inquiryYoung Adult03 medical and health sciencesDiabetes MellitusHumansAgedAdult patientsLived experiencestoriesAsthmaIssues ethics and legal aspectsChronic DiseaseQuality of LifeFundamentals and skillsGerontology
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