Search results for "indicaxantin"
showing 4 items of 4 documents
Antiproliferative and pro-apoptotic effects of the phytochemical Indicaxanthin on human intestinal (Caco-2) and hepatic (Ha 22T) cancer cell lines
2012
In the present study antiproliferative effects of Indicaxanthin (Ind), a highly bioavailable pigment from the fruits of Opuntia ficus-indica (1), were investigated on a number of human cancer cell lines including hepatocarcinoma cells (HepG2, Ha22T, HUH 7), breast cancer cells (MCF7), cervix epithelial carcinoma (HeLa), and colorectal carcinoma cells (Caco-2). Cytotoxicity of Ind, in a concentration range between 25 to 100 M, was evaluated by Trypan blue exclusion method and MTT assay. Ind caused a clear dose- and time-dependent decrease in the proliferation of Caco-2 and Ha 22T cells with an IC(50) of about 50 M, with minor effect on the other cell lines. Flow cytometric analysis after A…
Composizione comprendente indicaxantina per uso per la prevenzione e il trattamento del diabete mellito di tipo 2, obesità, stress ossidativo e patol…
2021
NUTRIGENOMICS EFFECTS OF PHYTOCHEMICAL INDICAXANTHIN IN in vitro CELL SYSTEMS
2014
Nutrition plays a key role in many aspects of health, indeed epidemiological studies provide evidence that diet can play essential roles in reducing the risk of chronic diseases. Accumulating evidence indicates that dietary compounds (phytochemicals) from fruit and vegetables can modulate multiple cancer-inflammation pathways which are relevant for chemoprevention and are commonly deregulated by epigenetic mechanisms in cancer cells, including drug detoxification, cell cycle regulation, apoptosis induction. Epigenetic refers to heritable alterations in gene expression that do not involve modification of the underlying genetic DNA sequence. Although epigenetic changes are heritable in somati…