Search results for "infarct"

showing 10 items of 1223 documents

Epidural hematoma after cochlear implantation in a 2.5-year-old boy.

2005

OBJECTIVE Report a case of an epidural hematoma after cochlear implantation in a 2.5-year-old boy, the diagnostic and therapeutical emergency management, as well as the postinterventional course and rehabilitation of the child. STUDY DESIGN Retrospective case review. PATIENT Two and a half-year-old boy, suffering from early onset, profound sensorineural hearing loss had been diagnosed at an age of 1.5 years, which had been more severe on the right side initially, but had progressed to bilateral deafness. INTERVENTION AND COMPLICATION: Cochlear implantation on the left side, followed up by an extensive epidural hematoma, causing intracranial compression with a midline shift of 15 mm to the r…

Hematoma Epidural CranialMaleReoperationmedicine.medical_specialtyCritical CareInfarctionBilateral DeafnessAudiologyDeafnessDiagnosis DifferentialInfarction Posterior Cerebral ArteryEpidural hematomaPostoperative ComplicationsMidline shiftmedicine.arteryAnterior cerebral arterymedicineElectrocoagulationHumansDominance CerebralNeurologic Examinationbusiness.industryInfarction Middle Cerebral Arterymedicine.diseaseCochlear ImplantationMagnetic Resonance ImagingMeningeal ArteriesSensory SystemsTentoriumTemporal LobeSurgeryEpistaxisOtorhinolaryngologyIntracranial EmbolismChild PreschoolNeurology (clinical)ImplantOccipital LobeComplicationbusinessTomography X-Ray ComputedFollow-Up StudiesOtologyneurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
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Second trimester uterine arteries pulsatility index is a function of placental pathology and provides insights on stillbirth aetiology: A multicenter…

2022

Introduction: The aim of this study was to investigate the relationships between maternal vascular malperfusions (MVM) and second trimester uterine arteries pulsatility index (UtA-PI) in cases of stillbirth (SB), compared to live-birth (LB) matched controls. Methods: This was a multicentre, observational, matched case-control study performed at five referral maternity centres over a 4-year period including SB and LB control pregnancies at high-risk for preeclampsia (PE) and/or fetal growth restriction (FGR), matched and stratified for UtA-PI MoM quartiles values of the SB cases. Logistic regression was used to assess the rates of each MVM finding, within each increasing MoM quartile subcate…

HematomaPulsatility indexPlacentaObstetrics and GynecologyLogistic regressionMaternal vascular malperfusionStillbirthUltrasonography PrenatalUterine artery Doppler velocimetryUterine ArteryReproductive MedicinePre-EclampsiaInfarctionPregnancyCase-Control StudiesPregnancy Trimester SecondPulsatile FlowHumansFemalePlacental histopathologyLogistic regression; Maternal vascular malperfusion; Placental histopathology; Pulsatility index; Stillbirth; Uterine artery Doppler velocimetryDevelopmental Biology
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Prevalence, risk factor burden, and severity of coronary artery disease in patients with heterozygous familial hypercholesterolemia hospitalized for …

2019

Individuals with heterozygous familial hypercholesterolemia (FH) are at high risk of early myocardial infarction (MI). However, coronary artery disease (CAD) burden of FH remains not well described, especially for French patients.The objective of this study was to assess the prevalence of FH and severity of CAD from a large database of a French regional registry of acute MI.All consecutive patients hospitalized for an acute MI in a multicenter database from 2001 to 2017 were considered. FH was diagnosed using an algorithm adapted from the Dutch Lipid Clinic Network criteria. The prevalence and clinical features of FH and the severity of CAD were assessed.Among the 11,624 patients included i…

Heterozygotemedicine.medical_specialtyEndocrinology Diabetes and Metabolism[SDV]Life Sciences [q-bio]Myocardial InfarctionFamilial hypercholesterolemia030204 cardiovascular system & hematologySeverity of Illness IndexCohort StudiesHyperlipoproteinemia Type IICoronary artery disease03 medical and health sciences0302 clinical medicineRisk FactorsInternal medicinePrevalenceInternal MedicinemedicineHumansIn patientRegistries030212 general & internal medicineMyocardial infarctionRisk factorAcute miLipid clinicAgedAged 80 and overNutrition and Dieteticsbusiness.industryCholesterol LDLMiddle AgedEzetimibemedicine.disease3. Good healthLarge cohortHospitalizationFranceHydroxymethylglutaryl-CoA Reductase InhibitorsCardiology and Cardiovascular Medicinebusiness
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Admission glycemia and in-hospital death following cardiac arrest during myocardial infarction outside hospital

2013

In hospital deathCoronary angiographymedicine.medical_specialtyEjection fractionbusiness.industryHospital mortalitymedicine.diseaseInternal medicineDiabetes mellitusmedicineCardiologyMyocardial infarctionCardiology and Cardiovascular MedicinebusinessEuropean Heart Journal
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In vivo and ex vivo magnetic resonance spectroscopy of the infarct and the subventricular zone in experimental stroke

2015

Ex vivo high-resolution magic-angle spinning (HRMAS) provides metabolic information with higher sensitivity and spectral resolution than in vivo magnetic resonance spectroscopy (MRS). Therefore, we used both techniques to better characterize the metabolic pattern of the infarct and the neural progenitor cells (NPCs) in the ipsilateral subventricular zone (SVZi). Ischemic stroke rats were divided into three groups: G0 (non-stroke controls, n = 6), G1 (day 1 after stroke, n = 6), and G7 (days 6 to 8 after stroke, n =12). All the rats underwent MRS. Three rats per group were analyzed by HRMAS. The remaining rats were used for immunohistochemical studies. In the infarct, both techniques detect…

In vivo magnetic resonance spectroscopyBrain InfarctionMalePathologymedicine.medical_specialtyMRSspectroscopyMagnetic Resonance SpectroscopyTime FactorsHRMASSubventricular zoneRats Sprague-DawleyIn vivoLateral VentriclesmedicineAnimalsStrokebusiness.industryNeurogenesismedicine.diseasestrokeNeural stem cellRatsStrokeneurogenesisDisease Models Animalmedicine.anatomical_structureNeurologyBiomarker (medicine)Original ArticleNeurology (clinical)Cardiology and Cardiovascular MedicinebusinessNeuroscienceEx vivoBiomarkers
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Evaluation of the Haemorheological Determinants in Coronary Heart Disease

1984

Increased blood viscosity has been described in patients with coronary artery disease (1, 2, 3, 4, 5, 6, 7, 8).

Increased blood viscosityCoronary artery diseasemedicine.medical_specialtybusiness.industryInternal medicineBlood viscosityCardiologyMedicineIn patientMyocardial infarctionbusinessmedicine.diseaseCoronary heart disease
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Epidemiological approach of type 2 myocardial infarction : Etiologies, characteristics, treatment and prognosis.

2020

Introduction: Type 2 Myocardial infarction (MI)has been recently defined as an imbalance between oxygen supply and demand, in the absence of atherothromthrombosis. This work aimed to describe the main etiolgies as well as epidemiological, clinical and prognostic characteristics.Method: Data from patients with type 2 MI were collected from the RICO cohort (Observatoire des Infarctus de Cote d'Or). In a complementary work, we analyzed the retrospective data of the emergency department of Dijon University Hospital.Results: Among 4,436 consecutive patients hospitalized for MI in Dijon emergency department over 3 years, 947 (21%) had type 2 MI (median age: 81 years). In the RICO cohort, 4,572 co…

Infactus du myocardeÉpidémiologieMyocardial infarctionEtiologies[SDV.MHEP] Life Sciences [q-bio]/Human health and pathologyÉtiologiesEpidemiologyTyoe 2 myocardial infarctionInfarctus de type 2PronosticPrognosis[SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
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Timing effect of intramyocardial hydrogel injection for positively impacting left ventricular remodeling after myocardial infarction

2015

Intramyocardial injection of various injectable hydrogel materials has shown benefit in positively impacting the course of left ventricular (LV) remodeling after myocardial infarction (MI). However, since LV remodeling is a complex, time dependent process, the most efficacious time of hydrogel injection is not clear. In this study, we injected a relatively stiff, thermoresponsive and bioabsorbable hydrogel in rat hearts at 3 different time points - immediately after MI (IM), 3 d post-MI (3D), and 2 w post-MI (2W), corresponding to the beginnings of the necrotic, fibrotic and chronic remodeling phases. The employed left anterior descending coronary artery ligation model showed expected infar…

InjectionTime FactorsMacrophageMyocardial InfarctionInfarction02 engineering and technology030204 cardiovascular system & hematologyCardiac tissue engineeringAntigens CD31Hydrogel Polyethylene Glycol DimethacrylateHeart Ventricle0302 clinical medicineFibrosisMyocardial infarctionInflammation MediatorVentricular RemodelingIntervention timing021001 nanoscience & nanotechnologyPlatelet Endothelial Cell Adhesion Molecule-1Neutrophil InfiltrationMechanics of MaterialsSelf-healing hydrogelsCardiologyCytokinesFemalemedicine.symptomInflammation Mediators0210 nano-technologymedicine.medical_specialtyMaterials scienceTime FactorHeart VentriclesBiophysicsInflammationBioengineeringCeramics and CompositeAnterior Descending Coronary ArteryArticleInjectionsBiomaterials03 medical and health sciencesInternal medicinemedicineAnimalsMechanics of MaterialVentricular remodelingCytokineActinAnimalMacrophagesMyocardiummedicine.diseaseBiomaterialInjectable materialActinsHydrogelRats Inbred LewCeramics and CompositesLigation
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Biochemical biomarkers alterations in Coronavirus Disease 2019 (COVID-19)

2020

Abstract Coronavirus Disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a respiratory disease, which can evolve into multi-organ failure (MOF), leading to death. Several biochemical alterations have been described in COVID-19 patients. To date, many biomarkers reflecting the main pathophysiological characteristics of the disease have been identified and associated with the risk of developing severe disease. Lymphopenia represents the hallmark of the disease, and it can be detected since the early stage of infection. Increased levels of several inflammatory biomarkers, including c-reactive protein, have been found in COVID-19 patients and associ…

Kidney DiseaseClinical BiochemistryMyocardial InfarctionMedicine (miscellaneous)Disease030204 cardiovascular system & hematologySeverity of Illness Index0302 clinical medicineBiomarkers Coronavirus Infection030212 general & internal medicinebiochemical alterationAged 80 and overHealth PolicyLiver DiseasesMusclesLiver DiseaseRespiratory diseaseBlood Coagulation DisordersWater-Electrolyte BalancePathophysiologyC-Reactive ProteinDisease ProgressionCytokinesbiomarkerMuscleKidney DiseasesLiver dysfunctionCoronavirus InfectionsHumanCoronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Pneumonia Viralmacromolecular substances03 medical and health sciencesBetacoronavirusLymphopeniamedicineHumansCytokinePandemicsAgedInflammationBlood Coagulation DisorderBetacoronavirubusiness.industrySARS-CoV-2Biochemistry (medical)Public Health Environmental and Occupational HealthCOVID-19Biochemical biomarkersmedicine.diseaseImmunologyCytokine stormbusinesslaboratoryBiomarkers
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Early and midterm outcomes of bioresorbable vascular scaffolds for ostial coronary lesions: insights from the GHOST-EU registry.

2016

Aims: We aimed to investigate the outcomes of bioresorbable vascular scaffolds (BVS) in coronary ostial lesions. Ostial lesions represent a challenging angiographic subset, with higher event rates compared with non-ostial lesions. BVS might be associated with advantages over the long term, but their safety in this setting remains to be explored. Methods and results: Procedural and 12-month follow-up data from consecutive patients treated with BVS for lesions located at the ostium of the right (RCA), left anterior (LAD) or circumflex (LCX) coronary in 11 European centres were collected. The primary device-oriented endpoint was defined as a combination of cardiovascular death, target vessel m…

LCX (29Target lesionMale52%). Patients presenting with ostial lesions did not differ from the remaining cohort except for a higher incidence of prior revascularisation. Predilation was performed in 97% of the lesions (vs. 96% in non-ostialp= 0.035)medicine.medical_treatmentMyocardial Infarction304 patients with a mean age of 62 +/- 11years. There were 90 ostial lesions (5.8%) in 84 patients (6.4%) located at the ostial RCA (14Coronary Artery Disease030204 cardiovascular system & hematologyCoronary artery diseasebut their safety in this setting remains to be explored. Methods and results: Procedural and 12-month follow-up data from consecutive patients treated with BVS for lesions located at the ostium of the right (RCA)0302 clinical medicineAbsorbable Implants030212 general & internal medicineMyocardial infarctionCircumflexRegistriesTissue Scaffolds32%)Drug-Eluting StentsMiddle AgedThrombosisCoronary VesselsAims: We aimed to investigate the outcomes of bioresorbable vascular scaffolds (BVS) in coronary ostial lesions. Ostial lesions represent a challenging angiographic subset with higher event rates compared with non-ostial lesions. BVS might be associated with advantages over the long term but their safety in this setting remains to be explored. Methods and results: Procedural and 12-month follow-up data from consecutive patients treated with BVS for lesions located at the ostium of the right (RCA) left anterior (LAD) or circumflex (LCX) coronary in 11 European centres were collected. The primary device-oriented endpoint was defined as a combination of cardiovascular death target vessel myocardial infarction or target lesion revascularisation. The database included a total of 1549 lesions in 1304 patients with a mean age of 62 +/- 11years. There were 90 ostial lesions (5.8%) in 84 patients (6.4%) located at the ostial RCA (14; 16%) LCX (29; 32%) or LAD (47; 52%). Patients presenting with ostial lesions did not differ from the remaining cohort except for a higher incidence of prior revascularisation. Predilation was performed in 97% of the lesions (vs. 96% in non-ostial p= 0.618) post-dilation in 43% (versus 58% in the non-ostial group p= 0.008). At quantitative coronary angiography treatment of ostial lesions was associated with higher residual stenosis (30% [23-41] vs. 26% [20-37] p= 0.035) but no difference in minimum lumen diameter existed (p= 0.447). Follow-up data were available at 385 [362-465] days. The 12-month Kaplan-Meier estimated rates of scaffold thrombosis were 4.9% and 2.0% (ostial and non-ostial lesion groups respectively log-rank p= 0.005). The device-oriented composite endpoint occurred respectively in 12.6% and 4.6% at 12 months (log-rank p= 0.001). Treatment of ostial lesions was an independent predictor of this endpoint (p= 0.0025 HR 2.65 [1.41-4.97]).OstiumAims: We aimed to investigate the outcomes of bioresorbable vascular scaffolds (BVS) in coronary ostial lesions. Ostial lesions represent a challenging angiographic subsetTreatment Outcomein 12.6% and 4.6% at 12 months (log-rank p= 0.001). Treatment of ostial lesions was an independent predictor of this endpoint (p= 0.0025CardiologyFemale549 lesions in 1medicine.symptomCardiology and Cardiovascular MedicineAdultpost-dilation in 43% (versus 58% in the non-ostial groupmedicine.medical_specialtyor LAD (47HR 2.65 [1.41-4.97])but no difference in minimum lumen diameter existed (p= 0.447). Follow-up data were available at 385 [362-465] days. The 12-month Kaplan-Meier estimated rates of scaffold thrombosis were 4.9% and 2.0% (ostial and non-ostial lesion groupsrespectivelyLesion03 medical and health sciencesPercutaneous Coronary Interventionwith higher event rates compared with non-ostial lesions. BVS might be associated with advantages over the long termleft anterior (LAD) or circumflex (LCX) coronary in 11 European centres were collected. The primary device-oriented endpoint was defined as a combination of cardiovascular deathInternal medicinemedicineHumanstarget vessel myocardial infarction or target lesion revascularisation. The database included a total of 1Agedp= 0.008). At quantitative coronary angiographybusiness.industryPercutaneous coronary interventionp= 0.618)treatment of ostial lesions was associated with higher residual stenosis (30% [23-41] vs. 26% [20-37]log-rank p= 0.005). The device-oriented composite endpoint occurredmedicine.diseaseSurgery16%)businessEuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology
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