Search results for "infection"

showing 10 items of 3717 documents

All that glitters is not gold: A spinal epidural empyema following epidural steroid injection

2020

Background: Therapeutic epidural spinal injections (ESIs) of steroids are one of the most common nonsurgical management modalities employed for alleviating pain due to chronic persistent lumbar spinal disease. However, it is well documented that they have significant risks and complications without any long-term efficacy. ESI may result in epidural empyema which may be difficult to diagnose with delays resulting in significant permanent neurological sequelae. Case Description: A 45-year-old female presented with a lumbar spinal epidural empyema after receiving ESI for low back and right leg pain due to a lumbar disc herniation. Laboratory studies showed elevations of multiple inflammatory …

musculoskeletal diseasesmedicine.medical_specialtymedicine.medical_treatmentSpinal epidural abscessCauda equina syndromeCase ReportSpinal disease03 medical and health sciences0302 clinical medicineLumbarmedicine030212 general & internal medicineSpinal procedureSettore MED/27 - Neurochirurgiabusiness.industryEpidural steroid injectionLumbar degenerative disease Spinal procedure Pain management Spinal epidural abscess Spinal infectionSpinal infectionLaminectomymedicine.diseaseEmpyemaPain managementSurgeryLumbar degenerative diseaseSurgeryNeurology (clinical)Thecal sacbusinessComplication030217 neurology & neurosurgerySurgical Neurology International
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Treatment with a CO-releasing molecule (CORM-3) reduces joint inflammation and erosion in murine collagen-induced arthritis.

2008

Contains fulltext : 70589.pdf (Publisher’s version ) (Closed access) OBJECTIVE: CO-releasing molecules (CO-RMs) are a novel class of anti-inflammatory agents. We have examined the possible therapeutic effects of CORM-3 in collagen-induced arthritis (CIA). METHODS: Arthritis was induced in DBA-1/J mice by type II collagen. Animals were treated with CORM-3 (5 and 10 mg/kg/day, intraperitoneally) or the inactive compound iCORM-3 (10 mg/kg/day, intraperitoneally) unable to release CO, from days 22 to 31. Production of anti-type II collagen antibodies, cytokines and cartilage olimeric matrix protein (COMP) was evaluated by enzyme-linked immunosorbent assay, and prostaglandin E(2) (PGE(2)) by rad…

musculoskeletal diseasesmedicine.medical_treatmentImmunologyAnti-Inflammatory AgentsDrug Evaluation PreclinicalType II collagenArthritisInflammationPharmacologyAuto-immunity transplantation and immunotherapy [N4i 4]DinoprostoneGeneral Biochemistry Genetics and Molecular BiologyMiceRheumatologyOrganometallic CompoundsPerception and Action [DCN 1]medicineAnimalsImmunology and AllergyChronic inflammation and autoimmunity [UMCN 4.2]Dose-Response Relationship Drugbiologybusiness.industryRANK LigandInterleukinIntercellular Adhesion Molecule-1medicine.diseaseArthritis ExperimentalPathogenesis and modulation of inflammation [N4i 1]Cellular infiltrationCyclooxygenase 2Mice Inbred DBARANKLImmunologybiology.proteinCytokinesTumor necrosis factor alphaMicrobial pathogenesis and host defense [UMCN 4.1]Inflammation Mediatorsmedicine.symptombusinessInfection and autoimmunity [NCMLS 1]Heme Oxygenase-1Immunity infection and tissue repair [NCMLS 1]Prostaglandin E
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Case report: necrotizing fascitis of odontogenenic origin in a subject affected by uncompensated type 2 diabetes mellitus

2008

necrotizing fascitis infections complications
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Etiological factors of chronic hepatitis in Italy: a 2014 national survey.

2017

Background The last Italian prevalence survey on chronic hepatitis (CH) conducted in 2001 showed that the hepatitis C virus (HCV) was the main agent associated with CH. Aim The aim of this study was to evaluate epidemiological changes in CH occurring after 13 years. Patients and methods Enrollment of 1392 CH consecutive patients referred to 16 Italian liver units in 2014 scattered all over the country (four in the North, four in the Center, four in the South, and four in the Islands) was performed. Results The mean age of the patients was 58.3 years, with a sex ratio (male/female) of 1.5. HCV infection (also with other etiologies) continues to be the most prevalent etiology (58.1%). However…

nonalcoholic fatty liver diseaseAdultMalemedicine.medical_specialtyPediatricsTime FactorsTime FactorAdolescentHepatitis C virusmedicine.disease_causemetabolic syndrome03 medical and health sciencesYoung Adult0302 clinical medicinechronic hepatitiRisk FactorsEpidemiologyNonalcoholic fatty liver diseasemedicinePrevalenceHumansAgedHepatitis ChronicHepatitisAged 80 and overHepatologybusiness.industryRisk FactorGastroenterologyEntecavirHepatitis CHealth SurveyHepatitis BHepatitis C ChronicMiddle Agedmedicine.diseaseHealth SurveysItaly030220 oncology & carcinogenesisEtiology030211 gastroenterology & hepatologyFemalehepatitis C virus infectionbusinessHumanmedicine.drugEuropean journal of gastroenterologyhepatology
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Single-Center-Single-Blinded Clinical Trial to Evaluate the Efficacy of a Nutraceutical Containing Boswellia Serrata, Bromelain, Zinc, Magnesium, Hon…

2022

Some nutraceuticals have been studied as supportive treatment for fighting upper respiratory tract infection and middle ear disease. Our study aims at evaluating the effect of a specific oral supplementation in the treatment of pediatric otits media. The subjects were randomly assigned by the physician (single-blinded study) to one of three groups: Control Group (CG), Treatment Group 1 (TG1), or Treatment Group 2 (TG2). Both TG were treated with Flogostop Duo (for 20 days—TG1 or 30 days—TG2) in combination with the standard treatment, while CG underwent standard treatment only. The standard treatment was nasal aerosol with Fluticasone and Mucolytic, and nasal washing with hypertonic solutio…

nutraceuticalsLeadership and ManagementHealth Policyauditory testbromelainclinical trialHealth Informaticsnasal spraynutraceuticals; clinical trial; Boswellia; bromelain; upper respiratory infection; Otitis Media; auditory test; nasal spray; quality of lifeOtitis Mediaquality of lifeHealth Information ManagementBoswelliaupper respiratory infectionHealthcare
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Mucocutaneous diseases with manifestations in the head and neck region: 24 years of experience in a Dermatology service

2023

This study aimed to evaluate the clinicopathological features of mucocutaneous diseases with manifestation in the head and neck region. A retrospective analysis of a dermatology reference center database was carried out. Over 24 years. Clinicopathological data were collected from medical records and the data was analyzed by descriptive statistics. A total of 11.538 medical records were analyzed, being 152 cases of mucocutaneous diseases with manifestations in the head and neck region. Cutaneous lupus erythematosus was the most prevalent diagnosis (66.4%). Face (44.1%), females (79.6%), and patients with 45 years mean age were the most common features. In the oral cavity, the most affected r…

oral mucosaparacoccidioidomycosisOtorhinolaryngologyfungal infectionneglected diseasesoral medicineSurgerymycosesGeneral Dentistryoral manifestationsUNESCO:CIENCIAS MÉDICASsouth american blastomycosisMedicina Oral Patología Oral y Cirugia Bucal
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Integrative Clinical Research

2022

This book embraces a comprehensive range of research across several disciplines, providing insights and fresh perspectives on clinical topics, emphasizing the integrative medical approach. The book also addresses an increasing role of artificial intelligence in the development of clinical methodologies, research, and patient-oriented care. The authors share expertise and experience in rehabilitation medicine whose healing-effects particularly depend on the interaction between the therapist and patient. Chapters present novel approaches in manual rehabilitative therapy of common painful and disabling neuromuscular ailments, exemplified but not limited to low back pain and migraine. The myofa…

pain medicinefrailityArtificial intelligencerespiratory infectionsdiabetesprecision medicinesleep-disordersmigrainepregnangy
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CLINICAL IMPLICATIONS OF COVID-19 AND MEASURES IMPLEMENTED BY DENTAL PRACTITIONERS IN CAMBODIA

2022

Objective: The objective of this study was to evaluate the changes in the attitude of dentists in Cambodia towards the pandemic and understand the newer measures implemented to restrict the spread of the SARS-CoV-2 infection. Methods: A structured self-administered questionnaire was developed at the University of Puthisastra, Phnom Penh and provided to the participants for data collection. The questionnaire was developed using Google survey to collect demographic data followed by information regarding the working conditions, newly implemented measures during the pandemic and the attitude of Cambodian dentists towards the threat of infections. Results: Out of a total of 130 dentists that wer…

pandemicconsultationsCOVID-19dentistsinfection
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Evolutionary Dynamics of Pathoadaptation Revealed by Three Independent Acquisitions of the VirB/D4 Type IV Secretion System in Bartonella

2017

The α-proteobacterial genus Bartonella comprises a group of ubiquitous mammalian pathogens that are studied as a model for the evolution of bacterial pathogenesis. Vast abundance of two particular phylogenetic lineages of Bartonella had been linked to enhanced host adaptability enabled by lineage-specific acquisition of a VirB/D4 type IV secretion system (T4SS) and parallel evolution of complex effector repertoires. However, the limited availability of genome sequences from one of those lineages as well as other, remote branches of Bartonella has so far hampered comprehensive understanding of how the VirB/D4 T4SS and its effectors called Beps have shaped Bartonella evolution. Here, we repor…

parallel evolution0301 basic medicineBartonellaAMPylation; bacterial effector; filamentation induced by cAMP; parallel evolutionVirulence FactorsIn silico030106 microbiologyBiologyfilamentation induced by cAMPGenomeEvolution MolecularType IV Secretion Systems03 medical and health sciencesBacterial ProteinsBartonella InfectionsGeneticsAMPylationHumansEvolutionary dynamicsBacterial Secretion SystemsPhylogenyEcology Evolution Behavior and SystematicsPhylogenetic treeEffectorbiology.organism_classificationbacterial effectorVirology030104 developmental biologyEvolutionary biologyFilamentation induced by cAMP; AMPylation; Parallel evolution; Bacterial effectorHost-Pathogen InteractionsParallel evolutionAdaptationBartonellaResearch Article
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cayol_texte_tables_figures_ESM from Borrelia afzelii alters reproductive success in a rodent host

2018

Supplementary material from "Borrelia afzelii alters reproductive success in a rodent host". Detailed material and methods, supplementary tables, figures and results.

parasitic diseasesbacterial infections and mycoses
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