Search results for "infiltration"

showing 10 items of 291 documents

P729PD-1/PD-L1 axis contributes to infarct size in ST elevation myocardial infarction

2014

Programmed death-1 (PD-1) and Programmed death-1 ligand (PD-L1) regulate immune response. Previous studies associate an immune deregulation in ST-elevation myocardial infarction STEMI. We recruited 100 patients with a first STEMI treated with reperfusion. In all patients PD-1 and PD-L1 expression was studied 24 h post-reperfusion in peripheral blood mononuclear cells (PBMCs), by means of flow cytometry and molecular biology. PD-1 and PD-L1 expression was serially analyzed in the first 20 patients before reperfusion and 24h, 96h and 30 days afterwards. Results were compared with 30 age- and sex-matched controls. Cardiac Magnetic Resonance was used to quantify infarct size 1-week after infarc…

medicine.medical_specialtymedicine.diagnostic_testbiologyPhysiologybusiness.industryInfarctionmedicine.diseasePeripheral blood mononuclear cellFold changeFlow cytometryReperfusion therapyPhysiology (medical)Internal medicinePD-L1Cardiologybiology.proteinMedicinecardiovascular diseasesMyocardial infarctionCardiology and Cardiovascular MedicinebusinessInfiltration (medical)Cardiovascular Research
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Microwave response of bulk MgB2 samples of different granularity

2006

The microwave response of three high-density bulk MgB2 samples has been investigated in the linear and nonlinear regimes. The three samples, characterized by different mean size of grains, have been obtained by reactive infiltration of liquid Mg in powdered B preforms. The linear response has been studied by measuring the microwave surface impedance; the nonlinear response by detecting the power radiated by the sample at the second-harmonic frequency of the driving field. Our results suggest that bulk MgB2 prepared by the liquid Mg infiltration technique is particularly promising for manufacturing resonant cavities operating at microwave frequencies.

microwave responseSuperconductivityHistoryMaterials scienceField (physics)Condensed matter physicsCondensed Matter - SuperconductivitySettore FIS/01 - Fisica SperimentaleMicrowave responseFOS: Physical sciencesInfiltration (HVAC)Computer Science ApplicationsEducationSuperconductivity (cond-mat.supr-con)Nonlinear systemmagnesium diborideCondensed Matter::SuperconductivitySurface impedanceGranularityComposite materialnonlinear effectsMicrowave
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The soluble terminal complement complex (SC5b-9) up-regulates osteoprotegerin expression and release by endothelial cells: Implications in rheumatoid…

2009

Objective. Complement activation products contribute to a large number of inflammatory diseases, including RA. We have investigated whether osteoprotegerin (OPG) may concur with the soluble terminal complement complex (SC5b-9) to the inflammatory cascade characterizing RA. Methods. Levels of SC5b-9 and OPG in the plasma and SF of patients with active RA were determined by ELISA. The presence of SC5b-9 and OPG in RA synovial lesions was analysed by immunohistochemistry. Cultured endothelial cells were used for in vitro leucocyte/endothelial cell adhesion assays. In addition, endothelial cells were exposed to SC5b-9 in order to evaluate the effects on the production of OPG protein, as well as…

musculoskeletal diseasesAdultMalemedicine.medical_specialtyComplement systemEndotheliumNeutrophilsArthritisInflammationComplement Membrane Attack ComplexArthritis RheumatoidEndothelium; Osteoprotegerin; Inflammation; Complement systemRheumatologyOsteoprotegerinInternal medicineCell AdhesionMedicineHumansPharmacology (medical)EndotheliumCells CulturedAgedInflammationEndothelial CellDose-Response Relationship Drugbusiness.industryNeutrophilSynovial MembraneOsteoprotegerinEndothelial CellsMiddle Agedmedicine.diseaseIn vitroComplement systemUp-RegulationEndothelial stem cellEndocrinologymedicine.anatomical_structureNeutrophil InfiltrationFemaleComplement system; Endothelium; Inflammation; Osteoprotegerin; Adult; Aged; Arthritis Rheumatoid; Cell Adhesion; Cells Cultured; Complement Membrane Attack Complex; Dose-Response Relationship Drug; Endothelial Cells; Endothelium Vascular; Female; Humans; Male; Middle Aged; Neutrophil Infiltration; Neutrophils; Osteoprotegerin; Synovial Membrane; Up-Regulation; Rheumatology; Pharmacology (medical)Endothelium Vascularmedicine.symptombusinessComplement membrane attack complexHuman
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Leukodiapedesis and leukocyte migration in the leptomeninges and in the subarachnoid space.

1981

Pleocytosis in cerebrospinal fluid and infiltration of the leptomeningeal tissue have been studied after injection of ferritin into the subarachnoid space (SAS) of cats. The most important source of granulocytes in the leptomeninges are the relatively large veins of the pia mater, which have very thin walls. Passing between the lining cells of the pia mater the granulocytes leave the connective tissue space of the pia mater and reach the SAS. Leukodiapedesis has also been observed in veins crossing the SAS. During this process, gaps between the lining cells of the perivascular leptomeningeal sheath may develop. There are two possible ways for the granulocytes to pass from the vascular pia m…

musculoskeletal diseasesLeukocyte migrationDura materSubarachnoid SpaceVeinsCerebrospinal fluidCell MovementmedicineLeukocytesAnimalsintegumentary systemPia materChemistryLeptomeningesMeningesAnatomymusculoskeletal systemmedicine.diseasemedicine.anatomical_structurenervous systemNeurologyCatsPia MaterNeurology (clinical)Dura MaterSubarachnoid spaceArachnoidInfiltration (medical)Journal of neurology
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Die Sonographie der Lendenwirbelsäule und des lumbosakralen Überganges - Sonoanatomie und Möglichkeiten der sonographisch gesteuerten Facettengelenks…

2008

QUESTION Is sonography helpful in facet joint infiltration of the lumbar spine? METHOD The sonoanatomy of the lumbar spine and the of lumbosacral junction was examined and described in a skeleton and in 10 volunteers. One representative cross section and 3 longitudinal sections were defined. According to these results (no neurological symptoms) the possibilities of ultrasound guided infiltration of the facet joints was examined in 78 patients (36 female, 42 male, average age 55 y., 38-78 y.) with chronic low back pain and increase of pain by hyperextension. 5 ml Carbostesin partially in combination with steroids were applied to each joint. In all cases the tip of the syringe could be placed…

musculoskeletal diseasesbusiness.industrymedicine.diseaseUltrasound guidedFacet jointChronic low back painmedicine.anatomical_structuremedicineOrthopedics and Sports MedicineSurgerySpinal canalLumbar spineNuclear medicinebusinessInfiltration (medical)Lumbosacral jointCarbostesinZeitschrift für Orthopädie und ihre Grenzgebiete
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Treatment with a CO-releasing molecule (CORM-3) reduces joint inflammation and erosion in murine collagen-induced arthritis.

2008

Contains fulltext : 70589.pdf (Publisher’s version ) (Closed access) OBJECTIVE: CO-releasing molecules (CO-RMs) are a novel class of anti-inflammatory agents. We have examined the possible therapeutic effects of CORM-3 in collagen-induced arthritis (CIA). METHODS: Arthritis was induced in DBA-1/J mice by type II collagen. Animals were treated with CORM-3 (5 and 10 mg/kg/day, intraperitoneally) or the inactive compound iCORM-3 (10 mg/kg/day, intraperitoneally) unable to release CO, from days 22 to 31. Production of anti-type II collagen antibodies, cytokines and cartilage olimeric matrix protein (COMP) was evaluated by enzyme-linked immunosorbent assay, and prostaglandin E(2) (PGE(2)) by rad…

musculoskeletal diseasesmedicine.medical_treatmentImmunologyAnti-Inflammatory AgentsDrug Evaluation PreclinicalType II collagenArthritisInflammationPharmacologyAuto-immunity transplantation and immunotherapy [N4i 4]DinoprostoneGeneral Biochemistry Genetics and Molecular BiologyMiceRheumatologyOrganometallic CompoundsPerception and Action [DCN 1]medicineAnimalsImmunology and AllergyChronic inflammation and autoimmunity [UMCN 4.2]Dose-Response Relationship Drugbiologybusiness.industryRANK LigandInterleukinIntercellular Adhesion Molecule-1medicine.diseaseArthritis ExperimentalPathogenesis and modulation of inflammation [N4i 1]Cellular infiltrationCyclooxygenase 2Mice Inbred DBARANKLImmunologybiology.proteinCytokinesTumor necrosis factor alphaMicrobial pathogenesis and host defense [UMCN 4.1]Inflammation Mediatorsmedicine.symptombusinessInfection and autoimmunity [NCMLS 1]Heme Oxygenase-1Immunity infection and tissue repair [NCMLS 1]Prostaglandin E
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The Mechanical Impact of Water Affected the Soil Physical Quality of a Loam Soil under Minimum Tillage and No-Tillage: An Assessment Using Beerkan Mu…

2021

The multi-height (low, L = 3 cm

soil physical quality010504 meteorology & atmospheric sciencesSoil scienceinfiltration01 natural scienceslcsh:AgricultureField capacitySoil managementMinimum tillagesoil sealingsoil water retentionSoil retrogression and degradation0105 earth and related environmental sciencesNature and Landscape ConservationBEST-steadyGlobal and Planetary ChangeEcologySoil physicslcsh:S04 agricultural and veterinary sciencesInfiltration (hydrology)LoamSoil water040103 agronomy & agriculture0401 agriculture forestry and fisheriesEnvironmental scienceLand
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A simple field method to measure the hydrodynamic properties of soil surface crust

2013

The hydraulic resistance of the surface crust was determined by a combination of two infiltrometric techniques: first, a surface measurement of steady-state infiltration rate is conducted by a mini-disk tension infiltrometer (MDI); then, the surface crust is removed, its thickness is measured, and a ponded infiltration test is performed at the same site. The Beerkan Estimation of Soil Transfer parameters (BEST) method is applied to estimate the hydraulic properties of the underlying soil provided the particlesize distribution and the bulk density are known. Under the assumption of a unit gradient of hydraulic head below the soil crust, the pressure head at the interface crust-soil is derive…

soil surface crust mini disk tension infiltrometer BEST procedureBEST procedure; Mini disk tension infiltrometer; Soil surface crust; Industrial and Manufacturing Engineering; Mechanical Engineering; BioengineeringWater flowMechanical Engineeringlcsh:SBioengineeringCrustInfiltration (HVAC)lcsh:S1-972Industrial and Manufacturing Engineeringlcsh:AgricultureHydraulic headSoil surface crustHydraulic conductivityMini disk tension infiltrometerSoil crustLoamSoil surface crust mini disk tension infiltrometer BEST procedure.InfiltrometerGeotechnical engineeringBEST procedurelcsh:Agriculture (General)MathematicsJournal of Agricultural Engineering
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Modelling urban stormwater impact mitigation by using bmps and storage tanks

2005

The continuous growth of urban areas and the increasing public awareness about environmental impact of stormwater raised high interest on quality impact on the receiving water bodies. Indeed, in the last decades, large efforts have been provided for improving urban drainage systems in order to mitigate environmental impacts. In the present paper, a simplified modelling approach has been developed in order to evaluate the mitigation efficiency of different BMP schemes including infiltration and storage facilities and both considering possible distributed controls and centralised structures. The main goals of the research are the simulation of BMP efficiency in different operational condition…

stormwater infiltrationBest Management Practicesurban water qualitysimulationreceiving water impact
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Hydro-mechanical modelling of MX-80 bentonite: one dimensional study

2016

As a first step towards modelling the coupled Thermo-Hydro-Mechanical-Chemical (THMC) behaviour of bentonite, the Barcelona Basic Model (BBM) has been implemented into Numerrin finite element code. This model has been fully coupled with the single phase flow equation for unsaturated soils which models liquid water transport. Suction obtained from solving the flow equation is used as an input for the BBM model and the volumetric deformations from the mechanical analysis are used to update the pore water pressure field. As an alternative, BBM is used alongside the Kröhn’s model which assumes that bentonite re-saturation is mainly driven by water vapour diffusion. The paper simulates one dimen…

ta212lcsh:GE1-350Water transportMaterials scienceLiquid water0211 other engineering and technologies02 engineering and technology010501 environmental sciences01 natural sciencesInfiltration (hydrology)Pore water pressurePhysical phenomenaSoil waterBentoniteGeotechnical engineering021108 energyWater vaporlcsh:Environmental sciences0105 earth and related environmental sciences
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