Search results for "informatics"

showing 10 items of 2542 documents

The effect of ezetimibe on NAFLD

2015

NAFLD has become the most common liver disorder in countries, where obesity, type 2 diabetes mellitus, dyslipidemia, and metabolic syndrome are common. The strong association between these conditions and the risk of cardiovascular disease make treatment crucial. Possible interventions for NAFLD target excess body weight, insulin resistance, inflammation, oxidative stress or intestinal lipid absorption. Administration of combination therapy with a statin plus ezetimibe, associated with lifestyle changes, may represent an effective strategy because of the strong reduction in low-density lipoprotein cholesterol levels. Combination therapy is often more effective, especially when complementary …

medicine.medical_specialtyStatinSettore MED/09 - Medicina InternaCombination therapymedicine.drug_classBioinformaticsLiver disorderInsulin resistanceEzetimibeInternal medicineInternal MedicineAnimalsHumansMedicinebusiness.industryAnticholesteremic AgentsIntestinal lipid absorptionnutritional and metabolic diseasesGeneral MedicineLipid Metabolismmedicine.diseaseEzetimibeTreatment OutcomeEndocrinologyCholesterolLiverAzetidinesDrug Therapy CombinationMetabolic syndromebusinessCardiology and Cardiovascular MedicineNon-alcoholic steatohepatitiDyslipidemiamedicine.drugNon-alcoholic fatty liver disease
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High-Sensitivity C-Reactive Protein and Statin Initiation

2014

The assessment of cardiovascular risk and treatment of cardiovascular diseases are major public health issues worldwide. Inflammation is now recognized as a key regulatory process that links multiple risk factors for atherosclerosis. The substantial number of patients having cardiovascular events lack commonly established risk factors. The utility of high-sensitivity C-reactive protein (hsCRP), a circulating biomarker related to inflammation, may provide additional information in risk prediction. This review will consider the impact of hsCRP level on initiation of statin therapy.

medicine.medical_specialtyStatinmedicine.drug_classInflammationBioinformaticsMultiple risk factorsRisk AssessmentPredictive Value of TestsRisk FactorsmedicineHumanscardiovascular diseasesDyslipidemiasInflammationbiologybusiness.industryPublic healthC-reactive protein3. Good healthCirculating biomarkersC-Reactive ProteinTreatment OutcomeCardiovascular DiseasesPractice Guidelines as TopicPhysical therapybiology.proteinBiomarker (medicine)Statin therapyHydroxymethylglutaryl-CoA Reductase InhibitorsInflammation Mediatorsmedicine.symptomCardiology and Cardiovascular MedicinebusinessBiomarkersAngiology
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Experiences from cross-cultural collaboration in health campaigns in Tanzania: a qualitative study

2021

Abstract Background Health campaigns are an important aspect of preventive health work. They can aim to improve health literacy in rural areas where residents lack access to health information and knowledge, and to improve both local and global health through cross-cultural collaboration. In Tanga District, Tanzania, exchange students and local youths participate together with Tanga International Competence Centre (TICC) to plan and accomplish health campaigns in local communities. The aim of this study was to explore the participants’ experiences with the cross-cultural collaboration in the planning and delivery of TICC’s health campaigns. Methods This study used a focused ethnographic app…

medicine.medical_specialtyTanga international competence Centre (TICC)Health campaignsHealth literacyHealth informaticsGlobal healthmedicineHealth policyMedical educationPublic healthVDP::Medisinske Fag: 700::Helsefag: 800::Samfunnsmedisin sosialmedisin: 801business.industryResearchPublic healthPublic Health Environmental and Occupational HealthHealth services researchHealth literacyHealth promotionHealth informationHealth promotionCross-cultural collaborationQualitative studyPublic aspects of medicineRA1-1270PsychologybusinessQualitative researchArchives of Public Health
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Functional roles of the sweet taste receptor in oral and extraoral tissues

2014

International audience; Purpose of review: This review summarizes and discusses the current knowledge about the physiological roles of the sweet taste receptor in oral and extraoral tissues. Recent findings: The expression of a functional sweet taste receptor has been reported in numerous extragustatory tissues, including the gut, pancreas, bladder, brain and, more recently, bone and adipose tissues. In the gut, this receptor has been suggested to be involved in luminal glucose sensing, the release of some satiety hormones, the expression of glucose transporters, and the maintenance of glucose homeostasis. More recently, the sweet taste receptor was proposed to regulate adipogenesis and bon…

medicine.medical_specialtyTasteinsulinobesitysweetenerProtein ConformationUrinary BladderMedicine (miscellaneous)BiologyBioinformaticsReceptors G-Protein-Coupled03 medical and health sciences0302 clinical medicinestomatognathic systemInternal medicineInsulin Secretion[SDV.IDA]Life Sciences [q-bio]/Food engineeringmedicineAnimalsHumans[SPI.GPROC]Engineering Sciences [physics]/Chemical and Process EngineeringLymphocytesInsulin secretionReceptor030304 developmental biologyCARBOHYDRATES: Edited by Luc Tappy and Bettina Mittendorfer0303 health sciencesPolymorphism GeneticNutrition and Dieteticsdiabetesdigestive oral and skin physiologyfood and beveragesHeartSweetening agentsSweet tastetaste receptor functionTaste BudsGastrointestinal TractEndocrinologyAdipose TissuecarbohydrateSweetening AgentsTasteModels Animal030217 neurology & neurosurgeryInsulin metabolism
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A Web-Based Telemanagement System for Patients With Complex Inflammatory Bowel Disease: Protocol for a Randomized Controlled Clinical Trial

2018

Background: Telemedicine has been successfully used to provide inflammatory bowel disease (IBD) patients with health care services remotely via the implementation of information and communications technology, which uses safe and feasible apps that have been well accepted by patients in remission. However, the design of telemedicine apps in this setting involves difficulties that hinder the adherence of patients to the follow-up plans and the efficacy of these systems to improve disease activity and quality of life. Objective: This study aimed to evaluate the development of a Web platform, Telemonitoring of Crohn Disease and Ulcerative Colitis (TECCU), for remote monitoring of patients with …

medicine.medical_specialtyTelemedicine020205 medical informatics02 engineering and technologyInflammatory bowel diseaselaw.invention03 medical and health sciences0302 clinical medicineQuality of life (healthcare)information technologyRandomized controlled trialinflammatory bowel diseaselawHealth careProtocol0202 electrical engineering electronic engineering information engineeringmedicineeHealthDisease management (health)Intensive care medicineulcerative colitisbusiness.industryCrohn diseaseGeneral Medicinemedicine.diseaseClinical trialeHealth030211 gastroenterology & hepatologytelemedicinebusinessJMIR Research Protocols
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Telemedicine in the treatment of patients with inflammatory bowel disease.

2017

Inflammatory bowel disease (IBD) is a chronic and relapsing disorder with significant medical, social and financial impacts. IBD patients require continuous follow-up, and healthcare resource use in this context increases over time. In the last decade, telemedicine has influenced the treatment of chronic diseases like IBD via the application of information and communication technologies to provide healthcare services remotely. Telemedicine and its various applications (telemanagement, teleconsulting and tele-education) enable closer follow-up and provide education resources that promote patient empowerment, encouraging treatment optimisation over the entire course of the disease. We describ…

medicine.medical_specialtyTelemedicine020205 medical informaticsPatient EmpowermentContext (language use)02 engineering and technologyDiseaseHealth outcomesInflammatory bowel disease03 medical and health sciences0302 clinical medicineHealth care0202 electrical engineering electronic engineering information engineeringmedicineHumansIntensive care medicineInternetbusiness.industrymedicine.diseaseInflammatory Bowel Diseasesdigestive system diseasesTelemedicineSurgeryResource use030211 gastroenterology & hepatologybusinessGastroenterologia y hepatologia
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The Metabolic Syndrome as a Prohypertensive State

2008

describe the ability of MetS to pre-dict the development of hypertension. The conclusions of this interesting study (CRISPS2) support the concept that the MetS, regardless of the criteria used to define it (NCEP-ATPIII or IDF), may be considered, at least in part, as a potentially reversible prohypertensive state.

medicine.medical_specialtyTime FactorsBlood PressureBioinformaticsRisk AssessmentBody Mass IndexRisk FactorsInternal medicinePrevalenceInternal MedicinemedicineHumansObesityProspective StudiesProportional Hazards ModelsMetabolic Syndromebusiness.industryAge Factorsnutritional and metabolic diseasesmedicine.diseaseHealth SurveysLipidsEndocrinologyCardiovascular DiseasesHypertensionHong KongMetabolic syndromebusinessAmerican Journal of Hypertension
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Virtual reality exposure-based therapy for the treatment of post-traumatic stress disorder: a review of its efficacy, the adequacy of the treatment p…

2015

Introduction The essential feature of post-traumatic stress disorder (PTSD) is the development of characteristic symptoms following exposure to one or more traumatic events. According to evidence-based intervention guidelines and empirical evidence, one of the most extensively researched and validated treatments for PTSD is prolonged exposure to traumatic events; however, exposure therapy can present some limitations. Virtual reality (VR) can help to improve prolonged exposure because it creates fictitious, safe, and controllable situations that can enhance emotional engagement and acceptance. Objective In addition to carrying out a review to evaluate the efficacy of VR exposure-based thera…

medicine.medical_specialtyTreatment protocolbusiness.industrymedicine.medical_treatmentExposure therapyTraumatic stressAlternative medicinePsychological interventionReviewVirtual realityBioinformaticsProlonged exposuretreatment efficacyIntervention (counseling)medicineprolonged exposureevidence-based interventionbusinessClinical psychology
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The lyon clinical olfactory test: validation and measurement of hyposmia and anosmia in healthy and diseased populations.

2011

 ; International audience; The LCOT is a self-administered test designed to assess olfactory deficits. Altogether, 525 subjects contributed to the validation. Elderly participants were well represented in this sample. In a validation study (study 1), 407 healthy and 17 anosmic volunteers between 15 and 91 years of age underwent threshold, supraliminal detection, and identification testing. Cutoff values for normosmia and hyposmia were calculated and applied in a second study in a group of patients with smell complaints and in a group of Alzheimer patients with age-matched controls. Incidence of smell deficit was estimated at 5.6% in the healthy population of study 1, and at 16% in the elder…

medicine.medical_specialtyValidation studyArticle SubjectOlfactory disorderAnosmialcsh:SurgeryMédecine humaine et pathologieOlfactionTest validityAudiologyBioinformaticsaging;development;olfaction;olfactory disorder;Alzheimer's disease;cognitive impairment03 medical and health sciences0302 clinical medicineHyposmiamedicineFood and Nutrition[SDV.MHEP.OS]Life Sciences [q-bio]/Human health and pathology/Sensory Organs030223 otorhinolaryngologyolfactory disorderdevelopmentcognitive impairmentbusiness.industryIncidence (epidemiology)Healthy populationaging[ SDV.SPEE ] Life Sciences [q-bio]/Santé publique et épidémiologielcsh:RD1-811Alzheimer's diseaselcsh:Otorhinolaryngologylcsh:RF1-547[SDV.MHEP.OS] Life Sciences [q-bio]/Human health and pathology/Sensory Organs[SDV.SPEE] Life Sciences [q-bio]/Santé publique et épidémiologie[ SDV.MHEP.OS ] Life Sciences [q-bio]/Human health and pathology/Sensory OrgansAlimentation et NutritionNeurosciences (Sciences cognitives)Human health and pathology[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologiemedicine.symptombusiness030217 neurology & neurosurgeryResearch ArticleNeuroscienceolfaction
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A tailored telephone and email based exercise intervention induced reductions in various measures of body composition in physically inactive adults: …

2018

Obesity prevalence has increased the past decades and has become a serious public health problem. The aim of this six-month assessor-blinded, parallel-group randomized controlled trial was to assess the effect of a tailored telephone and email-based exercise intervention on various measures of body composition in a sample of apparently healthy and physically inactive adults. A total of 111 volunteering adults (40–55 yr) in Southern Norway were randomly assigned to an intervention group (IG; n = 39) or a no-information control group (CG; n = 50), by random allocation numbering. The IG received feedback on their health-related physical fitness, information on guidelines and recommendations fo…

medicine.medical_specialtyWaistPhysical fitnesslcsh:Medicine030209 endocrinology & metabolismHealth InformaticsBody compositionlaw.invention03 medical and health sciences0302 clinical medicineRandomized controlled triallawIntervention (counseling)medicine030212 general & internal medicineCG Control GroupCRF cardiorespiratory fitnessbusiness.industryPublic healthWC Waist Circumferencelcsh:RWeight changeWeight changePublic Health Environmental and Occupational HealthRegular Articlemedicine.diseaseObesityIG Intervention GroupPhysical therapyFPskf Fat Percentage by skinfoldsBMI Body Mass IndexbusinessMixed delivery modesBody mass indexPreventive Medicine Reports
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