Search results for "init"
showing 10 items of 6629 documents
Modeling of intracellular transport in realistic cell geometries
2018
The transport of molecules inside cells is a complex process, the characterization of which is important to gain full understanding of cellular processes. Understanding of intracellular transport is also important for medical applications, for example when analyzing transport of medicine inside cells. The intracellular environment is very complex, and at least the most crucial parts of this complexity must be accounted for to solve transport problems in cells. In this thesis the results of studies in modeling intracellular transport are presented. The aim of the work was to model intracellular transport of proteins and viral capsids in realistic cell environments. To this end, microscopic m…
Du moins pour nous autres hommes. Intuition et finitude dans la Critique de la raison pure
2008
Performance analysis of the first Reverse Electrodialysis prototype plant operating with natural brackish water and salt pond brine
2014
Reverse Electrodialysis (RED) has gained a strong interest among the salinity gradient energy technologies during the last years. Recently, notable improvements have been reached in terms of membranes and stack performances using artificial solutions. However, the use of real saline solutions strongly affects the process performance, requiring additional R&D efforts for a successful scale-up of such technology. This work focuses on the experimental campaign performed on the first RED prototype plant fed with real brackish water and saltworks brine. The plant is located within the Ettore e Infersa saltworks in Marsala (TP, South of Italy). It is the final accomplishment of the REAPower proje…
Optimisation analysis of Reverse Electrodialysis systems for power production from concentrated brines
2016
Reverse Electrodialysis (RED) is rapidly growing as technology to produce electric energy by mixing saline solutions with different salinity. Recent developments have shown promising results on real site installations, demonstrating the feasibility of the RED process on the pilot scale. Therefore, further modelling efforts are now needed to optimise the technology, in order to enhance the performance. In this work, an optimisation study for the RED process is presented, taking into account saline waters and concentrated brine as feed streams. The model, which is developed within GAMS environment, predicts the optimal set of process variables that maximise the process yield, as well as the g…
The Photocycle of Bacteriophytochrome Is Initiated by Counterclockwise Chromophore Isomerization.
2022
Photoactivation of bacteriophytochrome involves a cis–trans photoisomerization of a biliverdin chromophore, but neither the precise sequence of events nor the direction of the isomerization is known. Here, we used nonadiabatic molecular dynamics simulations on the photosensory protein dimer to resolve the isomerization mechanism in atomic detail. In our simulations the photoisomerization of the D ring occurs in the counterclockwise direction. On a subpicosecond time scale, the photoexcited chromophore adopts a short-lived intermediate with a highly twisted configuration stabilized by an extended hydrogen-bonding network. Within tens of picoseconds, these hydrogen bonds break, allowing the c…
Complementary approaches for assessing protein sources in fish feed
2018
Fluctuating fishmeal (FM) prices and declining marine fish stocks have led to the current trend of replacing dietary FM with plant proteins (PP) in fish feed. PPs offer challenges both with respect to nutritional quality and the occurrence of antinutrients. The assessment of utilisation efficiency of PPs for growth is important for the sustainable production of fish feed. The overall aim of this thesis was to investigate the applicability of stable isotope analysis in combination with respirometry in the evaluation of dietary PPs for juvenile rainbow trout (Oncorhynchus mykiss). The dietary PPs were corn gluten meal (CGM), rapeseed protein concentrate (RPC) and potato protein (PoP). Complet…
Johtajasta tohtoriksi - osaajasta oppijaksi? : organisaatiossa oppimisen monta todellisuutta goffmanilaisena kehysanalyysina
2012
Step-by-step analysis of drinking water treatment trains using size-exclusion chromatography to fingerprint and track protein-like and humic/fulvic-l…
2019
This paper provides a glimpse into the removal of dissolved organic matter (DOM) during conventional drinking water treatment and evaluates the potential of high-performance size-exclusion chromatography (HPSEC) as a supplementary tool for routine monitoring of drinking water treatment plants (DWTPs). Two DWTPs in Central Finland were systematically evaluated using HPSEC with simultaneous UV and fluorescence detection. For tyrosine-like, tryptophan-like, and humic/fulvic-like DOM fractions of various molecular weight (MW) values, the total and step-by-step removal efficiencies were estimated along the treatment trains. Overall, both DWTPs removed ∼70% of dissolved organic carbon (DOC) and r…
Vieraslajin, komealupiinin (Lupinus polyphyllus), vaikutus koiranputken (Anthriscus sylvestris) kasvun allokointiin ja siemenpainoihin
2013
Vieraslajin leviäminen uudelle alueelle luo haasteita niin vieras- kuin paikalliselle lajille. Molempien lajien on sopeuduttava ja vastattava toistensa aiheuttamiin valintapaineisiin. Koska vieraslajit ovat monesti uudessa ympäristössä voimakkaita kilpailijoita, ja siten vaikuttavat muihin lajeihin sekä ympäristöönsä voimakkaasti ja jopa haitallisesti, on mahdollista, että vieraslajin kanssa esiintyvissä paikallisissa lajeissa on havaittavissa muutoksia niiden elinkiertopiirteissä. Vaikka kilpailun tiedetään olevan yksi merkittävimpiä valintapaineita, tietoa vieraslajien vaikutuksista yksittäisiin suomalaisiin lajeihin on vähän. Tutkimalla vieraslajin aiheuttamia evolutiivisia muutoksia pai…