Search results for "init"
showing 10 items of 6629 documents
Violenze “di genere” e violenze “sulle donne”: problemi di definizione e di rilevazione empirica
2020
Il capitolo punta a problematizzare gli aspetti definitori del concetto di “violenza di genere” e quelli legati più strettamente alla sua rilevazione/misurazione, cercando di fornire un contributo all’utilizzo delle statistiche sul tema in maniera avveduta e consapevole. The chapter aims to problematize the defining aspects of the concept of "gender violence" and those related more closely to its detection / measurement, trying to provide a contribution to the use of statistics on the subject in a prudent and conscious manner.
Mitochondrial function and sirtuin expression in hippocampus of young and old high- and low-capacity runner rats
2016
Introduction: Exercise and aerobic capacity are associated with improved learning in animals and humans. The hippocampus is a brain structure involved in learning and memory. High rates of neurogenesis have been shown to take place in the dental gyrus of hippocampus in response to physical exercise. It is not known whether mitochondrial dysfunction in the hippocampus is responsible for decline in cognitive function associated with low fitness level and aging, and whether intrinsic aerobic capacity is a risk factor for it. Methods: Mitochondrial function was investigated in the hippocampi of young and old highcapacity runner (HCR) and low-capacity runner (LCR) rats using high-performance res…
Teologia miłosierdzia Bożego według bulli Misericordiae vultus papieża Franciszka
2016
Pope Francis in the bull Misericordiae vultus encouraged to reflect on the meaning of God’s mercy in human history and the practice of Christian charity in life. According to the papal encouragement this article reflects on the content of the notion of God’s mercy. It focuses on these aspects which proved to be essential in the papal bull. The analyses performed are made from a theological perspective; they are therefore an attempt of interpretation, justification, and systematization of the content of the papal statements about mercy. They focus on three main themes present in the papal reflection: God’s mercy is being considered in trinitological, christological and ecclesiological aspect…
On the Finite Element Modeling of the Lumbar Spine: A Schematic Review
2023
Finite element modelling of the lumbar spine is a challenging problem. Lower back pain is among the most common pathologies in the global populations, owing to which the patient may need to undergo surgery. The latter may differ in nature and complexity because of spinal disease and patient contraindications (i.e., aging). Today, the understanding of spinal column biomechanics may lead to better comprehension of the disease progression as well as to the development of innovative therapeutic strategies. Better insight into the spine’s biomechanics would certainly guarantee an evolution of current device-based treatments. In this setting, the computational approach appears to be a remarkable …
Legacy system evolution - A comparative study of modernisation and replacement initiation factors
2007
Decisions regarding information system evolution strategy become topical as the organisation’s information systems age and start to approach the end of their life cycle. An interview study was conducted in order to compare factors influencing modernisation and replacement initiation. System age, obsolete technology and high operation or maintenance costs were identified as triggers for both modernisation and replacement projects. The results show that the most prevalent individual reason for modernisation initiative is business development. Common initiation factors for replacement projects were end of vendor support and system’s inability to respond to organisation’s business needs. peerRe…
Die Zauber-"Wintersaat". Ein Vergleich zwischen Thomas Manns "Zauberberg" und Wacław Berents "Wintersaat"
2020
The author carries out a comparative analysis of Wacław Berents “Winter Crop” (Ozimina) and Thomas Manns “The Magic Mountain” (Der Zauberberg). Although the two compared novels are of different historical and cultural backgrounds, she shows things that they have in common. The analysis does not concentrate on the interrelations that were realised at the time but on tracking down the sources of the two writers’ imagination, intellectual fascinations, disturbing similarities (and obvious differences) that led to building up the world they created and also in the finesse of their language. The author draws a map of “mental spurts”, “spiritual colouration” and early 20th century History echoing…
3He NMR: from free gas to its encapsulation in fullerene
2013
The 3He nuclear magnetic shieldings were calculated for single helium atom, its dimer, simple models of fullerene cages (He@Cn), and single wall carbon nanotubes. The performances of several levels of theory (HF, MP2, DFT-VSXC, CCSD, CCSD(T), and CCSDT) were tested. Two sets of polarization-consistent basis sets were used (pcS-n and aug-pcS-n), and an estimate of 3He nuclear magnetic shieldings in the complete basis set limit using a two-parameter fit was established. Theoretical 3He results reproduced accurately previously reported theoretical values for helium gas, dimer, and helium probe inside several fullerene cages. Excellent agreement with experimental values was achieved. 3He nuclea…
Suitability of MMGBSA for the selection of correct ligand binding modes from docking results
2019
The estimation of the correct binding mode and affinity of a ligand into a target protein using computational methods is challenging. However, docking can introduce poses from which the correct binding mode could be identified using other methods. Here, we analyzed the reliability of binding energy estimation using the molecular mechanics‐generalized Born surface area (MMGBSA) method without and with energy minimization to identify the likely ligand binding modes within docking results. MMGBSA workflow (a) outperformed docking in recognizing the correct binding modes of androgen receptor ligands and (b) improved the correlation coefficient of computational and experimental results of rescor…
Molekulārās sensibilizācijas profila pret suņiem saistība ar astmas un alerģiska rinīta kontroles rādītājiem
2022
Izpētes objekts Šis pētījums tika veikts, lai novērtētu suņa alergēnu molekulu sensitizāciju saistību ar astmu un alerģisko rinītu. Pētījuma metodoloģija Tika analizēti dati pacientiem, kuriem veikta ALEX vai ALEX2 paneļa testēšana un iegūts sensitizāciju profils katrai suņa alergēna molekulai (Can f 1, Can f 2, Can f 3, Can f 4, Can f 5 un Can f 6). Iegūtie dati tika analizēti kopā ar pacienta datiem par astmu un alerģisko rinītu. Rezultāti Molekulārā sensitizācija pret Can f 1, Can f 2 un Can f 6 uzrādīja statistiski nozīmīgu ietekmi uz astmas risku, taču, kad tika izslēgta sensitizācija pret citu dzīvnieku epitēliju, tikai Can f 1 un Can f 2 uzrādīja statistiski nozīmīgu ietekmi. Arī poz…
Functional Extrapolations to Tame Unbound Anions in Density-Functional Theory Calculations
2019
Standard flavors of density-functional theory (DFT) calculations are known to fail in describing anions, due to large self-interaction errors. The problem may be circumvented using localized basis sets of reduced size, leaving no variational flexibility for the extra electron to delocalize. Alternatively, a recent approach exploiting DFT evaluations of total energies on electronic densities optimized at the Hartree-Fock (HF) level has been reported, showing that the self-interaction-free HF densities are able to lead to an improved description of the additional electron, returning affinities in close agreement with the experiments. Nonetheless, such an approach can fail when the HF densitie…