Search results for "intensity"

showing 10 items of 1091 documents

Preliminary experience with the application of Gadolinium-DTPA before MR imaging-guided laser-induced interstitial thermotherapy of brain tumors

1997

The purpose of this study was to investigate the potential value of i.v. gadolinium-diethylenetriamine penta-acetic acid (Gd-DTPA) applied before MRI-guided laser-induced interstitial thermotherapy (LITT) of brain tumors without original enhancement, especially in defining total lesion size during therapy. MRI-guided LITT was performed on two patients with astrocytoma WHO II. For both patients, Gd-DTPA was administered intravenously after a first irradiation period and LITT was continued after pulling back the light guide to coagulate the upper parts of the tumor. In both patients, the whole irreversible damaged zone of the second irradiation period after Gd-DTPA showed an intense increase …

AdultGadolinium DTPAMalePathologymedicine.medical_specialtySpatial expansionGadoliniumchemistry.chemical_elementAstrocytomaDrug Administration ScheduleLesionGadolinium DTPAOrganometallic CompoundsmedicineHumansRadiology Nuclear Medicine and imagingBrain Neoplasmsbusiness.industryAstrocytomaLight guideHyperthermia InducedPentetic AcidImage Enhancementmedicine.diseaseMagnetic Resonance ImagingMr imagingchemistryFemaleLaser TherapySignal intensitymedicine.symptomNuclear medicinebusinessFollow-Up StudiesJournal of Magnetic Resonance Imaging
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3D TOF MR Angiography of Cerebral Arteriovenous Malformations after Radiosurgery

1993

To investigate the potential of three-dimensional time-of-flight MR angiography (MRA) to complement SE imaging, 18 patients with intracerebral arteriovenous malformations were prospectively followed after undergoing radiosurgery. Vessel occlusion after stereotaxic single high dose radiotherapy develops slowly. The MRA detected signs of nidus obliteration earlier and with a higher sensitivity than did SE imaging. Six months after radiosurgery, MRA showed a reduction of the nidus flow signals in nine patients and after 1 year it showed reduction in 15 of the 18 patients. As shown by MRA, the loss of flow signals was related to a reduction of the nidus size in 4 patients after 6 months and in …

AdultIntracranial Arteriovenous MalformationsMalemedicine.medical_specialtyAdolescentmedicine.medical_treatmentHemodynamicsRadiosurgeryRadiosurgerymedicineHumansRadiology Nuclear Medicine and imagingProspective StudiesChildCerebral Hemorrhagemedicine.diagnostic_testVascular diseasebusiness.industryArteriovenous malformationBlood flowCerebral ArteriesMiddle AgedImage Enhancementmedicine.diseaseCerebral VeinsMagnetic Resonance ImagingHyperintensityCerebral AngiographyCerebral blood flowRegional Blood FlowAngiographyFemaleRadiologyNuclear medicinebusinessFollow-Up StudiesJournal of Computer Assisted Tomography
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Impact of a 4-Week Intensified Endurance Training Intervention on Markers of Relative Energy Deficiency in Sport (RED-S) and Performance Among Well-T…

2020

Cyclists often apply block periodization to high training volumes in meso- and macrocycles to optimize training adaptation and to prepare for competition. Body mass influences performance in many sports, including endurance disciplines, and conditions related to the syndrome Relative Energy Deficiency in Sports (RED-S) such as metabolic adaptations and premature osteoporosis have also been reported in male cyclists. This study aimed to determine how a 4-week mesocycle of intensified endurance training designed to increase performance, would affect markers of RED-S in well-trained male cyclists. Twenty-two participants (age: 33.5 ± 6.6 years, height: 181.4 ± 5.2 cm, weight: 76.5 ± 7.4 kg, pe…

AdultMale0301 basic medicineVDP::Medisinske Fag: 700::Idrettsmedisinske fag: 850::Treningslære: 851Endocrinology Diabetes and Metabolismmale cyclistsOsteoporosisenergy availability030209 endocrinology & metabolismAthletic PerformanceHigh-Intensity Interval Traininglcsh:Diseases of the endocrine glands. Clinical endocrinologyhormonal responseInterval training03 medical and health sciencesEndocrinology0302 clinical medicineAnimal scienceEndurance trainingHumansRelative Energy Deficiency in SportMedicineProspective Studiesresting metabolic rateTestosteroneOriginal Researchlcsh:RC648-665Triiodothyroninebusiness.industryendurance athletesVO2 maxVDP::Medisinske Fag: 700::Idrettsmedisinske fag: 850medicine.diseaseEndurance Training030104 developmental biologytestosteroneBasal metabolic ratetraining interventionBasal MetabolismbusinessBiomarkersRelative energyFrontiers in Endocrinology
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The effect of amifostine or IMRT to preserve the parotid function after radiotherapy of the head and neck region measured by quantitative salivary gl…

2008

Purpose: In this retrospective study, two approaches to preserve the parotid function after radiotherapy (RT) were compared: application of the radioprotective agent amifostine during RT and parotid sparing intensity-modulated radiotherapy (IMRT). Patients and methods: Patients were qualified for this analysis if (1) both parotid glands received a radiation dose of P50 Gy using conventional radiotherapy techniques (cRT) or if they received a parotid sparing IMRT as alternative, if (2) salivary gland scintigraphies before and after RT were performed, and if (3) a normal parotid function was present before RT. Quantitative salivary gland scintigraphy was used to assess the parotid gland funct…

AdultMaleAdolescentmedicine.medical_treatmentRadiation-Protective AgentsRadiation DosageXerostomiaAmifostinestomatognathic systemSalivary gland scintigraphymedicineHumansParotid GlandRadiology Nuclear Medicine and imagingRadiation InjuriesRadionuclide ImagingHead and neckAgedRetrospective StudiesAged 80 and overSalivary glandbusiness.industryHead and neck cancerRetrospective cohort studyHematologyAmifostineMiddle Agedmedicine.diseaseParotid glandRadiation therapystomatognathic diseasesmedicine.anatomical_structureOncologyHead and Neck NeoplasmsFemaleRadiotherapy Intensity-ModulatedbusinessNuclear medicinemedicine.drugRadiotherapy and Oncology
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Age-related muscle activation profiles and joint stiffness regulation in repetitive hopping

2011

Abstract It is well documented that increasing effort during exercise is characterized by an increase in electromyographic activity of the relevant muscles. How aging influences this relationship is a matter of great interest. In the present study, nine young and 24 elderly subjects did repetitive hopping with maximal effort as well as with 50%, 65%, 75% and 90% intensities. During hopping joint kinematics were measured together with electromyographic activity (EMG) from the soleus, gastrocnemius medialis, gastrocnemius lateralis and tibialis anterior muscles. The results showed that agonist activation increased in both age groups with increasing intensity. The highest jumping efficiency (E…

AdultMaleAgonistAgingmedicine.medical_specialtymedicine.drug_classBiophysicsNeuroscience (miscellaneous)medicine.disease_causeStretch shortening cycleJumpingPhysical medicine and rehabilitationElastic ModulusmedicineHumansRange of Motion Articularta315Muscle SkeletalAgedAged 80 and overbusiness.industryMuscle activationMiddle AgedCoactivationIntensity (physics)medicine.anatomical_structureJoint stiffnessFemaleNeurology (clinical)medicine.symptomAnklebusinessAnkle JointLocomotionMuscle ContractionJournal of Electromyography and Kinesiology
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Evaluation of the apparent diffusion coefficient in patients with recurrent glioblastoma under treatment with bevacizumab with radiographic pseudores…

2017

Abstract Background Response Assessment in Neuro-Oncology Criteria (RANO), are used to asses response to first-line treatment of glioblastoma (GBM). Differentiation between response and pseudoresponse under treatment with Bevacizumab (BVZ) remains challenging. This study evaluates ADC changes in patients with radiographic pseudoresponse under treatment with (BVZ). Methods Patients (n = 40) with recurrent GBM under-treatment with BVZ underwent MRI before, two and four months after treatment with BVZ. In patients with radiological pseudoresponse (n = 11), ADC analyses were performed. Areas with decreasing T1 contrast enhancement (CE) and FLAIR signal decrease were manually selected and compar…

AdultMaleBevacizumabRadiographyPseudoresponseFluid-attenuated inversion recovery030218 nuclear medicine & medical imaging03 medical and health sciencesAntineoplastic Agents Immunological0302 clinical medicineImage Interpretation Computer-AssistedmedicineHumansEffective diffusion coefficientRadiology Nuclear Medicine and imagingIn patientAgedRadiological and Ultrasound TechnologyBrain Neoplasmsbusiness.industryMiddle Agedmedicine.diseaseHyperintensityBevacizumabbody regionsDiffusion Magnetic Resonance ImagingTreatment OutcomeFemaleNeurology (clinical)Neoplasm Recurrence LocalGlioblastomabusinessNuclear medicine030217 neurology & neurosurgerymedicine.drugGlioblastomaJournal of Neuroradiology
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Impact of relative dose intensity of oxaliplatin in adjuvant therapy among stage III colon cancer patients on early recurrence: a retrospective cohor…

2020

Abstract Background Oxaliplatin-based therapy with FOLFOX-4 or CAPOX administered over 6 months remains the standard adjuvant treatment for stage III colon cancer (CC) patients. However, many patients experience dose reduction or early termination of chemotherapy due to oxaliplatin toxicity, which may increase the risk of early recurrence. The objective of this study was to analyze the relationship between the relative dose intensity of oxaliplatin (RDI-O) and early recurrence among stage III CC patients. Methods The study included 365 patients treated at five oncology centers in Poland between 2000 and 2014. Survival analysis was performed using the Kaplan-Meier method. Univariate analysis…

AdultMaleCancer Researchmedicine.medical_specialtyColorectal cancerGastroenterology03 medical and health sciences0302 clinical medicineInternal medicineGeneticsAdjuvant therapyMedicineHumans030212 general & internal medicineRelative dose intensityRC254-282Survival analysisAgedNeoplasm StagingRetrospective StudiesAged 80 and overUnivariate analysisbusiness.industryCumulative doseProportional hazards modelNeoplasms. Tumors. Oncology. Including cancer and carcinogensRetrospective cohort studyMiddle Agedmedicine.diseaseCumulative doseOxaliplatinColon cancerAdjuvant chemotherapyOxaliplatinOncologyChemotherapy Adjuvant030220 oncology & carcinogenesisColonic NeoplasmsFemaleNeoplasm Recurrence Localbusinessmedicine.drugResearch Article
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Treatment of tension-type headache with articulatory and suboccipital soft tissue therapy: A double-blind, randomized, placebo-controlled clinical tr…

2013

This study researches the effectiveness of two manual therapy treatments focused on the suboccipital region for tension-type headache. A randomized double-blind clinical trial was conducted over a period of four weeks with a follow-up at one month. Eighty-four patients with a mean age of 39.7 years (SD 11.4) with tension-type headache were assigned to 4 groups which included the following manual therapy treatment: suboccipital soft tissue inhibition; occiput-atlas-axis global manipulation; combination of both techniques; and a control group. The primary assessment consisted of collecting socio-demographic data and headache characteristics in a one-month base period, data such as age, gender…

AdultMaleComplementary and Manual TherapySoft tissue therapymedicine.medical_specialtyAdolescentPhysical Therapy Sports Therapy and RehabilitationPlaceboDouble blindYoung AdultSex FactorsDouble-Blind MethodmedicineHumansPain ManagementTherapy Soft TissueAgedbusiness.industryTension-Type HeadacheRehabilitationAge FactorsPatient AcuitySoft tissueMiddle AgedMusculoskeletal ManipulationsSurgeryIntensity (physics)Clinical trialComplementary and alternative medicineFemaleHeadachesmedicine.symptomManual therapybusinessJournal of Bodywork and Movement Therapies
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The effects of post-awakening light exposure on the cortisol awakening response in healthy male individuals.

2019

Abstract Background It is assumed that the expression of the cortisol awakening response (CAR) is modulated by light exposure during the peri-awakening period. While initial evidence supports this principal effect, the specific role of the spectral composition of light (brightness and wavelength) is still incompletely understood. Method Two counterbalanced within-subject experiments were conducted in a standardized sleep laboratory setting to investigate the effect of light intensity (study I; two days: dim vs. bright light) and spectral composition (study II; three days: red vs. blue vs. green light) on the CAR. Across studies, light exposure was conducted for one-hour post-awakening and t…

AdultMaleCortisol awakening responseHydrocortisoneLightEndocrinology Diabetes and MetabolismPhysiology03 medical and health sciencesYoung Adult0302 clinical medicineEndocrinologyMedicineHumansWakefulnessSalivaBiological PsychiatrySpectral compositionLight exposureEndocrine and Autonomic Systemsbusiness.industrySleep laboratoryPhototherapyHealthy Volunteers030227 psychiatryCircadian RhythmPsychiatry and Mental healthLight intensitybusinessSleep030217 neurology & neurosurgeryBright lightPsychoneuroendocrinology
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Predicting the Unknown and the Unknowable. Are Anthropometric Measures and Fitness Profile Associated with the Outcome of a Simulated CrossFit® Compe…

2021

The main objective of this research was to find associations between the outcome of a simulated CrossFit® competition, anthropometric measures, and standardized fitness tests. Ten experienced male CrossFit® athletes (age 28.8 ± 3.5 years

AdultMaleFunctional trainingHealth Toxicology and MutagenesisPhysical fitnesslcsh:MedicineSquatBivariate analysisBench pressArticlehigh-intensity functional training03 medical and health sciences0302 clinical medicineStatisticsHumanscross-trainingMuscle Strength030212 general & internal medicineExerciseMathematicsCross-trainingbusiness.industrylcsh:RPublic Health Environmental and Occupational Health030229 sport sciencesAnthropometryTest (assessment)functional fitnessAthletesPhysical FitnessExercise TestathletebusinessperformanceInternational Journal of Environmental Research and Public Health
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