Search results for "interactions."
showing 10 items of 1865 documents
Vacuum local and global electromagnetic self-energies for a point-like and an extended field source
2013
We consider the electric and magnetic energy densities (or equivalently field fluctuations) in the space around a point-like field source in its ground state, after having subtracted the spatially uniform zero-point energy terms, and discuss the problem of their singular behavior at the source's position. We show that the assumption of a point-like source leads, for a simple Hamiltonian model of the interaction of the source with the electromagnetic radiation field, to a divergence of the renormalized electric and magnetic energy density at the position of the source. We analyze in detail the mathematical structure of such singularity in terms of a delta function and its derivatives. We als…
Measurement of CP asymmetry in D 0 → K - K + and D 0 → π - πdecays
2014
Time-integrated $CP$ asymmetries in $D^0$ decays to the final states $K^- K^+$ and $\pi^- \pi^+$ are measured using proton-proton collisions corresponding to $3\mathrm{\,fb}^{-1}$ of integrated luminosity collected at centre-of-mass energies of $7\mathrm{\,Te\kern -0.1em V}$ and $8\mathrm{\,Te\kern -0.1em V}$. The $D^0$ mesons are produced in semileptonic $b$-hadron decays, where the charge of the accompanying muon is used to determine the initial flavour of the charm meson. The difference in $CP$ asymmetries between the two final states is measured to be \begin{align} \Delta A_{CP} = A_{CP}(K^-K^+)-A_{CP}(\pi^-\pi^+) = (+0.14 \pm 0.16\mathrm{\,(stat)} \pm 0.08\mathrm{\,(syst)})\% \ . \nonu…
Hidden charm N and Delta resonances with heavy-quark symmetry
2013
A model is developed to describe odd-parity baryon resonances generated dynamically through a unitary baryon-meson coupled-channels approach. The scheme applies to channels with light- and/or heavy-quark content. Distinct features of the model are that i) the interaction is an S-wave contact one, ii) it reduces to the SU(3) Weinberg-Tomozawa Hamiltonian when light pseudoscalar mesons are involved, thus respecting chiral symmetry, iii) spin-flavor is preserved in the light-quark sector, and iv) heavy-quark spin symmetry is fulfilled in the heavy-quark sector. In particular, baryon-meson states with different content in c or in (c) over bar do not mix. The model is a minimal one and it contai…
Exploration of extracellular vesicles from Ascaris suum provides evidence of parasite–host cross talk
2019
The prevalent porcine helminth, Ascaris suum, compromises pig health and reduces farm productivity worldwide. The closely related human parasite, A. lumbricoides, infects more than 800 million people representing a disease burden of 1.31 million disability-adjusted life years. The infections are often chronic in nature, and the parasites have a profound ability to modulate their hosts' immune responses. This study provides the first in-depth characterisation of extracellular vesicles (EVs) from different developmental stages and body parts of A. suum and proposes the role of these vesicles in the host-parasite interplay. The release of EVs from the third- (L3) and fourth-stage (L4) larvae a…
Palaeogenomics of Upper Palaeolithic to Neolithic European hunter-gatherers
2023
Acknowledgements: The authors thank G. Marciani and O. Jöris for comments on archaeology; C. Jeong, M. Spyrou and K. Prüfer for comments on genetics; M. O’Reilly for graphical support for Fig. 5 and Extended Data Fig. 9; the entire IT and laboratory teams at the Department of Archaeogenetics of MPI-SHH for technical assistance; M. Meyer and S. Nagel for support with single-stranded library preparation; K. Post, P. van Es, J. Glimmerveen, M. Medendorp, M. Sier, S. Dikstra, M. Dikstra, R. van Eerden, D. Duineveld and A. Hoekman for providing access to human specimens from the North Sea (The Netherlands); M. D. Garralda and A. Estalrrich for providing access to human specimens from La Riera (S…
Regularized pseudopotential for mean-field calculations
2019
We present preliminary results obtained with a finite-range two-body pseudopotential complemented with zero-range spin-orbit and density-dependent terms. After discussing the penalty function used to adjust parameters, we discuss predictions for binding energies of spherical nuclei calculated at the mean-field level, and we compare them with those obtained using the standard Gogny D1S finite-range effective interaction.
Impacts of piscicide-induced fish removal on resource use and trophic diversity of lake invertebrates
2022
Chemical eradication of non-native species has become a widely used method to mitigate the potential negative im- pacts of altered competitive or predatory dynamics on biodiversity and natural ecosystem processes. However, the re- sponses of non-target species can vary from rapid full recovery to delayed or absent recolonization, and little is known about the potential shifts in resource use and trophic diversity of native species following chemical treatments. We used a before-after-control-impact approach to study the effects of rotenone piscicide treatment on abundance and tro- phic niche of benthic invertebrates in three untreated and three treated lakes in central Norway, the latter gr…
The intestinal 3M (microbiota, metabolism, metabolome) zeitgeist – from fundamentals to future challenges
2021
The role of the intestine in human health and disease has historically been neglected and was mostly attributed to digestive and absorptive functions. In the past two decades, however, discoveries related to human nutrition and intestinal host-microbe reciprocal interaction have established the essential role of intestinal health in the pathogenesis of chronic diseases and the overall wellbeing. That transfer of gut microbiota could be a means of disease phenotype transfer has revolutionized our understanding of chronic disease pathogenesis. This narrative review highlights the major concepts related to intestinal microbiota, metabolism, and metabolome (3M) that have facilitated our fundame…
A three-way perspective of stoichiometric changes on host–parasite interactions
2015
Changes in environmental nutrients play a crucial role in driving disease dynamics, but global patterns in nutrient-driven changes in disease are difficult to predict. In this paper we use ecological stoichiometry as a framework to review host–parasite interactions under changing nutrient ratios, focusing on three pathways: (i) altered host resistance and parasite virulence through host stoichiometry (ii) changed encounter or contact rates at population level, and (iii) changed host community structure. We predict that the outcome of nutrient changes on host–parasite interactions depends on which pathways are modified, and suggest that the outcome of infection could depend on the overlap in…
Effects of Anandamide and Noxious Heat on Intracellular Calcium Concentration in Nociceptive DRG Neurons of Rats
2007
As an endogenous agonist at the cannabinoid receptor CB1 and the capsaicin-receptor TRPV1, anandamide may exert both anti- and pronociceptive actions. Therefore we studied the effects of anandamide and other activators of both receptors on changes in free cytosolic calcium ([Ca2+]i) in acutely dissociated small dorsal root ganglion neurons (diameter: ≤30 μm). Anandamide (10 μM) increased [Ca2+]iin 76% of the neurons. The EC50was 7.41 μM, the Hill slope was 2.15 ± 0.43 (mean ± SE). This increase was blocked by the competitive TRPV1-antagonist capsazepine (10 μM) and in Ca2+-free extracellular solution. Neither exclusion of voltage-gated sodium channels nor additional blockade of voltage-gate…