Search results for "interference"
showing 10 items of 573 documents
Neuronal inhibition of the autophagy nucleation complex extends lifespan in post-reproductive C. elegans
2017
AbstractAutophagy is a ubiquitous catabolic process, which causes cellular bulk degradation of cytoplasmic components and thereby regulates cellular homeostasis. Inactivation of autophagy has been linked with detrimental effects to cells and organisms. The antagonistic pleiotropy theory postulates that fitness promoting genes during youth are harmful during aging (Williams 1957). On this basis we examined genes mediating post-reproductive longevity using an RNA interference screen. From this screen we identified 30 novel regulators of post-reproductive longevity including pha-4. Through downstream analysis of pha-4 we identify that genes governing the early stages of autophagy up until the …
The Causal Influence of Life Meaning on Weight and Shape Concerns in Women at Risk for Developing an Eating Disorder
2021
Background: Although previous studies have shown an inverse relation between life meaning and eating disorder symptoms, the correlational nature of this evidence precludes causal inferences. Therefore, this study used an experimental approach to test the causal impact of life meaning on individuals' weight and shape concerns.Methods: Female students at risk for developing an eating disorder (N = 128) were randomly assigned to the control or the meaning condition, which involved thinking about and committing to pursue intrinsically valued life goals. A color-naming interference task was used to assess the motivational salience of body-related stimuli, and self-report measures were used to as…
State-dependent foraging: lactating voles adjust their foraging behavior according to the presence of a potential nest predator and season
2015
Parental care often produces a trade-off between meeting nutritional demands of offspring and the duties of offspring protection, especially in altricial species. Parents have to leave their young unattended for foraging trips, during which nestlings are exposed to predators. We investigated how rodent mothers of altricial young respond to risk of nest predation in their foraging decisions. We studied foraging behavior of lactating bank voles (Myodes glareolus) exposed to a nest predator, the common shrew (Sorex araneus). We conducted the experiment in summer (high resource provisioning for both species) and autumn (less food available) in 12 replicates with fully crossed factors “shrew pre…
El fundamento liberal del derecho a la intimidad
2021
T: The right to privacy is configured as a ?retaining wall? against State interference into the private sphere of people?s life. Throughout this work we will try to expose the philosophical-liberal foundations that have led us to what is now conceived as the ?right to privacy?.
Ultraplānu anodizēta alumīnija oksīda saturošu daudzslāņu sistēmu iegūšana un optiskās īpašības
2015
Darba mērķis ir izveidot daudzslāņu sistēmas, kas satur anodētu alumīnija oksīdu, un raksturot to optiskās īpašības. Noteikts poru augšanas ātrums skābeņskābes un sērskābes elektrolītos. Analizēta membrānu biezuma, porainības, izmantotā metāla un putināšanas leņķa ietekme uz daudzslāņu sistēmas optiskajām īpašībām. Veikta paraugu kristalogrāfiskā analīze, raksturojot poru augšanu un sakārtotību dažādās kristalogrāfiskajās plaknēs. Izstrādātas metodes daudzslāņu sistēmas pārklāšanai ar fluorescentiem materiāliem.
Determination of one compound in the presence of a single interference. Linear absorbances method
1992
The paper exposes the theoretical and experimental principles of an analytical procedure for the determination of one compound in the presence of another with an overlapping absorption spectrum, without the need to use any standard solutions of the latter. The proposed method was applied to the determination of binary mixtures of known composition in order to assess its accuracy and precision.
Declarative verbal memory impairments in middle-aged women who are caregivers of offspring with autism spectrum disorders: The role of negative affec…
2015
Caring for offspring diagnosed with a chronic psychological disorder such as autism spectrum disorder (ASD) is used in research as a model of chronic stress. This chronic stress has been reported to have deleterious effects on caregivers' cognition, particularly in verbal declarative memory. Moreover, such cognitive decline may be mediated by testosterone (T) levels and negative affect, understood as depressive mood together with high anxiety and anger. This study aimed to compare declarative memory function in middle-aged women who were caregivers for individuals with ASD (n = 24; mean age = 45) and female controls (n = 22; mean age = 45), using a standardised memory test (Rey's Auditory V…
Segregation of areas related to visual working memory in the prefrontal cortex revealed by rTMS.
2002
The functional organization of working memory (WM) in the human prefrontal cortex remains unclear. Storage and processing functions might be segregated in ventral and dorsal areas of the prefrontal cortex, respectively. If so, storage functions might be spared, irrespective of informational domain, following damage or dysfunction in dorsolateral areas. Alternatively, WM and prefrontal function in general might be segregated according to informational domains (e.g. spatial versus object-based information). In the present study we used repetitive transcranial magnetic stimulation (rTMS) to directly test these competing hypotheses. We applied rTMS to transiently and selectively disrupt the fun…
Chronometry of parietal and prefrontal activations in verbal working memory revealed by transcranial magnetic stimulation.
2003
We explored the temporal dynamics of parietal and prefrontal cortex involvement in verbal working memory employing single-pulse transcranial magnetic stimulation (TMS). In six healthy volunteers the left or right inferior parietal and prefrontal cortex was stimulated with the aid of a frameless stereotactic system. TMS was applied at 10 different time points 140-500 ms into the delay period of a two-back verbal working memory task. A choice reaction task was used as a control task. Interference with task accuracy was induced by TMS earlier in the parietal cortex than in the prefrontal cortex and earlier over the right than the left hemisphere. This suggests a propagation of information flow…
Influence of stimulus color on the control of reaching-grasping movements.
2001
This kinematic study aimed to determine whether color is a stimulus property involved in the control of reaching-grasping movements. Subjects reached and grasped a target-object, located either on the right or on the left of the subject's midline. A distractor, placed along the subject's midline, could be randomly presented. The colors, i.e., both chromaticity (red and green stimuli were presented) and lightness, of the target and distractor were varied in experiment 1. Only stimulus lightness and only stimulus chromaticity were varied in experiments 2 and 3, respectively. In experiment 4 subjects matched with their thumb and index finger the size of the target-stimuli presented in experime…