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Relationship Between Cannabis Use and Erectile Dysfunction: A Systematic Review and Meta-Analysis

2019

Globally, there is increasing usage and legalization of cannabis. In addition to its reported therapeutic effects, cannabis has several health risks which are not clearly defined. Erectile dysfunction (ED) is the most common male sexual disorder and there are plausible mechanisms linking cannabis use to ED. No attempt has been made to collate the literature on this topic. The aim of this review was to summarize the prevalence and risk of ED in cannabis users compared to controls. A systematic review of major databases from inception to January 1, 2019, without language restriction, was undertaken to identify studies investigating cannabis use and presence of ED. The analysis compared the p…

Intravenous iron therapy in patients with heart failure. A double-edged sword

2013

We read with interest the article of Beck-da-Silva et al., who recently concluded that intravenous (IV) iron seems to be superior over oral supplementation for improving functional capacity of heart failure patients [1]. Irrespective of the study design, involving comparison of functional outcomes between two different means of iron supplementation, we raise some clinical issues about the rationale underlying this investigation. According to the data published by Beck-da-Silva et al., the modest number of patients (n = 23) enrolled in this multicenter investigation had moderate anemia (i.e., hemoglobin concentration comprised between 90 and 120 g/L) but no evidence of iron deficiency, which…

Zagrożenia bezpieczeństwa wewnętrznego Niemiec jako konsekwencja procesów imigracyjnych

2017

In the Federal Republic of Germany there is a visible growth of the importance of immigration policy, of the weight of the problem of integration/lack of integration of mi- grants with the German society is visible, and of the need for permanent monitoring of internal security threats and difficulties with their prevention and fighting them. Many researchers working on the internal security of Germany admit that the current threats are linked, by the majority of Germans, with the influx of immigrants to this country. The migrants are seen as a source of potential risks, dangers and internal conflicts. It might be argued that there is an undeniable correlation between migra tion and security…

Thrombolysis Followed by Apixaban for Massive Pulmonary Embolism and Free-floating Thrombus in Right Ventricle in a Patient with Breast Cancer

2018

Free-floating thrombus in the right ventricle, associated with a massive acute pulmonary embolism (PE), is a rare phenomenon. PE is an important clinical entity with considerable mortality despite advances in diagnosis and treatment. The prognosis of PE depends on right ventricular dysfunction, myocardial injury markers, and early treatment. In this report, we present the case of a 71-year-old woman with a history of breast cancer admitted to intensive care unit for PE complicated by syncope. Although our case may seem complex because it is not represented in the guidelines, the result was satisfactory and showed how treatment with new anticoagulants (in this case apixaban) after massive th…

THYROID DISORDERS

2012

External Assessors as “Reviewers” for Quality Assurance of Open Access Journals

2017

Sense experience and differentiation : Husserl on bodily awareness

2023

This article outlines the basic ingredients of Husserl’s theory of bodily awareness. It first analyses the concepts of hyletic and kinesthetic sensibility, and illustrates the interwovenness and equiprimordiality of Me and not-Me in Husserl’s account. Second, it shows how the concept of the lived body emerges from this complex sensible foundation. Thirdly, it argues that, as the area of intersection between the Me and the not-Me, bodily awareness is the initial locus of differentiation between Me and not-Me: an area where the experiential distinction between the Me and the not-Me is constantly negotiated. peerReviewed

Sounding Together: Family-Centered Music Therapy as Facilitator for Parental Singing During Skin-to-Skin Contact

2017

Introduction: When it comes to the delicate relationship between a baby and its parents, the voices of the parents have a significant role in communicating love, tenderness, and closeness as well as in supporting self-regulation as necessary for secure attachment. Under suboptimal experiences, such as premature birth, infant-directed singing takes on an even more important and therapeutic role since preterm infants miss the finely attuned auditory stimulation of the womb and the mother-infant dyad is disrupted too early.

Modified Glasgow Prognostic Score is Associated With Risk of Recurrence in Bladder Cancer Patients After Radical Cystectomy

2015

Recently, many studies explored the role of inflammation parameters in the prognosis of urinary cancers, but the results were not consistent. The modified Glasgow Prognostic Score (mGPS), a systemic inflammation marker, is a prognostic marker in various types of cancers. The aim of the present study was to investigate the usefulness of the preoperative mGPS as predictor of recurrence-free (RFS), overall (OS), and cancer-specific (CSS) survivals in a large cohort of urothelial bladder cancer (UBC) patients.A total of 1037 patients with UBC were included in this study with a median follow-up of 22 months (range 3-60 months). An mGPS = 0 was observed in 646 patients (62.3%), mGPS = 1 in 297 pa…

The CANNA-TICS Study Protocol: A Randomized Multi-Center Double-Blind Placebo Controlled Trial to Demonstrate the Efficacy and Safety of Nabiximols i…

2020

Background: Gilles de la Tourette syndrome (TS) is a chronic neuropsychiatric disorder characterized by motor and vocal tics. First-line treatments for tics are antipsychotics and tic-specific behavioral therapies. However, due to a lack of trained therapists and adverse events of antipsychotic medication many patients seek alternative treatment options including cannabis. Based on the favorable results obtained from case studies on different cannabis-based medicines as well as two small randomized controlled trials using delta-9-tetrahydrocannabinol (THC), we hypothesize that the cannabis extract nabiximols can be regarded as a promising new and safe treatment strategy in TS.Objective: To …