Search results for "interpretatio"
showing 10 items of 1068 documents
Living with an adult family member using advanced medical technology at home
2011
Living with an adult family member using advanced medical technology at home An increased number of chronically ill adults perform self-care while using different sorts of advanced medical technology at home. This hermeneutical study aimed to gain a deeper understanding of the meaning of living with an adult family member using advanced medical technology at home. Eleven next of kin to adults performing self-care at home, either using long-term oxygen from a cylinder or ventilator, or performing peritoneal or haemodialysis, were interviewed. The qualitative interviews were analysed using a Gadamerian methodology. The main interpretation explained the meaning as rhythmical patterns of connec…
The Relativity of Knowledge
2020
The three central themes of epistemological relativism are the relativity of truth, knowledge and reality. In the previous chapter, I demonstrated how the relativity of truth could be given a well-founded formulation by setting truth claims in relation to context and points of view—without renouncing the concept of an objective truth. In this chapter, I will examine the relativity of knowledge in regard to justifying it. The traditional theory of knowledge is individualistic, while viewpoint relativism leads to communal epistemology, where knowing is always in relation to a community. I will begin my analysis from the classical concept of knowledge, which can be considered the basic definit…
Role of the vomeronasal system in intersexual attraction in female mice
2008
Although it is generally accepted that rodents' sociosexual behavior relies mainly on chemosignals, the specific roles played by the vomeronasal and olfactory systems in detecting these signals are presently unclear. This work reports the results of three experiments aimed at clarifying the role of the vomeronasal system on gender recognition and intersexual attraction, by analyzing the effects of lesions of the accessory olfactory bulbs (AOB) in chemically naive female mice. The first experiment demonstrates that lesions of the AOB abolish the preference that females show for male-soiled bedding in tests in which the females can contact the bedding, thus having access to both volatile and …
A monoamine oxidase B gene variant and short-term antidepressant treatment response.
2007
Genetic differences among patients suffering from Major Depression are likely to contribute to interindividual differences in medication treatment response. Thus, the identification of gene variants affecting drug response is needed in order to be able to predict response to psychopharmacological drugs. This study analyzed a possible association of the common A644G single nucleotide polymorphism (SNP) within intron 13 of the monoamine oxidase B (MAOB) gene with antidepressant treatment response. The study population consisted of n = 102 patients with major depression (criteria of the Diagnostic and Statistical Manual of Mental Disorders, 4th Edition; DSM-IV) participating in a randomized do…
Surrogate endpoints for overall survival in digestive oncology trials: which candidates? A questionnaires survey among clinicians and methodologists
2010
Abstract Background Overall survival (OS) is the gold standard for the demonstration of a clinical benefit in cancer trials. Replacement of OS by a surrogate endpoint allows to reduce trial duration. To date, few surrogate endpoints have been validated in digestive oncology. The aim of this study was to draw up an ordered list of potential surrogate endpoints for OS in digestive cancer trials, by way of a survey among clinicians and methodologists. Secondary objective was to obtain their opinion on surrogacy and quality of life (QoL). Methods In 2007 and 2008, self administered sequential questionnaires were sent to a panel of French clinicians and methodologists involved in the conduct of …
Radiomic analysis reveals DCE-MRI features for prediction of molecular subtypes of breast cancer.
2017
The purpose of this study was to investigate the role of features derived from breast dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) and to incorporated clinical information to predict the molecular subtypes of breast cancer. In particular, 60 breast cancers with the following four molecular subtypes were analyzed: luminal A, luminal B, human epidermal growth factor receptor-2 (HER2)-over-expressing and basal-like. The breast region was segmented and the suspicious tumor was depicted on sequentially scanned MR images from each case. In total, 90 features were obtained, including 88 imaging features related to morphology and texture as well as dynamic features from tumor and …
The Probability Law for Generic Density Operators
2020
In this chapter, the probability law of the non-null eigenstates of a generic density operator—studied in the previous chapter—is determined, by showing that given the composite system and the subsystem being considered, a mapping arises which associates a universal probability distribution to the non-null eigenstates of the generic density operator. We thus recover the Born statistical interpretation without having assumed it as a postulate.
Statistical analysis when dealing with astigmatism: assessment of different spherocylindrical notations.
2001
Ophthalmic epidemiological studies frequently deal with ocular refractive errors, which are commonly expressed in the form sphere/cylinder x axis. However, this representation has been shown not to be the most suitable one for performing statistical analysis. Although alternative analytical and graphic methods to represent this kind of data have been developed, these formalisms have often gone unnoticed by researchers, despite their usefulness and versatility. Besides, there has been no discussion of how each of them fits in with a particular type of study. In this paper, several mathematical representations of dioptric power are revisited in a comprehensive way. The aim is to encourage res…
Symbolic leadership culture and its subcultures in one unified comprehensive school in Finland
2014
Purpose – The purpose of this paper is to describe a symbolic-interpretative research on the leadership culture and its subcultures in one unified comprehensive school in Finland. Design/methodology/approach – The research is a phenomenological, qualitative case study. Its methodology is based on triangulation. Findings – The leadership culture of the unified comprehensive school studied in the present research seemed to be based on equality, communality, appreciation, flow of information and humor. Besides examining the general leadership culture of the school, an attempt was made to study the possible subcultures of the school by examining the six subject groups into which the teachers w…
Knowledge construction about port performance evaluation: An international literature analysis
2017
Purpose: This study aims to identify and analyze the characteristics of international scientific research that addresses the segment of literature referring to port performance evaluation, in order to identify the existence of a theoretical alignment between the concept of performance evaluation, as an area of knowledge, and the practical application of port performance evaluation. Design/methodology: For the approach to the problem, this paper makes use of qualitative research, analyzing bibliographical portfolio characteristics related to port performance evaluation. An action research strategy was adopted, according to which the authors selected the bibliographical portfolio based on ana…