Search results for "interval"

Falls, Cognitive Function, and Balance Profiles of Singapore Community-Dwelling Elderly Individuals : Key Risk Factors

2017

Objective: This study compared occurrence of falls, cognitive function, and balance profiles across participants in elderly age categories, investigating associations between the 3 aspects in a sample of Singapore’s elderly population. Method: Community-dwelling elderly individuals (N = 385) were randomly recruited and grouped into “young-old (65-74 years),” “medium-old (75-84 years),” and “oldest-old (above 85 years)” groups. The Fallproof Health and Activity questionnaire, adapted Mini-Mental State Examination (MMSE), and Berg Balance Scale (BBS) tests were used to survey information related to falls, cognition, and balance profiles. Results: Findings revealed significant differences in M…

Conodont association of the Bashkirian-Moscovian boundary interval of the Donets Basin, Ukraine

2018

Ten sections spanning the Bashkirian-Moscovian boundary interval were studied in the Donets Basin. Six of them contain most representative conodont and foraminifer associations. In this paper we focused on three the most complete sections that include stratigraphically important conodont species, which belong to the Declinognathodus, Idiognathoides, Idiognathodus, Neognathodus, “Streptognathodus”, Mesogondolella and Diplognathodus genera. The majority of those species are widely distributed, which makes the correlation to other areas reliable. Two biotic events in conodont evolution were discovered in these sections. Two conodont lineages established here are considered as potential markers…

Everolimus With Reduced Tacrolimus Improves Renal Function in De Novo Liver Transplant Recipients: A Randomized Controlled Trial

2012

    In a prospective, multicenter, open-label study, de novo liver transplant patients were randomized at day 30±5 to (i) everolimus initiation with tacrolimus elimination (TAC Elimination) (ii) everolimus initiation with reduced-exposure tacrolimus (EVR+Reduced TAC) or (iii) standard-exposure tacrolimus (TAC Control). Randomization to TAC Elimination was terminated prematurely due to a higher rate of treated biopsy-proven acute rejection (tBPAR). EVR+Reduced TAC was noninferior to TAC Control for the primary efficacy endpoint (tBPAR, graft loss or death at 12 months posttransplantation): 6.7% versus 9.7% (-3.0%; 95% CI -8.7, 2.6%; p<0.001 for noninferiority [12% margin]). tBPAR occurred in…

Two Reflected Gray Code-Based Orders on Some Restricted Growth Sequences

2014

We consider two order relations: that induced by the m-ary reflected Gray code and a suffix partitioned variation of it. We show that both of them when applied to some sets of restricted growth sequences still yield Gray codes. These sets of sequences are: subexcedant and ascent sequences, restricted growth functions and staircase words. In particular, we give the first suffix partitioned Gray codes for restricted growth f unctions and ascent sequences; these latter sequences code various combinatorial classes as interval orders, upper triangular matrices without zero rows and zero columns whose non-negative integer entries sum up to n, and certain pattern-avoiding permutations. For each Gr…

No major role for periconceptional folic acid use and its interaction with theMTHFR C677Tpolymorphism in the etiology of congenital anorectal malform…

2014

Background: Both genetic and nongenetic factors are suggested to be involved in the etiology of congenital anorectal malformations (ARM). Maternal periconceptional use of folic acid supplements were inconsistently suggested to play a role in the prevention of ARM. Therefore, we investigated independent associations and interactions of maternal periconceptional folic acid supplement use and the infant and maternal MTHFR (methylenetetrahydrofolate reductase) C677T polymorphisms with the risk of ARM and subgroups of ARM. Methods: A case-control study was conducted among 371 nonsyndromic ARM cases and 714 population-based controls born between 1990 and 2012 using maternal questionnaires and DNA…

Retreatment with interferon plus ribavirin of chronic hepatitis C non-responders to interferon monotherapy: a meta-analysis of individual patient dat…

2002

Background and aims: Retreatment with a combination of α interferon (IFN) plus ribavirin of patients with chronic hepatitis C who did not respond to IFN monotherapy has not been assessed in large controlled studies. Methods: To assess the effectiveness and tolerability of IFN/ribavirin retreatment of non-responders to IFN and to identify predictors of complete (biochemical and virological) sustained response, we performed a meta-analysis of individual data on 581 patients from 10 centres. Retreatment with various IFN schedules (mean total dose 544 mega units) and a fixed ribavirin dose (1000–1200 mg/daily depending on body weight) was given for 24–60 (mean 39.5) weeks. Results: Biochemical …

Verenpaine hallintaan pienellä panostuksella?

2022

Prevalence and 30-Day Mortality in Hospitalized Patients With Covid-19 and Prior Lung Diseases.

2021

Patients with pre-existing respiratory diseases in the setting of COVID-19 may have a greater risk of severe complications and even death.A retrospective, multicenter, cohort study with 5847 COVID-19 patients admitted to hospitals. Patients were separated in two groups, with/without previous lung disease. Evaluation of factors associated with survival and secondary composite end-point such as ICU admission and respiratory support, were explored.1,271 patients (22%) had a previous lung disease, mostly COPD. All-cause mortality occurred in 376 patients with lung disease (29.5%) and in 819 patients without (17.9%) (Previous lung disease is a risk factor for mortality in patients with COVID-19.…

Coverage intervals for trace elements in human scalp hair are site and also gender-specific

2015

Hair analysis is a powerful tool for assessing human exposure to metals and metalloids (MM). The basis for interpreting laboratory results lie on the use of coverage intervals (CI), computed between the 0.025 and 0.975 fractiles, from a well-defined group of reference individuals reflecting normal and healthy people. A critical point in efficient use of CI, when used for comparative decision-making processes, forensic and clinic considerations, is constituted by confounding factors as the specific living site of study population and gender of participants. Our study aims to demonstrate that hair levels of trace elements are site specific and also gender specific. We have taken into account …

The Relationship Between Internalized Homophobia and Intimate Partner Violence in Same-Sex Relationships: A Meta-Analysis

2018

A meta-analysis was conducted to investigate the association between internalized homophobia and intimate partner violence (IPV) perpetration and victimization in same-sex relationships. The literature search and the application of the inclusion criteria made it possible to identify 10 studies, 2 of which were excluded due to missing data. Therefore, eight studies were finally included in the meta-analysis. The results showed positive and statistically significant associations between internalized homophobia and IPV perpetration and victimization, indicating that higher levels of internalized homophobia were related to higher levels of IPV. Specifically, the pooled effect size for the relat…