Search results for "interventio"
showing 10 items of 3167 documents
The Fight Against Organized Crime. Amid Contrasting Strategies and Respect for Human Rights
2012
Regulatory interventions and the application of lessons from outcomes together with the renewed value of human rights in criminal proceedings demonstrate that the fight against organized crime at the European level requires constant attention to the balance between individual rights on the one hand and the need for an effective investigation on the other.
Jean Itard en clave de educación inclusiva
2016
Jean Itard ha sido valorado tradicionalmente como el padre de la Educación Especial. Un análisis de sus Informes de 1801 y 1807 sobre la educación de Víctor, el joven salvaje de L’Aveyron desde la perspectiva de la Educación Inclusiva permite descubrir en él algunos rasgos significativos que ayudan a considerarlo como un claro precursor de ésta. Tales son: su reivindicación del derecho a la educación de los más desfavorecidos y la aplicación de un programa de formación integral, así como de un plan de rehabilitación individualizado a partir de las capacidades, limitaciones, necesidades y aspiraciones del alumno. Sus aportaciones metodológicas adelantan algunas de las propuestas actuales d…
Re-build landscape. Design for the reuse of abandoned quarries
2021
Looking at the history of our geological and mining heritage, we can see the evolution of the role played by underground mining sites over the centuries. However, if the activity of quarrying stones is as old as the presence of humans on earth, the issue of the territorial regeneration, based on the recovery and re-functionalization of abandoned quarries, is one of the central arguments of the contemporary debate. The extractive activity that on one hand constitutes an important economic resource for numerous territories, on the other hand requires particular attention to the environmental impact it causes. The theme is that of the so-called drosscapes, soils and residual spaces, once margi…
Positive Communities: Dimensions for Assessment and Intervention
2014
This chapter presents the construction of dimensions to assess people’s satisfaction with life in the community and makes a proposal to identify positive communities for future assessments. In the first place, this chapter provides a definition of the concepts related to a positive community and additionally, identifies the elements which people value in community life. Satisfaction with life in the community implies a personal perception of the degree of satisfaction in relation with different aspects of community life: community equipment, social services (health, education), public policies, public transportation, safety on the streets and in public places, housing, employment opportunit…
Breaking Stereotypes Concerning Remigrated Children - A Multinational Possible Intervention Plan through School
2021
The article is based on a multinational study involving five countries (Romania, Portugal, Italy, North Macedonia, and Iceland) facing the return migration or remigration situation. Pupils (n = 1615), teachers (n = 370), future teachers (n = 166) and youth workers (n = 30) were questioned about various aspects regarding the subject. Among the matters, cultural needs appear to the most important. Based on the statistical analysis, the article describes the dynamics of the dependent variables, with highlighted interest on cultural needs. Psychological and social needs, cultural needs, and educational needs are discussed and link conclusions appear. Following the analysis, an intervention plan…
Endothelin-1-Mediated Drug Resistance in EGFR-Mutant Non-Small Cell Lung Carcinoma.
2020
Abstract Progression on therapy in non-small cell lung carcinoma (NSCLC) is often evaluated radiographically, however, image-based evaluation of said therapies may not distinguish disease progression due to intrinsic tumor drug resistance or inefficient tumor penetration of the drugs. Here we report that the inhibition of mutated EGFR promotes the secretion of a potent vasoconstrictor, endothelin-1 (EDN1), which continues to increase as the cells become resistant with a mesenchymal phenotype. As EDN1 and its receptor (EDNR) is linked to cancer progression, EDNR-antagonists have been evaluated in several clinical trials with disappointing results. These trials were based on a hypothesis that…
Capillary enlargement, not sprouting angiogenesis, determines beneficial therapeutic effects and side effects of angiogenic gene therapy.
2010
Aims Currently, it is still unclear which mechanisms drive metabolic benefits after angiogenic gene therapy. The side-effect profile of efficient angiogenic gene therapy is also currently incompletely understood. In this study, the effects of increasing doses of adenoviral (Ad) vascular endothelial growth factor-A (VEGF-A) were evaluated on vascular growth, metabolic benefits, and systemic side effects. Methods and results Adenoviral vascular endothelial growth factor-A or AdLacZ control was injected intramuscularly (109–1011 vp/mL) or intra-arterially (5 × 1011 vp/mL) into rabbit ( n = 102) hindlimb muscles and examined 6 or 14 days later. Blood flow, tissue oedema, metabolic benefits, and…
The effects of a 2-year physical activity and dietary intervention on plasma lipid concentrations in children: the PANIC Study
2020
Funder: Opetus- ja Kulttuuriministeriö; doi: http://dx.doi.org/10.13039/501100003126
La eficacia de una intervención con aplicación móvil sobre actitudes asociadas a la violencia de pareja en los adolescentes de centros de acogida
2020
ABSTRACT This study focuses on the effectiveness of an app-based, monitored intervention using the Liad@s app in a residential youth-care setting. The aim of this intervention is to reduce maladaptive beliefs and attitudes linked to dating violence: distortions or myths about romantic love and hostile and benevolent dimensions of sexism. A quasi-experimental pre-post study with a control group was carried out. Participants were 71 adolescents from 9 group homes in Valencia (Spain). The outcomes measures were hostile and benevolent sexism (Ambivalent Sexism Inventory - ASI), ambivalence and prejudice towards men (Ambivalence toward Men Inventory - AMI), and myths about romantic love. The res…
Mental health and psychosocial support strategies in highly contagious emerging disease outbreaks of substantial public concern: A systematic scoping…
2021
Background Acute disease outbreaks such as the COVID-19 pandemic cause a high burden of psychological distress in people worldwide. Interventions to enable people to better cope with such distress should be based on the best available evidence. We therefore performed a scoping review to systematically identify and summarize the available literature of interventions that target the distress of people in the face of highly contagious disease outbreaks. Methods MEDLINE, Cochrane CENTRAL, Web of Science (January 2000 to May 7, 2020), and reference lists were systematically searched and screened by two independent reviewers. Quantitative and qualitative studies investigating the effects of psyc…