Search results for "invasive"

Sentinel-node biopsy in early stage ovarian cancer: a prospective multicentre study (SELLY)

2019

BackgroundSystematic para-aortic and bilateral pelvic lymphadenectomy is included in the standard comprehensive surgical staging in presumed early epithelial ovarian cancer. No prospective randomized evidence suggests it has potential therapeutic value, and related morbidity is not negligible.Primary Objective(s)To assess sensitivity, safety, and feasibility of the sentinel lymph node technique in identifying the presence of lymph node metastases in patients with early stage epithelial ovarian cancer.Study HypothesisSentinel lymph node detection with indocyanine green can accurately predict nodal status in a cohort of women with early stage epithelial ovarian cancer.Trial DesignThe SELLY tr…

Biochemical biomarkers of NAFLD/NASH

2020

Nonalcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease in the Western world and the global epidemics of obesity and type 2 diabetes have led to a dramatic increase of its prevalence and incidence. Among NAFLD patients, those with nonalcoholic steatohepatitis (NASH) have a double risk of fibrosis progression, that is the main driver toward the evolution in cirrhosis and its complications, including hepatocellular carcinoma and hepatic decompensation. Furthermore, patients with NAFLD are also at risk for cardiovascular diseases and extrahepatic malignancies, that represent the first and the second cause of death, respectively. The availability of non-invasi…

ONE-TROCAR VIDEO-ASSISTED STRIPPING TECHNIQUE FOR USE IN THE TREATMENT OF LARGE OVARIAN CYSTS IN INFANTS

2010

Abstract Background Management of ovarian cysts in infants is controversial; it can be conservative or surgical, and the management is determined by the cyst's size and sonographic features. Methods A surgical approach using a 10-mm umbilically placed operative laparoscope was taken in 3 female infants with antenatally diagnosed large, simple ovarian cysts. The contents of the cysts were partially aspirated and the cyst walls were stripped off the remaining ovarian parenchyma. No intraoperative or postoperative complications were recorded. Conclusions The one-trocar video-assisted stripping technique for large ovarian cysts in infants appears to be an ovarian-tissue-preserving procedure, an…

Real-Time Augmented Reality for Ear Surgery

2018

International audience; Transtympanic procedures aim at accessing the middle ear structures through a puncture in the tympanic membrane. They require visualization of middle ear structures behind the eardrum. Up to now, this is provided by an oto endoscope. This work focused on implementing a real-time augmented reality based system for robotic-assisted transtympanic surgery. A preoperative computed tomography scan is combined with the surgical video of the tympanic membrane in order to visualize the ossciles and labyrinthine windows which are concealed behind the opaque tympanic membrane. The study was conducted on 5 artificial and 4 cadaveric temporal bones. Initially, a homography framew…

Non-invasive LED-based screening solution for skin cancer

2019

Skin cancer is the most common type of malignant tumors in humans. Early diagnosis is the key to successful surgical treatment. In this work we present a non-invasive screening tool for early stage detection of skin cancer and also for the evaluation of post-operative scars.

Acute Hypoxemic Respiratory Failure in Immunocompromised Patients: Taking Aggressive Measures to Identify Etiology

2019

Poincaré surface profile. Novel non-invasive method to detect preferential ventricular response during atrial fibrillation

2007

The strategy of rate control during atrial fibrillation (AF) essentially deals with efforts to utilize and adjust the filtering properties of the atrioventricular (AV) node, allowing AF to continue and ensure that ventricular rate is controlled. In this work, a new tool based on the 3D Poincare plots is developed for the characterization of the ventricular response (VR) and the clinical evaluation of rate control therapies. Mechanisms underlying atrioventricular conduction during AF remain unclear. The role of the dual pathway AV nodal electrophysiology and the effects of the AV node modifications are still being an incognita. RR interval clusters exhibiting harmonic behaviour have been qua…

Image-Guided Mini-Invasive Treatments for Vascular and Oncologic Diseases: Embolization Therapy

2020

Transcatheter Embolization, also called Embolotherapy, is a mini-invasive, non-surgical therapeutic solution used in Interventional Radiology to close blood vessels deliberately. A wide range of embolic agents is available in clinical practice, including metal coils and liquid agents. More recent advances in biomaterials such as shape-memory foam and in-situ gelling solutions have led to the development of new pre-clinical embolic agents. This review offers a brief overview of current and emerging technologies in the field of endovascular embolization. The focus is on devices, materials and techniques.

Tips and tricks in office hysteroscopy

2015

Abstract Office hysteroscopy is a minimally invasive procedure that has been shown to be highly accurate in diagnosing abnormalities of the endometrial cavity and the endocervical canal. It allows the direct visualizing of uterine pathology without the need for general anesthesia and the use of an operating room, generating cost savings and greater compliance among patients. The advent of small-diameter hysteroscopes, the use of saline solution as a distension media, as well as the vaginoscopic technique have widely contributed to the diffusion of this technique worldwide, and currently it can be considered the gold standard for the examination of the uterine cavity. The improved technology…

Minimally invasive techniques in the treatment of saphenous varicose veins.

2008

Lower extremity venous insufficiency is common and increases with age. In addition to classical symptoms, it may result in skin changes and venous ulcers. Chronic venous insufficiency has a great impact on patients' health-related quality of life and is associated with considerable health care costs. Surgical ligation Of the junction with or without stripping has been the standard of care in the treatment of insufficient great and small saphenous veins. However, the recurrence rates are relatively high and surgery may be associated with serious adverse events and considerable down time; it is also cosmetically Suboptimal. To improve efficacy, patients' health-related quality of life and tre…