Search results for "istologia"

showing 10 items of 140 documents

Gli Arti

2009

Traduzione del cap. 16, dal Keith Moore e Persaud, sugli stati iniziali e finali dello sviluppo degli arti.

Settore BIO/17 - IstologiaArti Sviluppo
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Expression of β-Endorphin and Caspase-9 in Orthodontically Treated Dental Pulp.

2009

Introduction. For several years, our histology laboratory has worked in co-operation with the Winchmore Hill Dental Practice studying the activity of Acetylcholinesterase and some neuropeptides (CGRP, Sub. P, Enkephalins, Endorphins)(1) in orthodontic treated human dental pulp to clarify force's action. It seems that recent data do not yet, fully elucidate the exact effects of the force applied on teeth. For this reason we are investigating whether the traction is involved in some cases of pulpal death. In this study we focused on the expression of Caspase-9 and β-Endorphine. Materials and Methods. The expression of the 2 peptides has been identified through immunohistochemistry assay: not …

Settore BIO/17 - IstologiaB-endorphin Caspase-9 dental pulp
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B-Endorphin in Human Dental Pulp During Orthodontic Treatments

2008

Settore BIO/17 - IstologiaB-endorphin Human dental Pulp Orthodontic Treatment
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Orthodontic Stress BCL-2 Nodulation and Human Odontoblast's Survival

2013

Settore BIO/17 - IstologiaBcl-2 Caspase 9 Odontoblasts
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CB1 receptor expression in pancreatic islet of the obese and diabetes Zucher rats

2011

Settore BIO/17 - IstologiaCB1 receptorPancreaObesityZucker ratImmunohistochemistry
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Immunohistochemical and molecular expression of CB1 receptors in human colonic segment. Preliminary results

2011

Recent studies document that CB1 cannabinoid receptors, considered since its first identification as “brain specific”, could be expressed by peripheral tissues targets (adipose organs, enteric nervous system, striated muscle, epatocytes). This receptors were found in the GI tract of different species, including mice, rats, guinea pigs, pigs and humans. Endocannabinoids play a role in the pathophysiology of the gastrointestinal tract. They play a role in emesis, acid-related disorders, motility-related disorders, irritable bowel syndrome and diarrhea, and in inflammatory bowel disease. Endocannabinoid system might be involved in cancer differentiation, growth and cell migration. Distribution…

Settore BIO/17 - IstologiaCB1 Colonic segment cannabinoid
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Effect of chronic treatment with CB1 receptor antagonist (Rimonabant) on B-cells apoptosis in the pancreas of obese Zucker rats. An immunohistochemic…

2009

Settore BIO/17 - IstologiaCB1 Rimonabant Apoptosis Zucker rats
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Muscle Histopathological Abnormalities in a Patient With a CCT5 Mutation Predicted to Affect the Apical Domain of the Chaperonin Subunit.

2022

Recognition of diseases associated with mutations of the chaperone system genes, e.g., chaperonopathies, is on the rise. Hereditary and clinical aspects are established, but the impact of the mutation on the chaperone molecule and the mechanisms underpinning the tissue abnormalities are not. Here, histological features of skeletal muscle from a patient with a severe, early onset, distal motor neuropathy, carrying a mutation on the CCT5 subunit (MUT) were examined in comparison with normal muscle (CTR). The MUT muscle was considerably modified; atrophy of fibers and disruption of the tissue architecture were prominent, with many fibers in apoptosis. CCT5 was diversely present in the sarcolem…

Settore BIO/17 - IstologiaCCT5 neurochaperonopathies chaperonin neurodegenerative diseases neuropathies chaperone system muscle histopathology CCT5 apical domainSettore MED/38 - Pediatria Generale E SpecialisticaSettore BIO/16 - Anatomia UmanaSettore MED/30 - Malattie Apparato VisivoBiochemistry Genetics and Molecular Biology (miscellaneous)Molecular BiologyBiochemistrySettore CHIM/02 - Chimica FisicaFrontiers in molecular biosciences
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COX- Expression in the inflamed gingival tissue:Immunohistochemistry,Cytochemistry and Biochemistry test.

2007

Prostaglandins (PG) are chemical mediators for most physiological and pathological responses ,including cytoprotection of the gastric mucosa, blood coagulation,inflammation and pain (1,2,3). E2 Prostaglandins (PG2) play an important role of pathogenesis of periodontal diseases, since PG2 determines vasodilatation and increased vascular permeability, oedema and erythema.Therefore,it is not surprising to find high levels of PG2 in inflamed gingival tissues.Indeed ,in inflamed gingival tissue,PG2 levels of the Gingival Fluid (GCF) are known to be higher in periodontitis than in healthy gingiva.Moreover ,in different parodontitis the high PG2 level of the GCF is related to periodontal ligament …

Settore BIO/17 - IstologiaCOX-2epulisimmunohistochemistryinflamed gingival tissues biochemistry
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Extracellular vesicles in cancer pros and cons: The importance of the evidence-based medicine

2021

In this paper we want to introduce a hot topic for clinical and translational research in oncology and all the related medical fields: the "exosomology", i.e., the science that looks at exosomes as nanovesicular tools for theranostics. Exosomes are extracellular vesicles (EVs) of nanometric sizes actively secreted by normal and, above all, tumor cells. Among the EVs, exosomes are surely the most investigated and with the most promising results, mainly for what concerns their potential as representing the future of the so-called "liquid biopsy". Unfortunately, the huge and increasing amount of data coming from preclinical studies was not followed by an adequate number of clinical investigati…

Settore BIO/17 - IstologiaCancer ResearchExtracellular VesiclesEvidence-Based MedicineNeoplasmsBiomarkers TumorAnimalsHumansExosomesCancer Exosomes Extracellular vesiclesLiquid biopsyMicrovesiclesNanovesiscles
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