Search results for "kaksostutkimus"
showing 10 items of 45 documents
Early maturation and substance use across adolescence and young adulthood: A longitudinal study of Finnish twins.
2017
AbstractEarly maturation, indexed by pubertal development (PD), has been associated with earlier initiation and greater frequency of adolescent substance use, but this relationship may be biased by confounding factors and effects that change across development. Using a population-based Finnish twin sample (N = 3,632 individuals), we conducted twin modeling and multilevel structural equation modeling of the relationship between PD and substance use at ages 12–22. Shared environmental factors contributed to early PD and heavier substance use for females. Biological father absence was associated with early PD for boys but not girls, and did not account for the relationship between PD and subst…
Long-term leisure-time physical activity vs. inactivity, physical fitness, body composition and metabolic health characteristics : a co-twin control …
2013
Twin studies on the association of physical activity with cognitive and cerebral outcomes
2020
Regular physical activity (PA) offers positive effects on the human body. However, the effects of PA on cognition and in the brain are less clear. In this paper, we narratively review the relationship of PA with cognition and dementia, first from general perspective and then through genetically informed studies on the topic. Then we move on to imaging studies on exercise and brain anatomy first by presenting an overall picture of the topic and then discussing brain imaging studies addressing PA and brain structure in twins in more detailed way. Regarding PA and cognition or dementia, genetically informed studies are uncommon, even though the relationship between PA and cognitive ageing has …
Lifespan and skeletal muscle properties the effects of genetic background, physical activity and aging
2016
Obesity and metabolic disorders have become a notable world-wide epidemic. The pathogenesis of metabolic diseases, such as metabolic syndrome and type 2 diabetes, has begun to negatively affect life expectancy of current generations. Low aerobic capacity has shown to be a strong predictor of mortality both in rodents and humans. Exercise is known to increase an individual’s aerobic capacity; interestingly, recent studies have suggested that genetic background may play a significant role in the physical activity level of an individual. The purpose of this study was to investigate the role of genetic background and physical activity on skeletal muscle properties, metabolism and lifespan. The …
Genetic and environmental effects on resting electrocardiography and the association between electrocardiography and physical activity, walking endur…
2010
Towards powerful old age : association between hormone replacement therapy and skeletal muscle
2010
The role of heredity, other constitutional structural and behavioral factors in back function tests
2006
The objectives were 1) to determine the reliability of the measures of back function related factors, 2) to investigate the possibilities to detect changes in paraspinal muscles, and 3) to study the relative effects of heredity, constitutional and behavioral factors on three back function tests. Paraspinal muscle cross-sectional areas were obtained by magnetic resonance imaging from a sample of 210 men; anthropometric measures, isokinetic and psychophysical lifting capacity, and isometric back extension endurance tests were performed and current and past physical activity during leisure-time and at work were ascertained from a structured interview from a total sample of 600 men who were 35 …
Physical activity and health: Findings from Finnish monozygotic twin pairs discordant for physical activity.
2022
Genetic and early environmental differences including early health habits associate with future health. To provide insight on the causal nature of these associations, monozygotic (MZ) twin pairs discordant for health habits provide an interesting natural experiment. Twin pairs discordant for leisure-time physical activity (LTPA) in early adult life are thus a powerful study design to investigate the associations between long-term LTPA and indicators of health and wellbeing. We have identified 17 LTPA discordant twin pairs from two Finnish twin cohorts and summarize key findings of these studies in this paper. The carefully characterized rare long-term LTPA discordant MZ twin pairs have part…
Fyysisen aktiivisuuden ja aivojen tilavuuden yhteydet monozygoottisiilla kaksosilla
2016
Toivanen, Laura (2016) Fyysisen aktiivisuuden ja aivojen tilavuuden yhteydet monozygoottisilla kaksosilla. Terveystieteiden laitos, Jyväskylän yliopisto, pro gradu–tutkielma, 38s. Korkea fyysisen aktiivisuuden määrä on yhdistetty parempaan terveyteen, kuin myös aivojen harmaan ja valkean aineen, sekä aivo-selkäydinnesteen määrään, joiden volyymi on puolestaan yhteydessä hermostorappeumasairauksien syntyyn. Tutkimuksen tarkoituksena oli selvittää kuinka fyysisen aktiivisuuden taso vaikuttaa aivovolyymeihin, kehonkoostumukseen ja fyysiseen kuntoon nuorilla monozygoottisilla (MZ) mieskaksosilla, jotka ovat diskortantteja liikunnan suhteen. Tutkimusaineistoon poimittiin systemaattisesti väestöp…