Search results for "keratosis"

Possible strategy to prevent recurrence of actinic keratosis after treatment field-direct.

2020

Trichostasis spinulosa misdiagnosed as alopecia areata.

2020

Systematic search for neutropenia should be part of the first screening in patients with poikiloderma.

2011

Poikiloderma occurs in a number of hereditary syndromes, the best known of which is Rothmund-Thomson syndrome (RTS). Differential diagnoses include Dyskeratosis Congenita (DC) with high genetic heterogeneity and Clericuzio-type Poikiloderma with Neutropenia (CPN) due to mutations in the C16orf57 gene. Mutations in the RECQL4 gene are only observed in two thirds of RTS patients. In this study, 10 patients referred for syndromic poikiloderma and negative for RECQL4 sequencing analysis were investigated for C16orf57 mutations. Two C16orf57 heterozygous nonsense mutations (p.W81X and p.Y89X) were identified in a 5-year-old female child presenting with generalized poikiloderma, dental dysplasia,…

Porokeratosis of Mibelli: A New Indication for Photodynamic Therapy?

2013

Oral leukoplakia: the ongoing discussion on definition and terminology

2015

In the past decades several definitions of oral leukoplakia have been proposed, the last one, being authorized by the World Health Organization (WHO), dating from 2005. In the present treatise an adjustment of that definition and the 1978 WHO definition is suggested, being : “A predominantly white patch or plaque that cannot be characterized clinically or pathologically as any other disorder; oral leukoplakia carries an increased risk of cancer development either in or close to the area of the leukoplakia or elsewhere in the oral cavity or the head-and-neck region”. Furthermore, the use of strict diagnostic criteria is recommended for predominantly white lesions for which a causative factor…

Various forms of tobacco usage and its associated oral mucosal lesions

2016

Background To study the various forms of tobacco usage and its associated oral mucosal lesions among the patients attending Vishnu Dental College Bhimavaram. Material and methods An observational cross-sectional study was conducted in a total of 450 patients who were divided into three groups based upon type of tobacco use, as Group-1 Reverse smoking, Group-2 Conventional smoking, Group-3 Smokeless tobacco group and each group consists of 150 subjects. Results Reverse smoking was observed to be more prevalent among old females with smoker's palate and carcinomatous lesions being the most common. Conventional smoking was observed more in male patients with maximum occurrence of leukoplakia a…

Residents’corner August 2014. sQUIZ your knowledge!: Persistent papules on the lateral aspects of both palms

2014

A 52 year-old woman, with no relevant past medical history, presented with asymptomatic cutaneous lesions (that had first been noticed fifteen years before). On examination, several 2-3 mm reddish-yellow, well-defined and firm papules were noted on the lateral aspects of both hands (figure 1).What is your diagnosis (figure 1)? The answer is on the next page.The answer to sQuiz: AcrokeratoelastoidosisA biopsy of one of the lesions showed orthokeratotic hyperkeratosis with a central area bearing a [...]

Detection of laryngeal squamous cell carcinoma in a context of acrokeratosis paraneoplastica: Case report

2018

Background: Acrokeratosis paraneoplastica is an infrequent paraneoplastic disease in which cutaneous lesions appear and develop in a context of an underlying malignancy. Upper aerodigestive tract carcinomas are the most common neoplasias associated with this syndrome. The aim of this report is to raise awareness of this syndrome, since the recognition of the skin lesions could allow suspicion and diagnosis of the underlying neck malignancy at an early curable stage. Methods: We report a case of a 62-year-old life-long smoking male who presented a several months evolution of multiple skin lesions, affecting both ear lobes, hands and feet. He was referred for appropriate diagnosis and treatme…

Can the lesions induced with actinic keratosis become an enigma for dermatologists? Results of an open perspective study

2017

Different face skin diseases (basal cell carcinoma, actinic keratosis, rosacea, solar elastosis, etc.) could clinically manifest itself as erythematic patches, pimples or plagues. It is very hard to make the clinical exclusion in some cases of these diseases since their characters can partially overlap or certain lesion can mimic another one especially in the cases of skin areas affected with sun. Therefore, the histopathological analysis remains the “golden standard” of the dermatological diagnosis at skin diseases. Our study has shown that certified dermatologists detect actinic keratosis (AK) of face/head skin of I/II levels very well. Verdicts of dermatologists and pathomorfologists are…

Dyskeratosis congenita: Report of a case with literature review

2007

Leukoplakic lesion is not uncommon in clinical practice but its occurrence as a component of a syndrome is rare. Dyskeratosis congenita is a rare genodermatosis, which is characterized by triad of skin pigmentation, nail dystrophy and leukoplakic lesion in the oral cavity. It is important for dentists to now about Dyskeratosis Congenita because these leukoplakic lesions can spontaneously undergo malignant transformation. Majority of cases have been reported in dermatology or pediatrics literature whereas only few reports have appeared in dental literature. The purpose of reporting this case with review of recent literature is to create better awareness among dentists about the multisystem m…